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11 articles for “Influenza Viruses”

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Research ArticleOpen accessIn the keywordsSevere and Fatal Influenza Cases in Russia in 2014-2015Svetlana V. Svyatchenko, Alexander G. Durymanov, Ivan M. Susloparov et al.This paper aims to characterize herd immunity of the population inhabiting Asian part of Russia before influenza epidemic and to describe influenza viruses isolated from severe cases including cases with fatal outcomes in the 2014-2015 epidemic season. HI test enabled us to study 3888 serum samples from healthy individuals including 1939 samples collected from poultry farm workers. We showed that … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 24 Dec 2016 · 7,064 accessesView PDFCite
Short CommunicationsOpen accessIn the keywordsMolecular Testing for Respiratory Tract Infections May Have Favorable Impact on Real-world Healthcare CostsAzia Evans, Vijay Singh, Pallavi Upadhyay et al.Molecular testing by Polymerase Chain Reaction (PCR) has improved diagnostic performance to inform appropriate treatment. However, its impact on healthcare utilization and costs related to respiratory tract infections are yet to be studied in detail. The aim of this study is to evaluate the costs of healthcare utilization following traditional culture and molecular PCR diagnostic testing for respiratory tract infections. … …American Journal of Infectious Diseases, Vol. 20, Issue 3 · 15 Jan 2025 · 5,262 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAn Informetric Analysis of Studies on Influenza Vaccines and VaccinationVadim Nikolaevich Gureyev, Nikolay Alekseevich Mazov, Tatyana Nikolaevna Ilyicheva, Sergei Ivanovich BazhanInfluenza is one of highly contagious acute virus diseases that primarily affects respiratory ways. Annual seasonal epidemics afflict approximately 15% population worldwide and lead to 250,000–500,000 deaths each year. That is why studies on influenza vaccines and vaccination that prevent spreading of the virus remain highly important. This paper presents the results of informetric analysis of publications on influenza vaccine … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 13 Dec 2017 · 7,274 accessesView PDFCite
Research ArticleOpen accessIn the abstractInflammatory Effects of Co-Exposure to Heavy Metals (Cd and Pb) and Respiratory Viruses (229E, OC43, and H3N2) on IL-6 and IL-8 Responses in U87 Glioblastoma CellsHyeokjun Yun, Qian-Wen Wang, Jae Kyung KimCo-exposure to heavy metals and viruses can pose threats to cellular health by increasing cytotoxicity and inflammatory cytokine expression. We aimed to elucidate the interactions between these factors inhuman glioblastoma cells (U87). U87 cells were exposed to influenza A virus (H3N2), coronaviruses OC43 and 229E, and heavy metals Cd and Pb. Cell viability and cytotoxicity were assessed through WST-8 and … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 5 Jul 2025 · 5,505 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytokine Expression During the Early Response of A549 Cells to Infection with Influenza Virus, Alphacoronavirus and BetacoronavirusQian Wen Wang, Jae Kyung KimThe escalating incidence of coronavirus infections underscores the critical need for a comprehensive understanding of the differential impacts of Human Coronaviruses (HCoVs) belonging to the Alphacoronavirus and Betacoronavirus genera. This study investigated the varying effects of HCoV-229E (Alphacoronavirus), HCoV-OC43 (Betacoronavirus), and influenza A virus subtype H3N2 on A549 cell viability and cytokine expression. Results showed that H3N2 triggered a more … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 6 Jul 2024 · 4,554 accessesView PDFCite
Review ArticleOpen accessIn the abstractRecent Advances in Point of Care Diagnostic Tools: A ReviewLaura Wessels, Haider RaadGlobally, there is a great need for portable, inexpensive diagnostic tools that can provide quick, accurate results using relatively small sample volumes. Point-Of-Care (POC) measurements of human saliva, sweat and/or blood capable of detecting glucose levels, foreign pathogens such as bacteria, fungi and many different viruses (HIV, Ebola, Influenza, etc.) that use microfluidics and optofluidics are close to commercial availability. … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 28 Nov 2016 · 8,234 accessesView PDFCite
Research ArticleOpen accessIn the abstractDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,669 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluenza Surveillance in Russia Based on Epidemiological and Laboratory Data for the Period from 2005 to 2012Sominina Anna, Elena Burtseva, Mikhail Eropkin et al.Exchange of information on and sharing of influenza viruses through the GISRS network has great significance for understanding influenza virus evolution, recognition of a new pandemic virus emergence and for preparing annual WHO recommendations on influenza vaccine strain composition. Influenza surveillance in Russia is based on collaboration of two NICs with 59 Regional Bases. Most epidemiological and laboratory data are … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 14 Oct 2013 · 8,759 accessesView PDFCite
Research ArticleOpen accessIn the abstractLevamisole Enhances Cell-Mediated Immune Responses and Reduces Shedding of H9N2 Avian Influenza Virus in Japanese Quails (Coturnix coturnix japonica)Tahoora Shomali, Najmeh Mosleh, Arash AlaeddiniProblem statement: Regarding the role of Japanese quails (Coturnix coturnix japonica) in reassortment and spreading of avian influenza (AI) viruses and inadequate protection of vaccination in this species, the present study aimed to evaluate the effect of levamisole as an immunomodulatory agent on cell-mediated immunity (CMI), antibody responses and shedding of H9N2 AI virus in experimentally infected quails. Approach: On … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 6 Mar 2012 · 7,651 accessesView PDFCite
Research ArticleOpen accessIn the abstractSearching of Main Cause Leading to Severe Influenza A Virus Mutations and Consequently to Influenza Pandemics/EpidemicsGuang Wu, Shaomin YanThe unpredictable mutations in the proteins from influenza A virus lead to the great difficulty in prevention of possible outbreak of bird flu and pandemic/epidemic of influenza. This unpredictability is due to the fact that we know little about the causes that lead to the mutations. In three of our recent studies on the hemagglutinins from influenza A virus, we … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 9,970 accessesView PDFCite