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10 articles for “β-Amyloid”
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Research ArticleOpen accessEvery word in the titleAnalysis of Plasma Amyloid-Beta and Apolipoprotein E Genotypes as Markers of Alzheimer’s Disease in Healthy Korean AdultsEun Ju Oh, Jung Jae Lee, Bo Kyeung Jung, Jae Kyung KimThe presence of the ApoE4 allele interferes with human Amyloid-Beta (Aβ) clearance and reduces the neuronal damage response, which, in turn, is associated with increased Alzheimer’s Disease (AD) risk. Identifying individuals with the highest genetic risk may aid clinical AD diagnosis and prognosis. However, to the best of our knowledge, no previous study has performed blood-based analysis of ApoE polymorphisms … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 26 Mar 2024 · 4,492 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSCANNING ELECTRON MICROSCOPE IMAGING OF AMYLOID FIBRILSEisuke Takai, Gai Ohashi, Ryuichi Ueki et al.This study demonstrated the applicability of Scanning Electron Microscopy (SEM) for the observation of amyloid fibrils without staining. As model specimens, two types of amyloid fibrils with different shapes and chemical compositions were controllably synthesized from hen lysozyme. The apparent fibril widths in the SEM images were considerably larger than the original diameters analyzed by the conventional techniques of Transmission … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 1 Mar 2014 · 10,330 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAcute Phase Protein Responses in Mice Infected with River Water Contaminated by Pasteurella multocida Type B: 2Mohammed Muqdad Khaleel, Faez Firdaus Jesse Abdullah, Lawan Adamu et al.Animals are predisposed to infections through varieties of ways which activate the innate immune systems at the initial phase of acute infections. Hemorrhagic Septicemia (HS) is a devastating septicemic disease of cattle and buffaloes caused by a particular serotypes of Pasteurella multocida and serotype B: 2 is the most importanta cause of the disease in Asia. Therefore, the present study … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 17 Sep 2013 · 7,756 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAcute Phase Proteins, Lipid Profile and Proinflammatory Cytokines in Healthy and Bronchopneumonic Water Buffalo CalvesSabry M. El-Bahr, Wael M. EL-DeebThe aim of the present study was to evaluate the diagnostic value of Acute Phase Proteins (APP), lipid profiles and proinflammatory cytokines in healthy and bronchopneumonic water buffalo calves. Therefore, sixty water buffalo calves (9±1 month old, 175±15 kg) were divided into two equal groups, the first group represented healthy, control, calves whereas calves of the second group were affected … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,415 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Review of Biochemical Markers for Early Diagnosis of Alzheimer’s DiseaseMeha Fatima Aftab, Rizwana S. WaraichAlzheimer’s disease, the most prevalent type of dementia, affects the life of elderly, to such extent that it impairs the ability to perform routine functions as well. The impairment of normal functions not only affects the patients but the family members as well. It is difficult to make a definitive diagnosis; hence some clinical and psychological tools are used to … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 13,511 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Pathology of Alzheimer Disease Elicits an In Vivo Immunological ResponseDavid J. Bonda, Kate M. Webber, Sandra L. Siedlak et al.The mechanism(s) responsible for the loss of neurons that characterizes Alzheimer disease is incompletely understood. Nonetheless, there is considerable evidence suggestive of immune abnormalities coupled to alterations in blood-brain barrier permeability that likely play a key role in both the etiology and progression of the disease. To examine these issues further, this study was designed to examine the presence of … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,115 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsAtherosclerosis and Alzheimer’s Disease Interconnection: Inflammation, Aβ and MoreAnastasia Vladimirovna Poznyak, Victoria Khotina, Roghayyeh Vakili-Ghartavol et al.Despite being the leading cause of CVD and cardiovascular mortality globally, Atherosclerosis (ATH) remains underdiagnosed and undertreated. The reasons behind Alzheimer’s Disease (AD) also remain unclear and there is currently no cure for it. At present, at least 55 million people are believed to be suffering from the disorder and the figures are expected to grow. At the same time, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 26 May 2024 · 4,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Therapeutic Role of Jasonia Candicans and Jasonia Montana Extracts in the Regression of Alzheimer’s Disease in Experimental ModelHanaa H. Ahmed, Hoda F. Booles, Wagdy K.B. Khalil et al.The present article aimed to investigate the potential role of the ethanolic extracts of the aerial parts of Jasonia candicans and Jasonia montana in management of Alzheimer’s Disease (AD) in experimental model. Supplementation of drinking water AlCl3 (0.3%) for 16 weeks induced AD in male rats with siginifcant increase in brain Acetylcholinesterase (AchE) activity, Tumour Necrosis Factor (TNF-α), Transforming Growth … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,830 accessesView PDFCite
Research ArticleOpen accessIn the abstractButyrate-Mediated Genomic Changes Involved in Non-Specific Host Defenses, Matrix Remodeling and the Immune Response in the Rumen Epithelium of Cows Afflicted with Subacute Ruminal AcidosisLouis Dionissopoulos, Anne Hermen Laarman, Ousama AlZahal et al.Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by butyrate have not been defined. The objective of this study was to define the inflammatory-related genomic changes … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 10 Jan 2013 · 8,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Text Mining Approach for Finding Protein-to-Disease AssociationsHisham Al-Mubaid, Rajit K. SinghDiscovering significant relationships between biological entities from text documents is an important task for biologists in order to develop biological models for research and discovery, especially with the existing gigantic amounts of biomedical documents and the rate at which they are increasing everyday. We propose a new text mining method to extract associations between biological entities from text documents; and … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 7,012 accessesView PDFCite