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25 articles for “Dengue Virus”
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Research ArticleOpen accessPhrase in the titleQuadratic Discriminant Analysis of Dengue Viruses Disease Incidence in PalembangYulia Resti, Noriszura Ismail, Marieska VerawatyPalembang is classified as a city that has tropical climate with abundant rainfall, even in the driest month. These characteristics indicate that the city has a high potential for the occurrence of dengue virus disease. The areas of incidence of dengue virus disease in Palembang can be classified into five areas; South, Center, North, West and East. The aim of … …American Journal of Applied Sciences, Vol. 14, Issue 5 · 30 May 2017 · 7,478 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDETECTABLE ANTI-DENGUE VIRUS IGM ANTIBODIES AMONG HEALTHY INDIVIDUALS IN OGBOMOSO, OYO STATE, NIGERIAE. K. Oladipo, C. Amanetu, T. A. Gbadero, J. K. OlokeDengue fever is a zoonosis maintained in nature by mosquitoes transmitting virus between non-human primate species, most of which develop clinically in apparent infection. It has been found to be endemic in Africa and beyond. A survey for Dengue virus IgM antibody was carried out in Ogbomoso (urban and rural areas) using Enzyme Linked Immunosorbent Assay (WKEA Med Supplies Corp, … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 3 May 2014 · 7,827 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleSerological Evidence of Recent Dengue Virus Infection Among Febrile Children in a Semi Arid ZoneFaneye Adedayo, Idika Nioma, Motayo Babatunde Olanrewaju et al.Presence of Dengue virus has been established in Nigeria; owing to the severity of this disease and its attendant complications we investigated the presence of this virus serologically in febrile Nigerian children under 5 years of age from Ilorin. Blood samples were tested from 130 children under the age of 5 years for the presence of IgM antibodies against all … …American Journal of Infectious Diseases, Vol. 9, Issue 1 · 1 Feb 2013 · 7,894 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,560 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePatient and Mouse Antibodies against Dengue Virus Nonstructural Protein 1 Cross-React with Platelets and Cause Their Dysfunction or DepletionChiou-Feng Lin, Huan-Yao Lei, Ching-Chuan Liu et al.Thrombocytopenia is a clinical manifestation in dengue virus (DV) infection, yet its pathogenic mechanisms are unresolved. We previously showed that dengue patient sera contained antibodies cross-reactive with platelets. In this study, we demonstrated that the anti-platelet activity of dengue patient sera was due to the antibodies against DV nonstructural protein 1 (NS1). Studies using DV-infected or recombinant NS1-immunized mouse sera … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,321 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Murine Charged Multivesicular Body Protein 2A, CHMP2A Interacts with the 5' and 3' Terminal Regions of Dengue Virus Complementary Minus-strand RNASuchita Chaudhry, Sathyamangalam Swaminathan, Navin KhannaDengue (DEN) viruses, of which there are four distinct serotypes (DEN-1, -2, -3 and –4), belong to the Flaviviridae family. Their ‘plus’ sense RNA genomes contain Non-Translated Regions (NTRs) at their 5’ and 3’ ends. Replication of viral genomic RNA, which takes place in close association with host cell membranes, involves the initial synthesis of the complementary minus sense RNA … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,314 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleIn Silico Analysis of Envelope Dengue Virus-2 and Envelope Dengue Virus-3 Protein as the Backbone of Dengue Virus Tetravalent Vaccine by Using Homology Modeling MethodUsman Sumo Friend Tambunan, Arli Aditya Parikesit, Hendra et al.Problem statement: Dengue fever, which was caused by Dengue virus infection, had became a major public health problem in the tropic and subtropical countries. Dengue virus (DENV) had four serotypes (DENV-1, DENV-2, DENV-3 and DENV-4), based on their immunogenic in the human body. Preventive measure will be necessary to decrease the prevalence of dengue fever, by developing modern vaccine. Approach: … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 3 Sep 2010 · 9,265 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAnti-Prm Antibody as an Autoantibody in Dengue Virus InfectionKao-Jean Huang, Yu-Tien Cheng, Yee-Shin Lin et al.We have reported that anti-prM antibody is an enhancing antibody that enhances DV infection of non-Fc receptor bearing cells by dual specificity. We identified the epitope recognized by this anti-prM antibody, M3, which is located at the a.a.53-67of the prM protein nearby the prM/M cleavage junction and these anti-M3 antibodies could be detected in dengue patients sera. Surprisingly, this anti-prM … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,304 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGeneration of Anti-platelet Autoantibody During Dengue Virus InfectionKao-Jean Huang, Yee-Shin Lin, Hsiao-Sheng Liu et al.Dengue virus infection causes dengue fever, Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Thrombocytopenia is common in dengue fever and is always found in DHF/DSS. The pathogenesis of thrombocytopenia is poorly understood. To further understand the relationship between anti-dengue virus antibody and anti-platelet antibody, we generated monoclonal anti-dengue virus antibodies from the dengue virus infected mice that developed … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,535 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDengue Virus Infection Induced NF-κB-dependent Macrophage Migration Inhibitory Factor ProductionLien-Cheng Chen, Huey-Wen Shyu, Huan-Yao Lei et al.Dengue virus (DV) infection can cause mild dengue fever or severe dengue hemorrhage fever and dengue shock syndrome. Macrophage migration inhibitory factor (MIF) is a cytokine that plays an important role in the modulation of inflammatory and immune responses and serum levels of MIF are correlated with disease severity in dengue patients. However, the mechanism that induces MIF production during … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,290 accessesView PDFCite