Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

19 articles for “Hepatocytes”
Set a search alert
Research ArticleOpen accessEvery word in the titleEvidences of Apoptosis in Hepatitis C Virus-Infected Hepatocytes and Peripheral Blood Monocuclear Cells in the Absence of Liver InjuryViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Understanding the mechanism of Hepatitis C Virus (HCV) pathogenesis is an important part of HCV research. In this study, the presence of apoptosis in HCV-infected liver and Peripheral Blood Mononuclear Cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA was investigated. The samples obtained from 21 patients were studied by in situ Hybridization (ISH), Immunofluorescence, TUNEL … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,975 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvidences of Hepatitis C Virus Replication in Hepatocytes and Peripheral Blood Monocuclear Cells from Patients Negative for Viral RNA in SerumViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.In this study, we examined the expression of hepatitis C virus (HCV) components in hepatocytes and peripheral blood mononuclear cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA. The samples obtained from 25 randomly selected patients (13 of 25 patients showed no histological evidences of chronic hepatitis and had normal serum ALAT and GGTP levels) were … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 7,164 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Dynamic of Afamin and Alpha-Fetoprotein Expression during Rat Liver DevelopmentIndriyani, Isabella Kurnia Liem, Puspita Eka Wuyung et al.Liver has a high level of Alpha-fetoprotein which is assumed to be important for mammalian development. However, Alpha-fetoprotein knockout studies in mice suggested that despite the absence of Alpha-fetoprotein, mice developed normally; the only abnormality observed was infertility in female mice. There are indications that Afamin, a protein that has a gene sequence located on the same chromosome as Alpha-fetoprotein, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 5 Feb 2021 · 6,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractFerulic Acid in Chinese Herbal Medicine: Regulating Autophagy for Oxidative Damage ReductionZhiyuan Lv, Qiaozhen Zhao, Shanbin Chen et al.Ferulic Acid (FA) is the primary functional component in herbal plants and traditional fermented foods. To comprehend the mechanism of action of ferulic acid, in terms of its regulation of autophagy, antioxidants and the inhibition of inflammatory pathways, the study was conducted. Oxidatively damaged human-derived hepatocytes were treated with FA and the processing concentration of FA is from 50-800 μm. … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 1 Jun 2024 · 5,483 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Hepatocellular Toxicity of Enavatuzumab, a Humanized Anti-TweakR AntibodyDonghee Choi, Yanhong Zhu, Debra Tien Chao et al.In a Phase 1 clinical study, treatment with enavatuzumab, a humanized monoclonal antibody to TweakR, resulted in liver toxicity in a subset of patients. The objective of this current study was to evaluate the ability of preclinical studies to predict liver toxicity in humans. Enavatuzumab was evaluated in cynomolgus monkeys, where serum liver enzyme and cytokine levels were measured and … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 2 · 9 Nov 2017 · 7,719 accessesView PDFCite
Review ArticleOpen accessIn the abstractSpecific Markers for Hepatic Progenitor CellsMsy Rulan Adnindya, Indriyani, Ahmad Azmi Nasution, Isabella Kurnia LiemOne of mammalian organs that has remarkable ability to regenerate, liver, regenerates through the proliferation of hepatocytes or proliferation and differentiation of the stem cells resident. Some literatures states that these stem cells, the Hepatic Progenitor Cells (HPCs), are oval cells that have bipotential ability to be cholangiocytes and hepatocytes. However, the mechanisms of programming, activation of proliferation and maturation/differentiation … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 13 Jul 2017 · 9,286 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmeliorative Impacts of Tribulus terrestris Against Ivermectin-Induced Hepato-Renal Toxicity in Rabbit: Pharmacological and Histopathological StudySally I. Ismaiel, Sameh M. Farouk, Raafat A. El-Ramady, Waleed F. KhalilThe current work aimed to investigate the protective effects of Tribulus terrestris extracts against ivermectin-induced hepatic and renal toxicity in male rabbit. Selenium plus vitamin E was used as a comparative standard drug to evaluate the efficacy of Tribulus terrestris extract on some hematological parameters, kidney and liver enzymes as well as associated histopathological changes. This work was carried out … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 12 Jan 2017 · 7,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractTAURINE ATTENUATES HEPATIC AND CARDIAC DAMAGE AND APOPTOSIS IN RABBITS FED A HIGH-FAT DIETGamal Hasan Abdel-RahmanA hypercholesterolemia diet has been associated with the hepatic and cardiac abnormalities and the pathological changes. The present work was designed to investigate the histological and immunohistochemical changes in the liver and heart of rabbits when fed high fat diet and the possible protective role of an antioxidant "taurine". Twenty-four male white New Zealand rabbits were divided into four groups, … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 28 Dec 2013 · 6,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractGENERALIZED REGRESSION NEURAL NETWORK BASED EXPERT SYSTEM FOR HEPATITIS B DIAGNOSISC. Mahesh, E. Kannan, M. S. SaravananHepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus. The virus interferes with the function of the liver while replicating in hepatocytes. It is a major global health problem and the most serious type of viral hepatitis. Chronic liver disease is caused by viral hepatitis and putting people at high risk of death from cirrhosis … …Journal of Computer Science, Vol. 10, Issue 4 · 3 Dec 2013 · 6,983 accessesView PDFCite