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13 articles for “Gene Prediction”
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Research ArticleOpen accessEvery word in the titleIn Silico Sequence Analysis, Structure Prediction and Function Annotation of Melanocortin 1 Receptor Gene (MC1R) from the Guppy Poecilia reticulataAbdul Khader Sultan Mohideen, Mehboob Asrar Sheriff, Kareem AltaffThe common guppy, Poecilia reticulata is one of the most popular aquarium fish used as a model organism in toxicology, embryology and genetical studies. Vibrant colors in males are a secondary sexual character which attracts the females for mating. Pigmentation in guppy is found to be linked with melanin synthesis. Melanocortin genes are involved in the synthesis of melanin pigments. … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 17 Nov 2015 · 8,614 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn Silico Prediction and Functional Characterization of Genes Related to Abiotic and Biotic Stresses in Chickpea (Cicer arietinum)Sukhdeep Kaur, Satendra Singh, Gitanjali Tandon et al.Chickpea (Cicer arietinum L.) is second largest grown legumes worldwide contributing 75% of total pulse production. It is a cool season legume crop and grown in tropical and subtropical areas. Due to drastic climatic changes, chickpea suffers from many biotic (blight and wilt) and abiotic (salinity, drought, cold) stresses that directly impact the growth and yield. In our study, we … …Current Research in Bioinformatics, Vol. 7, Issue 1 · 25 Sep 2017 · 14,188 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractModel Classification for Predicting the Post-Translational Modification (PTM) Glycosylation in Sequence O Using an Extreme Gradient Boosting AlgorithmDamayanti, Sutyarso et al.Post Translational Modification (PTM) is an important mechanism involved in regulating protein function. Post-translational modification refers to the addition of covalent and enzymatic modifications of proteins in protein biosynthesis, which has an important role in modifying protein function and regulating gene expression. One of the post-translational modifications is glycosylation. Glycosylation is the addition of a sugar group to a protein … …Journal of Computer Science, Vol. 20, Issue 7 · 29 Apr 2024 · 5,554 accessesView PDFCite
Research ArticleOpen accessIn the abstractClassification of Non-Small Cell Lung Cancer Based on Gene Expression in Cases of Smokers and Non-Smokers using Ensemble Methods with Statistical Based Feature SelectionFhira Nhita, Isman KurniawanLung cancer is one of the leading causes of death globally. One of the main risk factors for lung can ceris smoking, which causes more than 90% of lung cancer cases. There are two types of lung cancer, i.e., Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC), which the latter is the most common. One method that … …Journal of Computer Science, Vol. 18, Issue 10 · 30 Sep 2022 · 6,093 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relevance of Bioinformatic Tools in the Study of Polymorphisms of the B4GALNT2 Gene and its Association with CancerEddaikra Atika, Haddouche Hayet, Touil-Boukoffa ChafiaThe human gene B4GALNT2 encodes an enzyme (β1,4-N-acetylgalactosaminyltransferase II) that controls the expression of the blood group Sda carbohydrate’s antigen. This gene is located in position 17q21,32 and consists of 11 exons. The characterization and understanding of genetic variation is a real challenge in human genetics, both for healthy individuals and diseased ones. The in silico study of the B4GALNT2 … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,767 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Selection-based MCL Clustering Algorithm for Motif DiscoveryChunxiao Sun, Zhiyong Zhang, Jinglei Tang, Shuai LiuAs motif discovery plays an important role in the understanding of the relationship of gene regulation, this paper puts forward a selection-based MCL clustering refinement algorithm (SMCLR) aiming at solving the planted (l, d) motif search (PMS) problem. Firstly, we divide the DNA dataset into different subsets through selection of reference sequence and screen parts of eligible subsets by setting … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 1 Jan 2019 · 8,827 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputing MDR-Game with Applications to Real DataJimbo Henri Claver, Takeru Suzuki, Jesus Pascal et al.Originally developed for probability and statistic purposes, Multiple Dice Rolling (MDR) game turns out to be useful for many other applications such as complex biological systems and medical research. It has been mainly used to estimate system states that cannot be observed directly. MDR game is affected by noise and fluctuations. It is widely agreed that noise in dynamic systems … …Journal of Computer Science, Vol. 14, Issue 7 · 17 Jul 2018 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Efficient Distributed Bioinformatics Computing System for DNA Sequence Analysis on Encoding SystemMohammad Ibrahim Khan, Chotan SheelThis study provides an effective design of search technique of a distributed bioinformatics computing system for analysis of DNA sequences using OPTSDNA algorithm. This system could be used for disease detection, criminal forensic analysis, gene prediction, genetic system and protein analysis. Different types of distributed algorithms for the search and identification for DNA segments and repeat pattern in a given … …Current Research in Bioinformatics, Vol. 2, Issue 2 · 20 Dec 2013 · 6,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Feasibility Study of Challenges and Opportunities in Computational Biology: A Malaysian PerspectiveR. J.A. Richard, N. SriraamThe term computational biology refers to the knowledge derived from a computer analysis of biological data that includes identification of genes in DNA sequence of different organisms, prediction of structural and functional mechanism of proteins, feature extraction and classification of genomics and proteomics. Computational biology is a rapidly developing branch of science and is highly interdisciplinary, using techniques and Concepts … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,924 accessesView PDFCite