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25 articles for “Adipose tissue”
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Research ArticleOpen accessPhrase in the titleEffects of Aerobic Exercise on PPAR-γ Expression in Adipose Tissue and RT-PCR Detection AnalysisXiaodong Zhan, Chenguang Bi, Jie WeiThis study aimed to examine the effect of organized aerobic exercise on the expression level of Peroxisome Proliferator-Activated Receptor gamma (PPAR-γ) gene in adipose tissue by performing digital variant of RT-PCR, Droplet Digital PCR (ddPCR) which is a highly sensitive method for counting the gene copy numbers. The proposed scheme consists of three-stage analytical procedure, namely, Subphase I Controlled Aerobic … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 29 Sep 2026 · 580 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Serial Passaging on the Morphology and Biological Characteristics of Human Adipose Tissue-derived Stem CellsLenka Oravcova, Martin Bohac, Lubica Krajciova et al.Somatic stem cells posses an exclusive property of self regeneration and plasticity which makes them promising candidates for use in tissue engineering and regenerative medicine. In the case of stem cell therapy it is crucial to obtain them in sufficient amount. That's why they have to be cultured under in vitro conditions. Long term culture provides adequate number of cells, … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 17 Dec 2016 · 7,242 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Niacin on Hyperleptinemia and Ob Gene mRNA Over-Expression in Adipose Tissue of Dexamethasone Treated RatsTahoora Shomali, Mahnaz Taherianfard, Mehdi Fazeli, Niloofar SafaeiProblem statement: Glucocorticoid-induced ob gene over-expression and resulted hyperleptinemia may lead to adverse consequences especially on cardiovascular system; therefore, the present study was conducted to evaluate the effects of niacin on hyperleptinemia and ob gene over-expression due to dexamethasone administration in rats. Approach: Twenty four adult male rats divided randomly into four equal groups: 1- normal saline (control), 2- dexamathasone … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 7,988 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleSex Dimorphism in the Fgf21 Gene Expression in Liver and Adipose Tissues is Dependent on the Metabolic ConditionNadezhda Bazhan, Tatiana Jakovleva, Natalia Balyibina et al.Fibroblast growth factor-21 (FGF21) beneficially affects carbohydrate and lipid metabolism. Previously, a sex-specific activation of Fgf21 expression was observed in humans and animals with metabolic diseases. It is unknown whether the sex differences in the Fgf21 expression are manifested in response to the natural physiological situations of fasting and refeeding. The aim of this work was to determine liver, White … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 29 Jan 2019 · 8,153 accessesView PDFCite
Review ArticleOpen accessIn the keywordsThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdipokines Overview: The Major Component of Immune DysregulationAnastasia Vladimirovna Poznyak, Daria Dmitryevna Borodko, Stanislav Anatolievich Antonov et al.Purpose of Review: Obesity is increasingly recognized as an immune endocrine disorder rather than only a metabolic condition. This review critically examines how adipokines particularly adiponectin, resistin, adipsin, and chemerin mediate the interplay between obesity and autoimmunity. Unlike previous reviews that broadly surveyed cytokines, our focus is on comparative roles of specific adipokines across multiple autoimmune diseases. Recent Findings: Evidence … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 11 Aug 2026 · 879 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdipose-Derived Canine Mesenchymal Stem Cells in PLAY® MediaArjun Kulkarni, Bhavana N. V., Teena Mary Thomas et al.In veterinary medicine, stem cell-based therapies present promise for addressing orthopedic and degenerative conditions in canines. Mesenchymal Stem Cells (MSCs) possess unique regenerative, immunomodulatory, and differentiation capabilities. However, their efficacy relies on optimal in-vitro conditions. Prolonged expansion over passages leads to a gradual loss of stem cell traits, highlighting the importance of optimized culture conditions and media supplements. This study … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 3 · 13 Jul 2024 · 5,598 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Static Magnetic Field Exposure in Obese Mice Induced by High Fat Diet: Its Effect on T-Box15 Gene and Uncoupling Protein 1 ExpressionWidia Bela Oktaviani, Puji Sari, Luluk Yunaini et al.Increased Ca2+ cytosolic concentration caused by Static Magnetic Field (SMF) exposure modulates Tbx15 protein and Ucp1 gene interaction that is involved in the thermogenesis browning process of white adipose tissue. Activation of Tbx15 as a transcription factor that regulates the expression of the Uncoupling protein 1 (Ucp1) gene induced by SMF exposure in adipose tissue converts excess accumulated fat into … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 23 Jan 2024 · 4,521 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Long Non-coding RNAs Expressed During Early AdipogenesisRongkun Shen, Rachel A. Soeder, Henry D. Ophardt et al.Long non-coding RNAs (lncRNAs) are transcripts with a length of more than 200 nucleotides that lack protein-coding capacity. LncRNAs play important roles in the regulation of genes during many biological processes, development and disease progression, such as obesity. Obesity is an increasing health concern around the world. Although multiple studies linking lncRNAs and fully differentiated adipocytes have been published, the … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 30 Nov 2019 · 7,823 accessesView PDFCite