Research ArticleOpen accessPhrase in the titleCHITOSAN NANOPARTICLES AND THEIR APPLICATIONS IN DRUG DELIVERY: A REVIEWSharare Najafi, Zahra Pazhouhnia, Omid Ahmadi et al.Chitosan is one of the most popular materials in the field of drug delivery due to its adhesivity and biodegradability. Different types of Chitosan based drug carriers have been conceived for various administration routes, such as oral, nasal, transdermal, parenteral, vaginal, cervical and rectal due to its biocompatibility and biodegradability. Chitosan Nanoparticles (NPs) have long been studied as carriers for … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 8 Nov 2014 · 14,775 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAMINO ACID TRANSPORTERS IN DRUG DISCOVERYMariafrancesca Scalise, Lorena Pochini, Michele Galluccio, Cesare IndiveriAdministered drugs interact with membrane transporters of epithelia, Blood Brain Barrier and other districts influencing their delivery and efficacy. Drugs can also be used as inhibitors of transporters involved in human pathology. Drug-transporter interactions are responsible of off-target effects contributing to toxicity. High Throughput Screening technologies increased the potential applications in therapy or in predicting side effects. These strategies will … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 2 Oct 2014 · 7,099 accessesView PDFCite
Research ArticleOpen accessIn the keywordsProperties of Chitosan Nanoparticles Formed Using Sulfate Anions as Crosslinking BridgesMayyas M.A. Al-RemawiProblem statement: The preparation of new simple Chitosan nanoparticle delivery system is very important and could have many applications particularly in pharmaceutical field to be used as a drug delivery system. In this study, the production of robust Chitosan nanoparticles has been developed and characterized by chemical crosslinking using sulfate anions. Approach: Chitosan polymer is considered one of the best … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 28 May 2012 · 9,871 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDevelopment of Curcumin Based Ophthalmic FormulationD. Anjana, K. Anitha Nair, N. Somashekara et al.Problem statement: Ophthalmic drug delivery system has been a major challenge due to the distinctive and unique anatomy of the eye. The use of phytochemicals for the application in ocular disease has not been investigated much, due to poor pharmacokinetics of phytochemical and hence poor therapeutic efficacy. Approach: Curcumin is one such phytochemical known for its medicinal properties, but its … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Feb 2012 · 15,401 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMass Production of Uniformly Sized Air-Filled Poly-Lactic Acid Microcapsules Made from Microbubble TemplatesJay Molino, Svetlana Jojlova, Hirofumi Daiguji, Fumio TakemuraHollow poly(Lactic Acid) (PLA) microcapsules were fabricated using the bubble template method. In this method, microbubbles nucleated inside droplets of a dichloromethane solution of PLA which were located in a continuous phase of poly(vinyl alcohol). PLA-covered microbubbles formed when PLA adsorbed to the bubble surface by physisorption. Then, the coated microbubbles were spontaneously released from the droplet´s interior into the … …American Journal of Applied Sciences, Vol. 16, Issue 7 · 20 Aug 2019 · 7,756 accessesView PDFCite
Review ArticleOpen accessIn the abstractBiosurfactants in the Halal Economy: Sustainable Solutions for Food, Pharma, and BeyondKanokphorn Sangkharak, Suppasil Maneerat, Aem Nuylert et al.Biosurfactants, microbial surface-active compounds, are gaining attention as sustainable, biocompatible alternatives to synthetic surfactants. Their properties, including emulsification, foaming, and antimicrobial activities, enable diverse applications in food, pharmaceutical, and cosmetic industries. With increasing demand for halal-certified products, biosurfactants offer potential as halal ingredients, provided they are produced using compliant strains, substrates, and processing methods. This review examines the production of … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 7 Aug 2026 · 1,142 accessesView PDFCite
Review ArticleOpen accessIn the abstractSelf-Assembly Peptides-a ReviewOlushola Sunday Ayanda, Olusola Solomon Amodu, Cyprian Yameso Abasi et al.Self-assembling of peptides is a spontaneous process by which peptides are self-organized to form well-ordered structures by intramolecular and intermolecular interactions.This process is controlled by the balance of the forces (attractive andrepulsive) within the peptide molecules. Notable methods used for the synthesis of self-assembly peptides are solid-phase synthesis, liquid-phase synthesis,recombinant technology, and the use of external fields. The self-assembled nanostructure-based … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 12 Aug 2022 · 5,739 accessesView PDFCite
Review ArticleOpen accessIn the abstractMechanistic Insights of Actions of Metal Nanoparticles on Multidrug-Resistant BacteriaSeham S. Alzahrani, Hani Mohammed Ali, Mohamed M. AhmedMultidrug-Resistant bacteria (MDR) are the most serious threat to public health. The number of infections caused by resistant strains is on the rise all over the world. At this time, new techniques for developing antimicrobial drugs are becoming necessary. Metallic Nanoparticles (MNPs) in the biomedical field are one of the most promising methods to overcome antibiotic resistance. Nanoparticles have recently … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 22 Jun 2021 · 6,374 accessesView PDFCite
Research ArticleOpen accessIn the abstractFacile Synthesis of AgCl Hollow Nanospheres for Enhanced Photocatalytic PropertiesJing Chen, Yuling Zhao, Xinhui Liu et al.AgCl hollow nanospheres have been synthesized successfully via a hard-template approach using silica nanospheres as hard template for the first time. The phase, size and morphology of the as-prepared AgCl were investigated by X-Ray Diffraction (XRD), Field-Emission Scanning Electron Microscopy (FESEM); which reveals that the cubic AgCl hollow nanospheres with a cell constant a = 5.549 Å are 220 nm … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 3 · 22 May 2015 · 7,350 accessesView PDFCite