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35 articles for “Genomic Analysis”
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Research ArticleOpen accessPhrase in the titleIsolation, Identification and Genomic Analysis of Plesiomonas shigelloides Isolated from Diseased Percocypris pingi (Tchang, 1930)Lei Pan, Shuiyi Liu, Xuwei Cheng et al.Recently, the outbreak of a serious infectious disease of unknown etiology was noted in Percocypris pingi (Tchang, 1930) farms in Yunnan province. Due to currently limited information, we aimed to identify the pathogen isolates, determine the susceptibility of the isolates, evaluate the pathogenicity and analyze the genome of the representative strain. Ten strains of Gram-negative rods were isolated from diseased … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 22 Dec 2017 · 8,836 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExplainability Aware Heterogeneous Temporal Graph Transformer for Automated Genetic Disorder Detection from Genomic DataPuvaneswari Subramaniapillai, Indirani Govindasamy, Revathy GurumurthyGenetic disorders affect millions worldwide, posing major challenges for accurate diagnosis and effective treatments. New developments in genomic technologies, especially Next-Generation Sequencing (NGS), have enhanced the classification of genetic modification and improved diagnostic abilities. Moreover, the Machine Learning (ML) and Deep Learning (DL) methods emerged as efficient tools for evaluating the intricate genomic data and determining the patterns, which can … …Journal of Computer Science, Vol. 22, Issue 11 · 14 Oct 2026 · 566 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUMPM-Net: A Multimodal Deep Learning Framework for Colorectal Cancer PrognosisK. Muthuchamy, S K. Piramu PreethikaColorectal cancer (CRC) is one of the most common cancers worldwide, for which early prediction of patient outcomes is important for personalised treatment planning and to improve survival. However, current prediction systems are limited in the fact that they are based on single-modality data and cannot capture the complex interactions between clinical, imaging, and genomic factors. To overcome these shortcomings, … …Journal of Computer Science, Vol. 22, Issue 9 · 20 Sep 2026 · 613 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAnalysis of the Cytogenetic Status, Genome Instability, and Adaptive Potential of the Kazakh Tobet DogOksana Cherednichenko, Anastassiya Pilyugina, Dinara Azizbekova et al.In recent years, interest in indigenous dog breeds has increased. The Tobet is a unique breed of Kazakh livestock guardian dogs adapted to nomadic pastoralism that developed over thousands of years across Central Asia and Turkestan. Currently, the Tobet breed faces critical endangerment. Its conservation and sustainable breeding require thorough analysis of hereditary characteristics, genome stability, and adaptive potential. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 19 Feb 2026 · 1,891 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLeaf Surface Bacterial Colonization in Response to Brevicoryne brassicae (L.) Infestation of Brassica chinensis L.Shaon Raychaudhuri, Inga Mewis, Christian UlrichsProblem statement: Epiphytic population is an intrinsic part of the leaf surface. The effect of stress like insect infestation is not well understood. The aim of the study was to determine possible effects of insect infestation on bacteria community. Approach: The leaf surface microbial profile of Brassica rapa ssp. chinensis (L.) was investigated using a culture-dependent approach under normal and … …Current Research in Microbiology, Vol. 1, Issue 2 · 31 May 2011 · 7,859 accessesView PDFCite
Review ArticleOpen accessIn the abstractGenomic Regions and Candidate Genes Associated With Semen Traits in Rams: A Systematic GWAS Review With Implications for South African Sheep BreedsNhlakanipho Sam Zulu, Khoboso Christine LehloenyaRam fertility is a key determinant of reproductive efficiency in sheep production systems, particularly under extensive and semi-extensive conditions prevalent in South Africa. Semen quality traits, including ejaculate volume, sperm concentration, motility, and cryotolerance, exhibit measurable genetic variation and are increasingly investigated using genomic approaches. This systematic review synthesizes evidence from three eligible Genome-Wide Association Studies (GWAS) analyses that have … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 3 · 26 Oct 2026 · 50 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,982 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Genomics of Xylella fastidiosa Subsp. Pauca and Insights on its Current and Potential Movements in EcuadorCarlos Bolanos-Carriel, Eliana Granja Guerra, Jaris Veneros et al.Xylella fastidiosa subsp. Pauca causes Coffee Leaf Scorch (CLS). It is a major threat to coffee production in most South and Central American countries. X. fastidiosa is prone to intersubspecific recombination, and it is believed that this species became pathogenic in citrus and coffee due to recent mutation events and gene flow between closely related strains. CLS epidemics have not … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 23 Nov 2024 · 6,172 accessesView PDFCite