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23 articles for “M.R. Madhav”
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Research ArticleOpen accessIn the author namesBridging Innovation and Access: Randomized, Single-Dose, Open-Label, Parallel-Group Bioequivalence Study of Generic and Innovator Injection Semaglutide in IndiaMayur Madhav Mayabhate, Nitin Kapure, Akhilesh Sharma, Radhakrishna VaddemSemaglutide, a long-acting Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is effective in improving glycemic control, reducing body weight, and lowering cardiovascular risk in Type 2 Diabetes Mellitus (T2DM). Limited accessibility of the innovator formulation underscores the need for bioequivalent generic alternatives. To assess the pharmacokinetic bioequivalence of a synthetic Semaglutide Injection (2 mg/1.5 mL) developed by Alkem Laboratories Ltd., India, compared … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 20 Apr 2026 · 2,637 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Dynamic Lifelong Learning Network for Real-Time Stock Prediction With Reinforcement TuningTalent Mawere, Selvaraj Rajalakshmi, Venu Madhav Kuthadi, Otlhapile DinakanyaneCompanies and investors require accurate market forecasting to make more informed decisions. Traditional methods for predicting stock market performance have become less useful considering the dynamic and volatile nature that characterizes stock markets today. In this paper, we propose an innovative Dynamic Lifelong Learning Network for stock market prediction. The model incorporates a hybrid convolutional long short-term memory with an … …Journal of Computer Science, Vol. 22, Issue 2 · 20 Feb 2026 · 1,829 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Collaborative Prediction of Presence of Arrhythmia in Human Heart with Electrocardiogram Data using Machine Learning Algorithms with AnalyticsSelvaraj Rajalakshmi, Kuthadi Venu MadhavHuman heart is the major organ of human being which could fail the other systems in the body at the same time. Hence predicting heart disease is one of the challenging researches that requires meticulous analysis of heart rhythms properly. The irregular heart rhythms or beat is referred to as the Arrhythmia where heart rhythms with low or high rates … …Journal of Computer Science, Vol. 15, Issue 2 · 22 Feb 2019 · 7,513 accessesView PDFCite
Research ArticleOpen accessIn the author namesEngineering of Ground for Liquefaction Mitigation Using Granular Columnar Inclusions: Recent DevelopmentsA. Murali Krishna, M.R. MadhavProblem statement: Liquefaction was the most hazardous damage during an earthquake. Ground improvement techniques were employed to mitigate liquefaction hazards. Most common methods to improve engineering properties of soils are densification, reinforcement, grouting/mixing and drainage. Among various remedial measures available, installation of columnar granular inclusions is the most widely adopted method for liquefaction mitigation. Approach: Columnar granular inclusions function as … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 3 · 30 Sep 2009 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the author namesUncertainty-Aware Ensemble Models for Improved Defect Detection in Noisy DataMadhavi Perla, Gadi Lava Raju, A Radha Krishna et al.Software defect prediction plays a crucial role in ensuring software quality and reliability, especially as modern systems become more complex and data rich. This study introduces an uncertainty-aware ensemble learning framework aimed at improving defect classification performance in noisy and imbalanced datasets, particularly those from the PROMISE and NASA KC1 repositories. The proposed model integrates multiple classifiers in a multi-learner … …Journal of Computer Science, Vol. 22, Issue 4 · 27 Apr 2026 · 1,549 accessesView PDFCite
Research ArticleOpen accessIn the author namesAn Efficient Video Compression Framework using Deep Convolutional Neural Networks (DCNN)Kommerla Siva Kumar, P. Bindhu Madhavi, K. JanakiIn the current world, video streaming has grown in popularity and now accounts for a large percentage of internet traffic, making it challenging for service providers to broadcast videos at high rates while utilizing less storage space. To follow inefficient analytical coding design, previous video compression prototypes require non-learning-based designs. As a result, we propose a DCNN technique that integrates … …Journal of Computer Science, Vol. 18, Issue 7 · 13 Jul 2022 · 6,157 accessesView PDFCite
EditorialOpen accessIn the author namesCURRENT SCENARIO OF THERAPEUTICS FOR EBOLA VIRUS DISEASEML Arvinda Swamy, Madhavan P.N. Nair, Shailendra K. SaxenaCurrently various countries in Africa, including Liberia, Sierra Leone, Guinea, Nigeria, are facing disaster due to Ebola Virus Disease (EVD), which is primarily caused by Ebola virus. 2014 outbreak of Ebola associated viral haemorrhagic fever has 55-60% fatality rate. The incubation period of Ebola is below 21 days; once the appearance of symptoms starts the person will be infective. As … …American Journal of Infectious Diseases, Vol. 10, Issue 3 · 3 Sep 2014 · 7,746 accessesView PDFCite
Research ArticleOpen accessIn the author namesFlooding Attack Aware Secure AODVS. Madhavi, K. DuraiswamyProviding security in a Mobile Ad hoc Network (MANET) is a challenging task due to its inherent nature. Flooding is a type of Denial of Service (DoS) attack in MANET. Intentional flooding may lead to disturbances in the networking operation. This kind of attack consumes battery power, storage space and bandwidth. Flooding the excessive number of packets may degrade the … …Journal of Computer Science, Vol. 9, Issue 1 · 27 Feb 2013 · 7,536 accessesView PDFCite
Research ArticleOpen accessIn the author namesRendezvous with Tat: Transactivator of Transcription during Human Immunodeficiency Virus PathogenesisSneham Tiwari, Madhavan P.N. Nair, Shailendra K. SaxenaAcquired immune deficiency syndrome is a deadly disease caused by HIV, declared as a global catastrophe engulfing millions of lives per year. It took ~1.8 million lives in the year 2010 alone, as per reports of UNAIDS. HIV-1 is an enveloped retrovirus, having genome composed of two copies of ssRNA. It attacks the T-lymphocytes of the hosts, causes several multifaceted … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 7,627 accessesView PDFCite
Research ArticleOpen accessIn the author namesEvaluation of Nested PCRs targeting the BI and SAG2 Genes For Detection of Toxoplasma gondii Genome in Aqueous Humor From HIV Positive Toxoplasma Retinochoroiditis Patients in a Tertiary Eye HospitalB. Mahalakshmi, K.L. Therese, R. Kirthika et al.Abstract: Problem statement: To evaluate nPCR targeting B1 gene (primer set 1) with 3 other nPCRs targeting B1 gene (primer set 2), 3' end of SAG2 and 5' end of SAG2 gene, for detection of Toxoplasma gondii (T. gondii) genome on AH from HIV positive TRC patients. Approach: DNA extracted from AH of 12 TRC patients and 12 controls (patients … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Dec 2010 · 6,887 accessesView PDFCite