3 articles for “GIST”

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Research ArticleOpen accessIn the keywordsImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,245 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Integrated Framework to Predict the Strength of New SMILE Using Graph Attention NetworkSandhi Kranthi Reddy, S. V. G. ReddyMachine Learning (ML) and Deep Learning (DL) have significantly advanced various fields, including healthcare, finance, autonomous systems, and scientific research. In healthcare, these technologies have been widely applied to disease prediction, such as cancer and diabetes. However, the challenge of drug resistance persists, creating a need for more effective drugs. Developing new drugs is a complex, expensive, and time-intensive process, … …Journal of Computer Science, Vol. 21, Issue 10 · 25 Nov 2025 · 2,157 accessesView PDF Cite

Research ArticleOpen accessIn the abstractModelling Knowledge Summarization by Evolving Fuzzy GrammarNurfadhlina Mohd Sharef, Alfian Abdul Halin, Norwati MustaphaSummarized text is a simplified and condensed version of the original text containing highlighted information to help the audience get the gist in a short period of time. Typically, text summarization produces abstract or a paragraph-like outputs by omitting details and irrelevant information. However, the text summary can also be produced in a visualized form, such as a chart, graph … …American Journal of Applied Sciences, Vol. 10, Issue 6 · 10 Jun 2013 · 6,659 accessesView PDF Cite