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199 articles for “ALP”
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Research ArticleOpen accessEvery word in the titleAlpha Thalassemia Carrier Detection a Diagnostic ApproachH. R. Samruddhi, Anupama Hegde, Harsha Prasada L et al.Alpha-thalassemia is one of the most common single-gene disorders, and its carrier state often remains undetected due to nonspecific hematological findings. This study aimed to identify alpha-thalassemia carrier status among people being investigated for hemoglobinopathy in a tertiary care setting. A cross-sectional laboratory-based study was conducted from January 2023 to January 2024. Hemoglobin variant analysis reports by High Performance Liquid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 22 Sep 2026 · 481 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOat Pellets and Hay in Alpacas of Pastures of the Andean Zone, PerúMarcial Enciso Altamirano, Jimny Núñez Delgado, Alejandrina Sotelo-Méndez et al.The research was carried out at the INIA's Quimsachata experimental center in Puno, Peru; with the purpose of evaluating oat pellets and hay in Alpaca pastures in the Andean Zone. A total of Sixty-three 15-month-old female alpacas were used to evaluate their weight gain and feed consumption. The experiment was conducted with three treatments and 21 replicates under a completely … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 4 · 4 Mar 2025 · 5,583 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAlpha Power Inverted Exponentiated Weibull Distribution with Data ApplicationsAbdulkareem M. BasheerA novel extension of the Inverted Exponentiated Weibull (IEW) distribution is achieved through the utilization of the generator Alpha Power (AP) transformation. The resulting extended distribution is denoted as the Alpha Power Inverted Exponentiated Weibull (APIEW) distribution, which encompasses various sub-models. The statistical characteristics of the newly proposed distribution are established, encompassing the hazard rate function, mean residual life, mean … …Journal of Mathematics and Statistics, Vol. 20, Issue 1 · 21 Dec 2024 · 8,370 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytokine Expression During the Early Response of A549 Cells to Infection with Influenza Virus, Alphacoronavirus and BetacoronavirusQian Wen Wang, Jae Kyung KimThe escalating incidence of coronavirus infections underscores the critical need for a comprehensive understanding of the differential impacts of Human Coronaviruses (HCoVs) belonging to the Alphacoronavirus and Betacoronavirus genera. This study investigated the varying effects of HCoV-229E (Alphacoronavirus), HCoV-OC43 (Betacoronavirus), and influenza A virus subtype H3N2 on A549 cell viability and cytokine expression. Results showed that H3N2 triggered a more … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 6 Jul 2024 · 4,554 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Dynamic of Afamin and Alpha-Fetoprotein Expression during Rat Liver DevelopmentIndriyani, Isabella Kurnia Liem, Puspita Eka Wuyung et al.Liver has a high level of Alpha-fetoprotein which is assumed to be important for mammalian development. However, Alpha-fetoprotein knockout studies in mice suggested that despite the absence of Alpha-fetoprotein, mice developed normally; the only abnormality observed was infertility in female mice. There are indications that Afamin, a protein that has a gene sequence located on the same chromosome as Alpha-fetoprotein, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 5 Feb 2021 · 6,766 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTwo Co-Expression Strategies for Eicosapentaenoic Acid Production in Mortierella alpinaXin Tang, Haiqin Chen, Xiaoke Zhang et al.The omega-3 long-chain Polyunsaturated Fatty Acid (PUFA) Eicosapentaenoic Acid (EPA) has beneficial effects on human health, leading to its use in health products and foods. The oleaginous microorganism Mortierella alpina has been used in the industrial production of Arachidonic Acid (AA). The omega-3 desaturase oPpFADS17 is a key enzyme in the bioconversion of AA to EPA from Phytophthora parasitica and … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 5 Dec 2019 · 7,480 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,835 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Fast Hybrid Algorithm Approach for the Exact String Matching Problem Via Berry Ravindran and Alpha Skip Search AlgorithmsAbdulwahab Ali AlmazroiProblem statement: String matching algorithm had been an essential means for searching biological sequence database. With the constant expansion in scientific data such as DNA and Protein; the development of enhanced algorithms have even become more critical as the major concern had always been how to raise the performances of these search algorithms to meet challenges of scientific information. Approach: … …Journal of Computer Science, Vol. 7, Issue 5 · 7 May 2011 · 7,398 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of a Prophylactic Dose of Ibuprofen on Plasma Level of Interleukin 1, Interleukin 6 and Tumor Necrosis Factor-Alpha in a 1500 m Running PracticeGholamreza Sepehri, Mohammad Pourranjbar, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: there are controversies about the effects of anti-inflammatory drugs on exercised induced changes on plasma cytokines in untrained male athletes, so the primary purpose of this study was to measure the influence of a prophylactic dose of ibuprofen use on plasma cytokines during a 1500 m running race. Approach: Subjects were 10 untrained male Medical University students who … …American Journal of Applied Sciences, Vol. 8, Issue 1 · 31 Jan 2011 · 7,886 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Molecular Chaperone, Alpha-Crystallin, on the Heat-Induced Aggregation of Beta-lactoglobulinArezou GhahghaeiAggregation of beta-lactoglobulin occurs mainly via intermolecular disulphide bond exchange. Upon heating, beta-lactoglobulin aggregated which increased with increasing pH. The presence of DTT led to more rapid aggregation and precipitation of beta-lactoglobulin. Alpha-Crystallin prevented the aggregation of heat-stressed beta-lactoglobulin and was a more efficient chaperone at higher pH values. In the presence of DTT, however, alpha-crystallin was a less efficient … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,580 accessesView PDFCite