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16 articles for “Hepatitis B Virus (HBV)”
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Research ArticleOpen accessIn the keywordsUltrastructural Evidences of Hepatitis B Infection in Human Liver Biopsies Disclose Complex Assembly and Morphogenesis Pathways for Hepatitis B VirusViviana Falcon, Ivon Menéndez, Nelson Acosta-Rivero et al.Despite of recent advances on acknowledge of hepatitis B virus (HBV) structure and biology, little is known about the morphogenesis and release of virions. In this study, the ultrastructural analysis of HBV components in liver biopsies from chronically HBV-infected patients disclosed complex assembly and morphogenesis pathways for HBV. HBV core (HBcAg) and surface (HBsAg) antigens were specifically identified in all … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,091 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGENERALIZED REGRESSION NEURAL NETWORK BASED EXPERT SYSTEM FOR HEPATITIS B DIAGNOSISC. Mahesh, E. Kannan, M. S. SaravananHepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus. The virus interferes with the function of the liver while replicating in hepatocytes. It is a major global health problem and the most serious type of viral hepatitis. Chronic liver disease is caused by viral hepatitis and putting people at high risk of death from cirrhosis … …Journal of Computer Science, Vol. 10, Issue 4 · 3 Dec 2013 · 6,983 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHepatitis B Diagnosis Using Logical Inference and Self-Organizing MapGhumbre Shashikant Uttreshwar, A.A. GhatolDespite all the standardization efforts made, medical diagnosis is still regarded as an art owing to the fact that that medical diagnosis requires an expertise in handling the uncertainty which is unavailable in today's computing machinery. Though artificial intelligence is not a new concept it has been widely recognized as a new technology in computer science. Numerous areas such as … …Journal of Computer Science, Vol. 4, Issue 12 · 31 Dec 2008 · 6,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnostic Potential of Inflammatory Biomarker Levels in the Serum of Patients with Hepatitis B Infection: A Retrospective StudyHyeokjun Yun, Bo Kyeung Jung, In Soo Rheem et al.This study aimed to evaluate the diagnostic biomarker potential of C-Reactive Protein (CRP) and Procalcitonin (PCT) levels in the serum of individuals infected with the Hepatitis B Virus (HBV). The patients were divided into two age groups: Younger (<60 years) and older (≥60 years). An Electrochemiluminescence Immunoassay (ECLIA) platform was employed for the serological analysis to quantify the biomarker levels. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 10 Aug 2023 · 5,270 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Thyroid Hormone Level Alterations in Hepatitis B-Positive Serum Using a Quantitative Immunofluorescence Assay: A Randomized Controlled TrialHyeokjun Yun, Bo Kyeung Jung et al.This retrospective study aimed to assess the differences in serum biomarker levels, specifically thyroid hormone (free T4 and Thyroid-Stimulating Hormone [TSH]) levels, according to the presence or absence of Hepatitis B Virus (HBV) infection. Using a quantitative immunofluorescence assay, we analyzed serum samples from patients with confirmed HBV infection at Dankook University Hospital in Cheonan Province, Republic of Korea, between … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 31 Jul 2023 · 5,030 accessesView PDFCite
Research ArticleOpen accessIn the abstractMeasurement of the Gene Expression and Polymorphisms of c-myc and p53 Genes in HBV Infected PatientsFayed Koutb, Salah Abdel-Rahman, Ehab Hassouna, Amany HaggagThis study explained the c-myc and p53 gene expression and polymorphisms in chronic (40), cirrhosis (30) and Hepatocellular Carcinoma, (HCC) (30) patients related to Hepatitis B Virus (HBV) infection and healthy control (50) in Egypt. Where, c-myc (intron 8) and p53 (codon 72) gene expression and polymorphisms were determined using qRT-PCR and PCR-RFLP techniques. The results showed that c-myc gene … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 22 Feb 2021 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Association of HLA Class II Alleles with the Response to Alfa-Interferon/Ribavirin Therapy in Chronic Hepatitis C PatientsAwny Aly Abol-Ez Gawish, Nahla Abd El-Hamid Mohammed, Rasha Adel Sayed Ahmed Hussein, Elsaid Galal El-BadrawyHuman Leucocyte Antigens (HLA) class II appears to play an important role in the individual’s immune response to viral infection. The present study was aimed at assessment of the relationship between HLA DRB1 alleles and the response to HCV combined therapy in Chronic Hepatitis C patients (CHC). We enrolled a total of 44 chronically infected HCV patients without Hepatitis B … …American Journal of Immunology, Vol. 11, Issue 3 · 12 Nov 2015 · 6,700 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relation between Helicobacter Pylori Infection and Hepatocellular Carcinoma in Egyptian PatientsWaleed Mohamed SeragThis work to show the relation between Helicobacter Pylori infection and Hepatocellular Carcinoma in Egyptian patients. This study was completed at National liver institute in Egypt. Patients in this study were recognized cases of chronic Hepatitis C virus liver disease with and without hepatocellular carcinoma. Serum samples of patients of hepatocellular carcinoma with hepatitis C Virus (HCV) of 40 male … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 25 Jun 2015 · 7,016 accessesView PDFCite
EditorialOpen accessIn the abstractCRISPR-CAS SYSTEM: A FEASIBLE SOLUTION FOR GETTING RID OF PERSISTENT VIRAL INFECTION?Zhaohua ZhongMany viruses, including DNA and RNA viruses, can persistently replicate in the infected cells and cause a prolonged damage. Herpes viruses can be latent in its host cells. Human Immunodeficiency Virus (HIV) reversely transcripts its RNA genome to DNA and integrates to the host’s chromosome. Hepatitis B Virus (HBV) and Human Papilloma Virus (HPV) persistently stay in the host cells … …Current Research in Virology, Vol. 3, Issue 1 · 10 Nov 2014 · 12,614 accessesView PDFCite