2 articles for “Gangrene”

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Case ReportOpen accessEvery word in the titleA Case Report of Severe Malaria Due to Plasmodium falciparum Malaria Complicated by Symmetrical Peripheral Gangrene (SPG) at the Matlaboul Fawzaini National Hospital Center, Touba, SenegalJules Yindoni Zande, Ndeye Fatou Ngom et al.Malaria remains a major public health problem worldwide, particularly in Africa. Symmetrical Peripheral Gangrene (SPG) is a distal ischemic lesion affecting at least two extremities in the absence of proximal arterial obstruction and vasculitis. It is a rare and severe clinical entity. Its association with malaria is rare, with approximately 27 cases reported worldwide, mostly in Asia. A 15-year-old male … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 22 Jan 2026 · 2,806 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of pH on the Conformation and Biological Activity of Clostridium septicum Alpha-toxin, a Pore-forming HemolysinB.M. Hang'ombe, T. Kohda, M. Mukamoto, S. KozakiThe effects of pH on the pore-forming Clostridium septicum alpha-toxin that causes myonecrosis was assessed at pH 5.0, 7.0 and 9.0 by measuring circular dichroism and its biological activity. Incubation of the toxin at pH 5.0 increased the hemolytic activity measured in murine red blood cells. On the other hand, incubation of the toxin at pH 9.0 drastically reduces the … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 6,902 accessesView PDF Cite