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9 articles for “Antidiabetic Drug”
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Research ArticleOpen accessIn the keywordsAssessment of Type 2 Anti-Diabetes on Bound Flavonoids of Barringtonia racemosa (L.) Spreng. Kernel in Glucose-Induced Diabetic RatsMusri Musman, Emelda Audina, Fazlia Inda Rahmayani Ratu et al.A study of type 2 anti-diabetes on bound flavonoids fraction from the kernel of Barringtonia racemosa (L.) Spreng. in glucose-induced diabetic rats was performed. This learning aimed to gather scientific information about the possibility to utilize kernel of B. racemosa as a raw material of antidiabetic drug. The antioxidant property of the bound flavonoids was determined by the DPPH scavenging … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 3 · 16 Dec 2017 · 8,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntidiabetic and Antioxidant Potential of Vernonia amygdalina Leaf Extract in Alloxan-Induced Sprague-Dawley RatsFatmawaty Yazid, Nina Bonita Hasanah, Rosmalena et al.The treatment of diabetes mellitus using drug medications have side effects such as weight gain, hypoglycemia, the risk of cardiovascular or all-cause mortality. These limitations have become one reason to use complementary therapy from plant extract, such as Vernonia amygdalina as an antidiabetes. This research aimed to investigate the effect of V. amygdalina leaf extracts as antidiabetic and antioxidant agents … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 23 Nov 2020 · 8,649 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploration of Antidiabetic and Hypolipidemic Activity of Roots of Croton ZambesicusPrakash Kumar, Rahul Kumar, Manoj Kumar Rastogi, Krishna MurtiThe aim of this study was to investigate the potential antidiabetic and hypolipidaemic effects of aqueous and ethanolic extracts of roots of Croton zambesicus in alloxan induced diabetic models to ascertain its pharmacological applicability. The roots of Croton zambesicus were collected, dried and extracted. The phytochemical screening as well as Median Lethal Dose determination (LD50) was done. The ethanolic extract … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 12 Jun 2017 · 7,851 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Quantitative Plant Activity Relationship (QPAR) for Diabetics II Using Genetic AlgorithmSimanta Kumar Nayak, Bikram Kesari Ratha, Payodhar Padhi et al.The present study demonstrates a novel computational approach for Indian Traditional Medicine (ITM) for the effective antidiabetic drug. Indian traditional practitioners are using many natural Herbals for the cure of diabetes. Though many diabetes patients are getting temporarily cured still its cause and effects are unknown due to lack of proper scientific investigation. Individual plant bioactivities have been already investigated … …Journal of Computer Science, Vol. 11, Issue 3 · 1 Apr 2015 · 6,712 accessesView PDFCite
Research ArticleOpen accessIn the abstractAPIGENIN CAUSES BIOCHEMICAL MODULATION, GLUT4 AND CD38 ALTERATIONS TO IMPROVE DIABETES AND TO PROTECT DAMAGES OF SOME VITAL ORGANS IN EXPERIMENTAL DIABETESChowdhury Mobaswar Hossain, Miltu Kumar Ghosh, Bhabani Sankar Satapathy et al.Diabetes mellitus gradually leads to dysfunction and failure of some vital organs specially the eyes, kidneys, pancreas, brain, heart, liver and lungs. The study was aimed to evaluate the antidiabetic potential of apigenin and its mechanistic role in controlling damages of vital tissues in streptozotocin-induced diabetic rats. Streptozotocin-induced diabetic rats were treated with apigenin and glipizide. Various biochemical changes, GLUT4 … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 13 Jan 2014 · 15,675 accessesView PDFCite
Research ArticleOpen accessIn the abstractPeriodic Validation of High Antidiabetic Potentials of Unripe Plantain in Comparison with Glibenclamide and FansidarE. O. Jimmy, M. A. OkonProblem statement: The antidiabetic potentials of aqueous extract of musa paradisciaca (unripe plantain fruit) were investigated in alloxan induced diabetic rats. The extract at a dosage of 120 mg kg-1 produced a significant (p<0.001) reduction in glucose level by 85% on day 7, 78% on day 14, 64% on day 21 and 44% on day 28. Approach: The extract at … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 1 · 22 Mar 2012 · 7,997 accessesView PDFCite
Research ArticleOpen accessIn the abstractInteraction of Aqueous Extract of Trigonella Foenum-Graecum Seeds with Glibenclamide in Streptozotocin Induced Diabetic RatsV. K. Lal, P. P. Gupta, P. Tripathi, A. PandeyProblem statement: Interaction between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Herb traditionally used to decrease glucose concentrations in diabetes could theoretically precipitate hypoglycaemia if taken in combination with conventional drugs. Approach: The present study was undertaken to determine the interaction of Glibenclamide, a Sulphonylurea with Trigonella foenum-graecum seed extract, an herbal … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 31 Dec 2011 · 8,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiological Study on the Effect of Acalypha wilkesiana Leaves Extract on Streptozotocin-Induced Experimental Diabetes in Male MiceAtef M. Al-AttarProblem statement: Diabetes mellitus is a chronic disease that causes serious health complications and it is now one of the most common non-communicable diseases globally. It is the fourth or fifth leading cause of death in most high-income countries and there is substantial evidence that it is epidemic in many economically developing and newly industrialized nations. Recently, there has been … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 74,606 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Anti Plasmodial Activity of Enicostemma littoraleSanket Soni, Sarita GuptaProblem statement: Malaria is a prevalent disease in India. The problem of drug resistance is worsening. Hence, new effective and affordable antimalarial drugs are very much needed. The long-established use of quinine and the more recent introduction of artemisinin as highly effective anti malarials demonstrate that plant species are an important resource for the discovery of new anti malarial agents. … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,707 accessesView PDFCite