5 articles for “Chatchanok Loetchutinat”

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Research ArticleOpen accessIn the author namesRelation between Macroscopic Binding Constant and the Anticancer Efficacy of the Bovine Serum Albumin-Quercetin Complex against Drug-Sensitive and Drug-Resistant CellsWinit Choiprasert, Chatchanok Loetchutinat, Nathupakorn Dechsupa, Samlee MankhetkornProblem statement: We have previously analyzed the interaction of BSA with flavonoids by using FRET. In this study, the role of BSA on increasing in solubility and on carrying the quercetin derivatives thus enhanced their anticancer efficacy against drug-sensitive and drug-resistant cells were conducted. Approach: The macroscopic (KD) and microscopic (kd) binding constant of the complexation and the cellular partition … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 8,292 accessesView PDF Cite

Research ArticleOpen accessIn the author namesThe Effect of Phyllanthus taxodiifolius Beille Extracts and its Triterpenoids Studying on Cellular Energetic Stage of Cancer CellsPatiwat Sakkrom, Wilart Pompimon, Puttinan Meepowpan et al.Problem statement: The Multidrug Resistance phenomenon (MDR) is the cause of unsuccessful in cancer chemotherapy. The tradition plant is the population used as the alternative medicine in cancer therapy. Due to, P. taxodiifolius is medicinal Thai plant which is used as diuretic drug which has never been explored as the anticancer activities. Approach: Air-dried powder of P. taxodiifolius leaves and … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 8,750 accessesView PDF Cite

Research ArticleOpen accessIn the author namesAntiproliferative Effects of Alkaloids Isolated from the Tuber of Stephania venosa via the Induction of Cell Cycle Arrest in Mammalian Cancer Cell LinesSirinapa Nantapap, Chatchanok Loetchutinat, Puttinan Meepowpan et al.Problem statement: S. venosa (Menispermaceae) is used in traditional medicine. The constituents of S. venosa belonging to showed remarkable cytotoxic activity. According to previous research, S. venosa contains several alkaloids, such as protoberberine stephanine cyclanoline and N-methylstepholidine, kamaline, (+)-N-carboxamidostepharine, (-)-O-methylstepharinosine, (-)-stepharinosine, aporphine (-)-O-acethylsukhodiamine and oxostephanosine. The chemical and biological investigations of this plant are interesting to bioassay-guided fractionation, particularly Antiproliferative … …American Journal of Applied Sciences, Vol. 7, Issue 8 · 31 Aug 2010 · 8,789 accessesView PDF Cite

Research ArticleOpen accessIn the author namesAnticancer Activities of Styrylpyrone from the Leaves and Twigs of Goniothalamus maewongensis via Cell Cycle ArrestPradit Pradupsri, Chatchanok Loetchutinat, Narong Nuntasaen et al.Problem statement: Goniothalamus maewongensis is one of three new species which are found in Thailand recently. The genus goniothalamus is not only well known for the rich of styrylpyrones but also famous for the potential of biological activities, especially the cytotoxic activity against a number of human cancer cell lines. The phytochemical and biological investigations of this plant are interesting … …American Journal of Applied Sciences, Vol. 6, Issue 12 · 31 Dec 2009 · 8,192 accessesView PDF Cite

Research ArticleOpen accessIn the author namesIdentification and Antiproliferative Activity Evaluation of a Series of Triterpenoids Isolated from Flueggea virosa (Roxb. ex Willd.)Sod Monkodkaew, Chatchanok Loetchutinat, Narong Nuntasaen, Wilart PompimonProblem statement: Medicinal plants derived anticancer were now being subjects of many research groups especially, the secondary metabolite triterpenoids trees which had enormous potential to inspire and influence modern antiproliferative research. The study aimed to investigate the chemical constitution and their potential use as antiproliferative activity of purified compounds derived from F. virosa. Approach: The F. virosa was selected and … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 30 Oct 2009 · 7,626 accessesView PDF Cite