Research ArticleOpen accessIn the author namesA Sled Dog Model for Positive Health Effects of Weight Management and ExerciseLaura Falkenstein, Scott Jerome et al.Obesity is a significant risk factor for metabolic syndrome and type II diabetes. Physical activity and/or dietary modification can reduce the incidence of obesity. Marginal fitness levels limit the efficacy of exercise training, and most humans choose from a wide range of dietary strategies to lose weight. Despite these limitations, exercise in the absence of weight loss may offer protective … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 23 Feb 2023 · 6,151 accessesView PDFCite
Research ArticleOpen accessIn the author namesWeight Gain, Conditioning and Metabolic Syndrome: A Sled Dog ModelAline Collin, Shannon Jimmie, Arleigh Reynolds et al.Type II Diabetes (T2D) and insulin resistance are growing national health concerns. Obesity is a risk factor for developing T2D and is associated with chronic and systemic inflammation. Exercise on the other hand has been shown to improve glucose metabolism and insulin sensitivity. We investigated the effects of conditioning and weight gain on adiponectin, tumor necrosis factor and glycosylated hemoglobin, … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 18 Aug 2019 · 7,728 accessesView PDFCite
Research ArticleOpen accessIn the author namesEFFECT OF ZINC OXIDE NANOPARTICLES ON NEUROBLASTOMA SH-SY5Y CELLSJinghui Zheng, Theresia Schnurr, Kriya Dunlap et al.The Arctic and sub-arctic regions are impacted by the growth of the global nanotechnology industry and the transport of chemicals to the North. New nanotechnology industries, such as neural prothesis, are bringing nanomaterials in direct contact with neurons and glial cells. Nanomaterials have unique chemical and physical properties that may lead to toxicological effects by interfering with normal cellular metabolism. … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 2 · 4 Jul 2014 · 8,488 accessesView PDFCite
Research ArticleOpen accessIn the author namesMercury in Hair of Muskox on the Seward PeninsulaClaudia Ihl, R. Terry Bowyer, Kriya L. Dunlap, Lawrence K. DuffyProblem statement: Muskoxen (Ovibus moschatus) are distant relatives of sheep (Caprinae) and have roamed the Arctic for a million years, with populations reaching North America between 150,000 and 250,000 years ago. Muskox populations could be negatively influenced by climate change and increased exposure to contaminants. Since the snow depth is a critical factor in their ecology, effects could occur throughout … …American Journal of Environmental Sciences, Vol. 8, Issue 2 · 24 Mar 2012 · 7,005 accessesView PDFCite
Research ArticleOpen accessIn the author namesCross-Latitudinal, Seasonal and Diurnal Comparisons in Thyroid Hormone Concentrations in Sled DogsKriya L. Dunlap, Arleigh J. Reynolds, Kent R. Refsal et al.Problem Statement: Hypothyroidism has been a common disorder in humans and dogs. Amongst a sundry of functions, the thyroid gland plays a key role in metabolism and consequently, hypothyroidism has been a common diagnosis for a decrease in performance in sled dogs. Research has indicated that a variety of environmental factors influence thyroid hormone production, of which, light exposure, climate, … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 4 · 31 Dec 2008 · 7,184 accessesView PDFCite