2 articles for “Deferasirox”

Research ArticleOpen accessEvery word in the titleEffect of Chromium(VI) on Serum Iron and Removal of its Toxicity by Combining Deferasirox and Deferiprone Chelators in RatsS. Jamil A. Fatemi, Marzieh Iranmanesh, Faezeh Dahooee BaloochThe present research is aimed to characterize the potential efficiency of two chelators after chromium(VI) administration for 60 days following two doses of 15 and 30 mg kg-1 chromium(VI) per body weight daily to male rats. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing chromium(VI) from bood serum … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 30 Oct 2013 · 7,152 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleCombined Chelation Therapy with Deferasirox and Desferrioxamine In Removing Lead from RatsFaezeh Dahooee Balooch, Seyed Jamilaldin Fatemi, Marzieh Iranmanesh, Batool HosseinkhaniThe present study aimed to evaluate the potential efficiency of Deferasirox (DFX) and Desfferioxamine (DFO) as chelating agents in removing lead from rats as a biological model. Two different doses of lead (II) chloride (40 and 80 mg kg-1 body weight) were used for 45 days. After this period, all rats showed toxicity symptoms through loss of hair, greenish mottling … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 24 Sep 2013 · 7,151 accessesView PDF Cite