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20 articles for “Colorectal Cancer”
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Research ArticleOpen accessPhrase in the titleUMPM-Net: A Multimodal Deep Learning Framework for Colorectal Cancer PrognosisK. Muthuchamy, S K. Piramu PreethikaColorectal cancer (CRC) is one of the most common cancers worldwide, for which early prediction of patient outcomes is important for personalised treatment planning and to improve survival. However, current prediction systems are limited in the fact that they are based on single-modality data and cannot capture the complex interactions between clinical, imaging, and genomic factors. To overcome these shortcomings, … …Journal of Computer Science, Vol. 22, Issue 9 · 20 Sep 2026 · 613 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAnalysis of the Clinical Incidence and Correlation between Colorectal Cancer and MicroorganismsKalia Koutouvalis, Pablo Augusto BejaranoIn this single institution retrospective medical record review, patients diagnosed with colorectal cancer from the years 2018-2022 were evaluated to distinguish an associative linear relationship between diagnosed colorectal cancer and a positive result for the presence of an infectious microorganism. A total of 241 patients diagnosed with colorectal cancer accompanied by a test or order placed with the purpose of … …American Journal of Infectious Diseases, Vol. 20, Issue 1 · 27 Jun 2024 · 5,023 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,398 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePatterns of Resection among Patients with Hepatic-Only Metastatic Colorectal Cancer a Single Institution Experience and ReviewK.I. Quintyne, N. O’Leary, O. O’Kelly et al.Problem statement: Hepatic-only metastasis in colorectal cancer is not a rare clinical finding and can account for 30% of cases. However, only 10-25% of cases are suitable for hepatic resection as part of their treatment pathway. We sought to document our own findings by reviewing patients with hepatic-only disease. Approach: A retrospective analysis was designed to include all patients seen … …American Journal of Immunology, Vol. 8, Issue 1 · 5 Apr 2012 · 7,196 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleFeasibility Study: Colorectal Cancer Related Educational Program for Korean AmericansJin Hee Kim, Usha Menon, Laura A. SzalachaProblem statement: The purpose of this study was to assess feasibility and acceptability of Colorectal Cancer (CRC) related educational program, specifically designed to promote Fecal Occult Blood Test (FOBT) completion for Korean Americans aged 50 years and older. Approach: Focus group discussion (N = 9) guided by semi-structured questions was conducted to understand the demand for CRC education and to … …International Journal of Research in Nursing, Vol. 1, Issue 2 · 22 Dec 2011 · 6,904 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleMolecular Analysis of KRAS Mutation Associated with Colorectal Cancer in Iraqi PatientsRehab Subhi Ramadhan, Aola Sabah Ali, Rebah Najah AlgafariThe role of KRAS gene was investigated in manifestation of colorectal cancer in Iraqi patients. A total 40 blood samples were collected during October 2016 to January 2017 from AL-Amal Hospital in Baghdad and 20 blood samples from healthy subjects served as control. Blood samples were collected from subjects of 40-70 years old for both patients and control. The study … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 3 Mar 2018 · 9,024 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDetection and Localization of Anti and Pro-apoptotic mRNA Genes in Human Colorectal Cancer Using in situ RT-PCRMohd. Nazil Salleh, Boo Siaw Shi, Wan Khairuzzaman Wan Ramli et al.Problem statement: Recent studies using conventional Polymerase Chain Reaction have shown that anti-apoptotic (Cyclooxygenase-2, COX-2 and Nuclear Factor-κB, NF-κB) and proapoptotic mRNA (Bax and Bad) are involved in the tumorigenesis of colorectal cancer. The aim of this study was to localize the expression of anti and pro-apoptotic mRNA genes using Reverse Transcription in situ Polymerase Chain Reaction (RT in situ … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,441 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRelationship between Streptococcus gallolyticus Infective Endocarditis and Pre-Neoplastic Colorectal LesionsPau Vilardell, Sergio Moral, Josep Maria Frigola et al.Colorectal cancer is associated with Infective Endocarditis (IE) due to specific gut pathogens, such as Streptococcus gallolyticus subspecies, that use tumor presence as a point of blood entry. However, the association between Streptococcus gallolyticus related IE and pre-cancerous colorectal lesions like dysplastic adenomas is unclear. Seventy-one patients diagnosed with IE who underwent colonoscopy in the extension study during admission were … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 28 May 2021 · 7,131 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAn Effective and Viable DNA Extraction Protocol for FFPE Tissues and its Effect on Downstream Molecular ApplicationSai Sushmitha Kontham, Charles Emmanuel Jebaraj Walter, Manjula Raju et al.Archival Formalin-Fixed Paraffin-Embedded (FFPE) tissues are a readily available source of DNA for retrospective studies including genetic predisposition. FFPE tissues present significant challenges for extraction of pure genomic DNA in adequate amounts due to the harsh fixation conditions and long-term storage associated with samples. The aim of the study is to propose a simple, in-expensive, viable protocol for the extraction … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 24 Mar 2020 · 7,374 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to CarcinomaA.S. Abdulamir, R.R. Hafidh, L.K. Mahdi et al.This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel. Therefore, Fifty colorectal cancer and 14 adenoma patients were involved. The histopathological expression of p53, p21 and Ki-67 proteins was evaluated by immunohistochemistry assay. The results revealed that remarkable overexpression of p53 protein was seen in the tumorous … …American Journal of Immunology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,740 accessesView PDFCite