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Research ArticleOpen accessIn the abstractRisk of Second Non Breast Malignancies (SNBM) in Relation to Brca1 And Brca2 Mutation Status Following Breast-Conserving Surgery and RadiotherapyYoulia M. Kirova, Alain Fourquet, Alexia Savignoni, Brigitte Sigal-ZafraniWomen from hereditary breast cancer families with BRCA1/2 germline mutation are at increased risk for contralateral breast cancer (BC) and for ovarian cancer (OC). It is less clear whether mutation status influences the rate of SNBM other than OC. In addition, little is known on the risk of OC in individuals from hereditary BC families without identified BRCA mutation. Our … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 7,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn Application of Carhart Atom Pairs to Predict Anticonvulsant ActivityAlan Talevi, Julian J. Prieto, Luis E. Bruno-Blanch, Eduardo CastroAbout 50 million people in the world suffer from epilepsy, especially in childhood, adolescence and old age. Available treatment fails to control epilepsy in up to 30% of affected people. In developing countries, however, the amount of patients that do not receive adequate treatment climbs up to 75%. Moreover, the new generation of antiepileptic drugs (AEDs) causes important central and … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Complications of HIV Disease and Substances of AbuseLisa R. Norman, Anil KumarIn the last decade, it has become increasingly apparent that neuropsychological deficits and impairments are associated with HIV infection. Given that antiretroviral therapies have extended the life expectancy of HIV-infected persons, it becomes critical to focus on the physical and mental health of these patients. Understanding the neuropsychology of HIV disease can provide insight into improving mental health, functional capacity … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractTopical Cyclosporine A in Corneal Graft RejectionMahmood Nejabat, Jafar Khoshghadam, Masoomeh Eghtedari, Hamid HosseiniCorneal graft rejection is now the most common cause of graft failure after penetrating keratoplasty. This study was designed to determine whether, addition of 2% topical cyclosporine (CSA) to local and systemic steroids in treatment of endothelial corneal allograft rejection, would improve the outcome. A prospective randomized treatment trial was carried out on 40 consecutive corneal graft recipients, presenting with … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,320 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioceramics for Tissue Engineering Applications-A ReviewSunho Oh, Namsik Oh, Mark Appleford, Joo L. OngThree dimensional (3-D) scaffolds have been explored in an attempt to persuade the body to heal or repair tissues that do not do so spontaneously. Considerable advances in tissue engineering and regeneration have been accomplished over the last decade. However, the material and 3-D scaffolds ideal for optimal regeneration of missing or lost tissues has not been identified. While current … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 10,423 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardiovascular Risk Factors in North Indians: A Case-Control StudyVivek P. Singh, V. Ramesh, Sonal Somvanshi et al.There is no large study from North India which has addressed association of (CAD) in angiographically proven cases with lipid levels and the conventional risk factors. In the present study risk factor assessment was done in 200 consecutive patients admitted for coronary angiography and in 200 age and sex matched controls. We have found that the most important predictor of … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,052 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmpirical Study on Applications of Data Mining Techniques in HealthcareHarleen Kaur, Siri Krishan WasanThe healthcare environment is generally perceived as being ‘information rich’ yet ‘knowledge poor’. There is a wealth of data available within the healthcare systems. However, there is a lack of effective analysis tools to discover hidden relationships and trends in data. Knowledge discovery and data mining have found numerous applications in business and scientific domain. Valuable knowledge can be discovered … …Journal of Computer Science, Vol. 2, Issue 2 · 28 Feb 2006 · 9,841 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Six Stages of the Healthcare Economy-Is Socialized Medicine at the Door? A Historical ReviewEldo E. FrezzaThe healthcare industry, nonexistent a century ago, is now a huge fraction of the U.S. economy and an intricate business with a multitude of legislative problems. This review article will summarize the recent history of the healthcare industry, evaluate how hospitals today make and lose money, and provide a few projections about the future of healthcare in America. The hope … …Journal of Social Sciences, Vol. 1, Issue 4 · 31 Dec 2005 · 7,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory Treatment of Infertility in Men with Elevated Antisperm AntibodiesIvan Bubanovic, Slobodan Kojic, Stevo Najman, Zlatibor AndjelkovicPossible causes of subfertility or infertility in men are still poorly defined, but one important category may be elevated level of antisperm antibodies (ASA) caused by infective and/or autoimmune diseases, as well as injuries of male reproductive system. In this study, blood sera from 45 infertile men of different age with ASA positive ELISA test were examined for the serum … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 8,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractPeriodontal Disease as a Risk Factor for Coronary Artery DiseaseGholamali Najafi-Parizi, Ahmad LoriThere are many risk factors for coronary artery disease (CAD) and periodontal disease (PDD) is a controversial risk factor. The aim of this study was to show the association between CAD and PDD. A case-control study was designed. Sixty one patients that CAD was confirm in them by coronary angiography compared with sixty one patients with normal angiography. PDD was … …American Journal of Applied Sciences, Vol. 2, Issue 11 · 30 Nov 2005 · 6,922 accessesView PDFCite