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11 articles for “Cross-reactivity”

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Research ArticleOpen accessPhrase in the titleSulfa Allergy: Cross-Reactivity Versus Multiple Concurrent AllergiesMuhammad Tariq Shakoor, Samia Ayub, Zunaira AyubAs a medical resident we have always been taught that there is some sort of cross reactivity between sulfonamide antibiotics and nonantibiotic sulfonamides. Even the manufacturer’s package inserts contain a precautionary statement about possible Cross-reactivity. The most common approach to this problem is avoidance of all sulfa containing drugs. However, there are few data supporting this contraindication. Thus we may … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 2 Dec 2013 · 9,629 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,560 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCross Reactivity between Dromedary Whey Proteins and IgG Anti Bovine α-Lactalbumin and Anti Bovine β-LactoglobulinN. Youcef, D. Saidi, F. Mezemaze et al.Problem statement: Our aim was to enhance the data on antigenic properties of dromedary whey proteins. Approach: The identification of the whey proteins was carried by SDS-page and Reversed phase high performance liquid chromatography (RP-HPLC). The cross-reactivity of dromedary whey proteins with IgG anti bovine β-lactoglobulin and anti bovine α-lactalbumin, obtained by immunisation of Balb/c mice, was carried out by … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 7,429 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPOLLEN-FRUIT SYNDROMES: A CASE WITH BIRCH-APPLE-CARROT ASSOCIATIONJ. Minov, J. Karadzinska-Bislimovska, S. Stoleski et al.Subjects with sensitivities to certain pollen can experience oral or systemic allergic symptoms associated with ingestion of various fruits, vegetables and nuts. In this case report a birch-apple-carrot association in 23-year-old man suffering from pollinosis who experienced few episodes of oral allergy syndrome, generalized urticaria and bronchospasm immediately time after ingestion of fresh and cooked apple and carrot is presented. … …American Journal of Immunology, Vol. 10, Issue 2 · 10 May 2014 · 7,168 accessesView PDFCite
Research ArticleOpen accessIn the abstractELISA-Based Development of Functional Antibodies for the Efficient Detection of Mycotoxigenic Fusarium (F. oxysporum and F. circinatum) and Diplodia (D. pinea) SpeciesPhumzile Mkhize, Phetole MangenaFusarium contains the most toxigenic and important fungal pathogens, producing a wide range of mycotoxins that include the more toxic secondary metabolites called fumonisins. This study analyzed the presence of common exo- and mycelium-soluble antigens, purified proteins using reducing SDS-PAGE and the expression of antibodies against different fungal pathogens. The results showed the presence of common antigens between pathogens and … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 18 Nov 2020 · 6,601 accessesView PDFCite
Research ArticleOpen accessIn the abstractCurrent Advances in Zika Virus Transmission: Urgency for Effective Therapeutics and PreventionYash Raj, Swatantra Kumar, Amrita Haikerwal et al.Global emergence of Zika Virus (ZIKV) with prevalent outbreaks has been reported in numerous countries of South America, Central America and the Caribbean region. According to recent World Health Organization (WHO)-ZIKV situation report, 84 countries/territories/subnational areas represented with established mosquito-borne transmission of ZIKV. As of 10 August 2017, cumulative Zika cases and congenital syndrome associated with Zika virus reported by … …American Journal of Infectious Diseases, Vol. 13, Issue 2 · 2 Oct 2017 · 7,798 accessesView PDFCite
Research ArticleOpen accessIn the abstractPatient and Mouse Antibodies against Dengue Virus Nonstructural Protein 1 Cross-React with Platelets and Cause Their Dysfunction or DepletionChiou-Feng Lin, Huan-Yao Lei, Ching-Chuan Liu et al.Thrombocytopenia is a clinical manifestation in dengue virus (DV) infection, yet its pathogenic mechanisms are unresolved. We previously showed that dengue patient sera contained antibodies cross-reactive with platelets. In this study, we demonstrated that the anti-platelet activity of dengue patient sera was due to the antibodies against DV nonstructural protein 1 (NS1). Studies using DV-infected or recombinant NS1-immunized mouse sera … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,321 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunological Evidence for Peptide-Carbohydrate Mimicry with a Group A Streptococcus Polysaccharide-Mimetic PeptideSilvia Borrelli, Rehana B. Hossany, Susan Findlay, B. Mario PintoThe immunogenicity of a peptide-protein conjugate developed by linking a peptide mimic DRPVPY of the Group A Streptococcus cell-wall polysaccharide (GAS-CWPS), to tetanus toxoid (TT) was examined. BALB/c mice were immunized three times subcutaneously following homologous or heterologous prime/boost strategies at 4- or 6- week intervals in two different experiments. DRPVPY-TT, CWPS-TT, heat-killed, pepsin-treated GAS bacteria (with exposed polysaccharide) and … …American Journal of Immunology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractDFT Based Electrophilicity Index and QSAR study of Phenols as Anti Leukaemia AgentFarhan A. Pasha, Hemant K. Srivastava, Yakoob Beg, Pashupati P. singhDensity Functional reactivity indices based QSAR study of 49 phenol derivatives is presented in this paper. Two different models to describe the anti leukaemia activity of phenols have been made. First QSAR model includes molecular properties like molecular weight (Mw), hardness (η), chemical potential (μ), total energy, and electrophilicity index (ω). Various regression models have been made and regression quality … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractLarge Scale Production and Characterization of Anti-Human IgG Monoclonal Antibody in Peritoneum of Balb/c MICEB. Baradaran, J. Majidi, Z. M. Hassan, J. AbdolalizadehMonoclonal antibodies are key reagents that are used in biomedical researches, diagnosis of immunodeficiency diseases such as IgG subclasses deficiency and treatment of diseases like infections and cancers. For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human IgG were injected into the peritoneum of the Balb/c mice which have previously been primed with 0.5 … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,089 accessesView PDFCite