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16 articles for “HLA-G”
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Research ArticleOpen accessEvery word in the titleThe Association of HLA Class II Alleles with the Response to Alfa-Interferon/Ribavirin Therapy in Chronic Hepatitis C PatientsAwny Aly Abol-Ez Gawish, Nahla Abd El-Hamid Mohammed, Rasha Adel Sayed Ahmed Hussein, Elsaid Galal El-BadrawyHuman Leucocyte Antigens (HLA) class II appears to play an important role in the individual’s immune response to viral infection. The present study was aimed at assessment of the relationship between HLA DRB1 alleles and the response to HCV combined therapy in Chronic Hepatitis C patients (CHC). We enrolled a total of 44 chronically infected HCV patients without Hepatitis B … …American Journal of Immunology, Vol. 11, Issue 3 · 12 Nov 2015 · 6,700 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleReal Time Object Tracking and Protection: Hybrid Logistics Architecture in Ubiquitous Environments (HLAiUE)Abdul Jawwad Patel, Abeer Alsadoon, P.W.C. Prasad, A. ElchouemiRealtime object security and vehicle tracking have not been successfully implemented in commercial vehicles due to limitations in processing large amount of data and hardware capabilities. This paper aimed to improve the object security, processing power and data storage in a distributed environment. The proposed system (HLAiUE) consists of a three-layer architecture, first layer is used to collect data, second … …American Journal of Applied Sciences, Vol. 15, Issue 8 · 17 Oct 2018 · 7,520 accessesView PDFCite
Research ArticleOpen accessIn the keywordsFactors Affecting the Response to Interferon Alpha Therapy in Egyptian HCV PatientsNaglaa F. Alhusseini, Fathy M. Serry, Ashraf A. Kadry, Heba KhairyHepatitis C Virus (HCV) infection is one of the main causes of chronic liver disease worldwide. Egypt has the highest prevalence of Hepatitis C Virus (HCV) in the world, estimated nationally at 14.7%. knowledge of the predictors of Sustained Viral Response (SVR) to Pegylated Interferon (PEG-INF) and Ribavirin (RBV) therapy in patients with chronic hepatitis C is crucial for selecting … …American Journal of Immunology, Vol. 11, Issue 3 · 30 Sep 2015 · 6,619 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHow Micrornas Affect the Expression of Human Leukocyte Antigeng in PregnancyAyla Carmel Kempers, Marie Van Dijk, Cees OudejansThe expression of Human Leukocyte Antigen G (HLA-G) on Fetal Extravillous Trophoblast (EVT) cells during pregnancy plays an important role in preventing the fetus from rejection by suppressing the maternal immune system. Decreased expression levels of HLA-G have already shown to be associated with several complications of pregnancy such as pre-eclampsia. However, it remains largely unknown how HLA-G gene expression … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,124 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBayesian Determination of Disease Associated Differences in Haplotype BlocksIvan Kozyryev, Jing ZhangProblem statement: While experimental ascertainment of haplotype blocks in the genome-scale case-control studies is expensive, accurate computational phasing is still a daunting task for bioinformatics approaches. We used a statistical method to determine differences, potentially associated with a certain disease, in linkage disequilibrium block boundaries in whole-genome Single Nucleotide Polymorphisms (SNPs) data. Approach: We utilized a Bayesian model for calculating … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 14 Feb 2012 · 8,423 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,962 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease InhibitorsOtto O. YangHIV-1-protease inhibitors have received growing attention as agents that can affect proteases in human proteasomes, with potentially deleterious effects for HIV-1-specific cellular immunity. Studying the antiviral activity of HIV-1-specific CTL that recognize an epitope that is presented at limiting concentrations on infected cells, we find that several HIV-1 protease inhibitors do not affect their function. These data indicate that these … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessIn the author namesPrevalence of HSV1 and HSV2 among HIV Patients in Northern South Africa as Determined by Real Time PCR in Urine SamplesAmidou Samie, Hlayisani Preclude Mnisi, Mary Noluthando RamantswanaThe present study determined the prevalence of HSV-1 and 2 among HIV patients in Northern South Africa and identified potential risk factors. Urine samples were collected from patients attending different HIV clinics in Limpopo Province. Total genomic DNA was isolated from these samples using GenElute Blood Genomic DNA Kit and real time PCR protocols were used for the detection of … …American Journal of Infectious Diseases, Vol. 13, Issue 1 · 18 Jul 2017 · 7,911 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Best Candidates Method for Solving Optimization ProblemsHlayel Abdallah AhmadProblem statement: This study is about describing solution technique called Best Candidates Method (BCM) for solving optimization problems; the goal is to minimize the computation time to get the optimal solution. In this study I apply the BCM to the linear assignment problems (LAP) that is one of the optimization problems in the Operation Research (OR). Approach: The optimization problem … …Journal of Computer Science, Vol. 8, Issue 5 · 27 Feb 2012 · 8,341 accessesView PDFCite
Literature ReviewOpen accessIn the abstractStaphylococcus aureus Vaccine Candidate from MRSA Isolates: The Prospect of a Multivalent VaccineNovra Arya Sandi, Tenri Ashari Wanahari, Isabel MacPhillamy et al.Staphylococcus aureus (S. aureus) is a major cause various infections in humans and animals throughout the world. The increasing incidence of S. aureus infection, particularly methicillin-resistant Staphylococcus aureus (MRSA) is complicated by the antibiotic-resistance phenomenon. Thus, it requires new strategies to prevent wider scale of its incidence occurring. Preventative methods against infectious diseases through vaccination can prevent, control and reduce … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 27 Aug 2015 · 8,471 accessesView PDFCite