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9 articles for “Brain ischemia”
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Research ArticleOpen accessEvery word in the titleMoringa Oleifera Lam Mitigates Oxidative Damage and Brain Infarct Volume in Focal Cerebral IschemiaWoranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: At present, the therapeutic outcome of cerebral ischemia is still not in the satisfaction level. Therefore, the preventive strategy is considered. Based on the protective effect against oxidative damage of Moringa oleifera Lam. Leaves extract, we hypothesized that this plant extract might protect against cerebral ischemia, one of the challenge problems nowadays. In order to test this hypothesis, … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 3 Aug 2012 · 7,574 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePorcine Brain Extract Attenuates Memory Impairments Induced by Focal Cerebral IschemiaJinatta Jittiwat, Jintanaporn Wattanathorn, Terdthai Tongun et al.Problem statement: Stroke or cerebral ischemia has been recognized as one important problem worldwide. To date, the effectiveness of protective and therapeutic strategies against stroke is still very limited. Therefore, the development of novel strategy is required. Porcine brain is traditional believed to improve brain functions. Recent studies showed that the extract of porcine brain could protect against brain damage … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 14,615 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Curcumin and Physical Training on the Brain and Motor Performance of Rats with Cerebral IschemiaKarine Sthéfany Serpa Amaral Dias, Jonas Augusto Ramos, Bruno Mattiello Gomes et al.Brain ischemia is the second most deadly disease in the world and it has already been proven that mild and moderate physical exercises minimize the deleterious effects of this disease on the brain. Curcumin has also been considered a neuroprotective substance. Therefore, the goal of this study was to evaluate the effects of high-resistance training and curcumin on the brain … …Neuroscience International, Vol. 10, Issue 1 · 25 Apr 2019 · 7,765 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Exercise Prior or After Ischemia on the Density of Neurons and Astrocytes in the Brain of RatsLaila Cristina Moreira Damázio, Raphael Teixeira Rocha Melo, Maira de Castro Lima et al.The aim of this study was to analyse the density of astrocytes and neurons in the motor areas of the cortex, striatum and hippocampus of rats that performed exercise before or after cerebral ischemia. A total of 36 Wistar rats were separated into two groups: One that was subjected to Middle Cerebral Artery Occlusion (MCAO) and the other that underwent … …Neuroscience International, Vol. 5, Issue 2 · 14 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessIn the keywordsNeuroprotection Afforded by GABA Against Oxygen-Glucose Deprivation-Induced Injury in Rat Cortical Brain Slices: An Hormetic Dose-Response EffectLorenzo Ricci, Massimo Valoti, Giampietro Sgaragli, Maria FrosiniThe aim of the present investigation was to assess neuroprotection exerted by GABA (100 nM-100 mM) in rat cortical brain slices subjected to oxygen-glucose deprivation and reoxygenation. Neuronal injury and neuroprotection were assessed by measuring the release of glutamate and lactate dehydrogenase and tissue water content. Results demonstrate that GABA exerted neuroprotective effects according to a U-shaped, hormetic-like, concentration-response curve, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Dietary Kaempferia parviflora on Ischemic Brain Injury in the ratWathita Phachonpai, Sinthuporn Maharun, Supaporn Muchimapura et al.Problem statement: Stroke often causes irreversible neuronal damage and related behavioral deficits. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional plant medicines. We investigated the ability of consuming Kaempferia parviflora extract, a Thai medicinal plant reputed for neuroprotective effects against brain damage, reduced infarct volume and improve neurological … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 20 Mar 2012 · 9,088 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Functional Effect of Kaempferia Parviflora on Ischemic Stroke in RatsWathita Phachonpai, Sinthuporn Maharun, Terdthai Tong-Un et al.Problem statement: Oxidative stress has been implicated as important factors in the pathogenesis of cerebral ischemia-induced behavioral deficits particularly memory. Growing attention is being paid to traditional medicinal plants possessing antioxidant activity, as they have been proved therapeutically/prophylactically fruitful against stroke condition. Present study provides evidence of the neroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, against … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 16 Mar 2012 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Cerebral Ischemia of Passiflora foetidaJintanaporn Wattanathorn, Natcha Sattroopinat, Terdthai Tong-Un et al.Problem statement: Although cerebral ischemia induced by stroke has been regarded as the important problem worldwide, the therapeutic efficacy is still inadequate. Since the free radicals are implicated in the pathophysiology of cerebral ischemia, the prophylactic protection against stroke with neuroprotective agent possessing antioxidant effect has gained much attention. Therefore, this study was designed to determine whether the alcoholic extract … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 16 Feb 2012 · 8,242 accessesView PDFCite
Research ArticleOpen accessIn the abstractCorrelation Between MMP-3, TIMP-3 Expression and Neuronal Apoptosis After Ischemia -Reperfusion Injury in RatesZi Xiaohong, Mutasem Abuhamed, Yuan Yi et al.Matrix metalloproteinases (MMPs) play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis. How MMP3, TIMP3 expression and neuronal apoptosis (Fas, Fas-L and Bcl) may provide detrimental or beneficial actions during the injury and repair processes after cerebral ischemia-reperfusion injury in rates was studied. Adult rats underwent middle cerebral artery occlusion (MCAO) … …American Journal of Immunology, Vol. 3, Issue 2 · 30 Nov 2007 · 7,175 accessesView PDFCite