Research ArticleOpen accessPhrase in the titleActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Silencing of Septin 1 via Synthetic siRNAs in Schizosaccharomyces pombeSemih Ekimler, Merve Yilmazer, Ercan AricanSeptins are evolutionary conserved GTP-binding proteins and form heterooligomers in cells to interact with cytoskeleton. The main roles of septins in cell are cytokines, membrane interactions, vesicle trafficking and microtubule and actin organization. Non-coding RNAs are key players of gene expression regulation. Small-interfering RNAs (siRNAs) belong to non-coding RNAs, are characterized by sequence complementarity to their target mRNAs. siRNAs silence … …OnLine Journal of Biological Sciences, Vol. 17, Issue 1 · 31 Mar 2017 · 7,237 accessesView PDFCite