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6 articles for “Comet Assay”
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Research ArticleOpen accessPhrase in the titleIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,196 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleZinc Phosphide Induced DNA Damage in the Blood Cells of Gallus sp. using Comet DNA AssayK. A. Muid, R. M. Shahjahan, R. Begum, R. A. BegumProblem statement: The comet DNA assay is considered a suitable and rapid test for DNA-damaging potential in environmental and biomonitoring studies. Approach: During the study comets were analyzed as a measure of DNA damage to quantify the damage in the blood cells of fowls (Gallus sp.) after exposure to Zinc Phosphide (Zn3P2). Here the potential for DNA strand breaks by … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 1 · 3 Mar 2012 · 8,953 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of the Toxic Effects of Chitosan-Coated Magnetite Nanoparticles on Drosophila melanogasterDoris Vela, Jonathan Rondal, Sofía Cárdenas et al.Nanoparticles are a cause for concern because of their potential toxic effects on human health and the environment. The aim of this study was to assess the toxic effect of chitosan-coated magnetite nanoparticles (11.00±4.7 nm) on Drosophila melanogaster through the observation of hemolymph composition, DNA damage, larval survival and lifespan of flies. Chitosan-coated magnetite nanoparticles were synthesized by co-precipitation method. … …American Journal of Applied Sciences, Vol. 17, Issue 1 · 25 Sep 2020 · 7,882 accessesView PDFCite
Research ArticleOpen accessIn the keywordsToxicological Consequences of Di-N-Butyl-Phthalate (DBP) on Health of Nile Tilapia FingerlingsEhsan H. Abu Zeid, Al Shimaa A. KhalilPhthalic Acid Esters (PAEs) are mainly used in the plastics industry as adhesives and plasticizers. Di-n-Butyl Phthalate (DBP) is one of the important members in the family of PAEs was listed as environmental priority pollutants by the US Environmental Protection Agency. The objective of this study was to evaluate the toxicological consequences in Nile Tilapia Oreochromis niloticus L. fingerlings, exposed … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 8,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Flaxseed Supplementation on Lipid Metabolism, Oxidative Balance and Genetic Damage in GoatsMaria Eugenia Cecchini, Dardo Roma, Franco Magnago et al.Epidemiological evidence indicates that flaxseed reduces oxidative stress and cholesterol levels in blood. In this study we evaluated the lipid profile, oxidation of plasma lipids and genetic damage in goats fed on a diet supplemented with flaxseed. Thirteen adult male goats were split in two experimental groups; one of them was fed on a conventional diet of alfalfa and ground … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 2 · 22 May 2018 · 7,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Garcinia Atroviridis on Oxidative Stress and Atherosclerotic Changes in Experimental Guinea PigsAdel. A. Amran, Zaiton Zakaria, Faizah Othman, Paden MoratProblem statement: Oxidative stress plays a major role in hypercholesterolemia induced atherosclerosis. Garcinia atroviridis has been shown to exhibit antioxidant properties. Approach: The present study aimed to investigate the effect of Garcinia atroviridis on the oxidative stress in guinea pigs fed with high cholesterol diet. Twenty-four male Guinea pigs were divided into four groups. Group I served as control while … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,035 accessesView PDFCite