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44 articles for “Animal Models”

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Review ArticleOpen accessPhrase in the titleReview of the Progress in Corneal Neovascularization Animal ModelsShuci Tian, Shurong Wang, Yuxi He et al.Corneal Neovascularization (CNV), the extensive growth of blood vessels from conjunctiva into the cornea. It is a sight-threatening condition that can decreases eyesight and even leads to blindness. The pathologic growth of blood vessels impairs light transmission, promotes scar formation and causes inflammations, which harm visual acuity. Abnormal angiogenesis plays an important role in the process of CNV, which may … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 28 Nov 2015 · 8,421 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Antinociceptive Effects of Central and Peripheral Administration of Peganum harmala L. Extracts in Animal ModelsRachida Aboufatima, Loubna Farouk, Mehdi Ait Laaradia et al.The medicinal plant Peganum harmala has been used in traditional Moroccan medicine to accelerate the healing process of various diseases and to relieve the pain. The antinociceptive effect of the Aqueous (AE), Dichloromethane (DE) and Butanolic (BE) extracts of the Peganum harmala L. was tested in mice and rats by chemical and thermal models. Plant seed extracts were given intraperitoneally … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 May 2021 · 6,423 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEvidence of Oxidative Stress in Autism Derived from Animal ModelsXue Ming, Michelle A. Cheh, Carrie L. Yochum et al.Autism is a pervasive neurodevelopmental disorder that leads to deficits in social interaction, communication and restricted, repetitive motor movements. Autism is a highly heritable disorder, however, there is mounting evidence to suggest that toxicant-induced oxidative stress may play a role. The focus of this article will be to review our animal model of autism and discuss our evidence that oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,115 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffects of Bacillus subtilis 'PB6' (ATCC - PTA 6737) on Clostridium difficile Associated Diarrhea (CDAD) and Inflammatory Bowel Disease (IBD) in Animal ModelsEric Peys, Jerry Varghese, Ponusami Suresh et al.The administration of probiotic bacteria is emerging as a potential means of preventing the onset or recurrence of Clostridium difficile associated diarrhea (CDAD) and of attenuating inflammatory activity and preventing relapses in inflammatory bowel disease (IBD). We evaluated the efficacy of Bacillus subtilis 'PB6' (ATCC - PTA 6737) in a hamster model of antibiotic-induced CDAD and in a rat model … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,097 accessesView PDFCite
Research ArticleOpen accessIn the keywordsProduction of an Achillea millefolium (Yarrow) Toothpaste to Combat Gum and Tooth PainMunashe K. F. Chakamanga, Ashley Kumalo K, Dirk Hamadziripi MGum inflammation also known as gingivitis is primarily caused by the accumulation of dental plaque that forms on teeth. The inflammation triggers pain in the gums and surrounding tissues due to increased blood flow and immune activity aimed at combating the bacterial infection. Thus, this study was carried out to investigate the efficacy of Yarrow-based toothpaste in reducing gum inflammation. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 9 Oct 2026 · 420 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnimal Health Prediction Using Hybrid CNN Based BiLSTM Classification Model: A Deep Learning ApproachJ. Rathi, A. SumathiAccurate prediction of animal diseases is vital in veterinary medicine, as it can substantially enhance animal health outcomes and mitigate economic losses, making it a critical task that warrants attention and innovative solutions. This paper proposes a novel approach to animal condition classification, leveraging an Auto-encoder-based feature selection process and an Improved Hybrid Convolutional Neural Networks (CNN) with Bidirectional (Bi-LSTM) … …Journal of Computer Science, Vol. 22, Issue 5 · 20 May 2026 · 1,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnimal Health Prediction Using Hybrid KNN Based Vector Neighbor Classification Model: A Machine Learning ApproachJ. Rathi, A. SumathiAnimal condition disease prediction is a crucial task in veterinary medicine, and accurate prediction can significantly improve animal health and reduce economic losses. This paper proposed a novel hybrid classification model that combines an Improved Fuzzy-based feature selection process with a Hybrid KNN-based Vector Neighbor Classification model to enhance animal condition disease prediction. The proposed model aims to improve the … …Journal of Computer Science, Vol. 21, Issue 9 · 21 Oct 2025 · 2,900 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of the Most Popular Currently Used Murine Models of AtherosclerosisAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis is a widespread and serious problem. Every year it causes a huge number of deaths and morbidity. Many aspects of this disease remain not fully understood, which indicates the need to search for the most representative model of atherosclerosis in animal and cell culture models. Animal models resembling the pathophysiology in humans are needed to study the immunometabolic mechanisms … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 4 Jan 2024 · 4,669 accessesView PDFCite
Research ArticleOpen accessIn the abstractWelfare and Reproductive Performance of Rabbits Under Two Housing Models in the Egyptian Delta RegionKhaled Hassan El-Kholy, Abdel-Monem Abel-Rahman Sedki, Hossam Zakaria Khalil, Ibrahim Talat El-RatelConcerns about animal welfare due to climate change are growing in the rabbit industry and determining an animal's welfare status is important. So, it is necessary to consider housing conditions as one of the main management criteria. The goal of this study was to examine the preference of rabbits under two housing models of various roofing materials. Twenty-four doses and … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 4 · 30 Oct 2023 · 5,254 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite