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90 results for “molecular mechanism”
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Research ArticleOpen accessIn the abstractHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Interventions in AgingSuresh I.S. RattanSingle or multiple exposure to low doses of potentially harmful agents can have a variety of anti-aging and longevity-extending hormetic effects. These hormetic stressors include irradiation, physical activity, food limitation, heat, hypergravity, dietary components and reactive oxygen species. Molecular mechanisms facilitating the hormetic effects are being elucidated and comprise a cascade of stress response and maintenance and repair pathways. Although … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,833 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractMedical Consequences of Drug Abuse and Co-occurring Infections: A Brief ReviewJag H. KhalsaToday substance abuse remains one of the major problems in the world with millions of people abusing legal and illegal drugs. In addition, almost one-third of the world population of 6.7 billion people may also be infected with one or more infections. Both drugs of abuse and infections are associated with enormous burden of social, economic and health consequences. This … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmetine produce Entamoeba histolytica Death by Inducing a Programmed Cell DeathJ.D. Villalba-Magdaleno, R. Rojas, C. Gómez et al.Amoebiasis is a major public health problem in tropical and subtropical countries. Although a number of antiamoebic agents are used for its treatment and the molecular targets of these drugs have been identified, the biochemical and physiological mechanisms that produce trophozoite death are little known. The present study dates the in vitro induction of programmed cell death (PCD) in E. … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,214 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Effects of Recombinant Porcine Somatotropin on Pig Fetal Growth and Metabolism: A ReviewD. Villanueva-García, S. A. Olmos-Hernández, D. Mota-Rojas et al.Prenatal development is mainly dependent on a close interrelation between nutritional supply use and regulation by hormones and growth factors. Mechanisms during early embryonic development are sensitive to manipulation through selected management strategies of the sow and modifications of this strategy may serve as a model for the examination of molecular and cellular events controlling early embryonic growth. The administration … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,626 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordStrigolactones in Plant Stress Adaptation: Mechanisms and Agricultural PotentialHumayra Ferdus, Mahabuba Mostafa, Md. Motaher HossainAbiotic stresses have significant negative effects on the growth, development, and productivity of crop plants, which are critical to global agricultural production and ecosystem stability. Strigolactones (SLs), a family of carotenoid-derived plant phytohormones, have been identified as playing key roles in plant development and adaptive responses to environmental stimuli. Initially recognized as signaling molecules in host-parasite interactions and as symbiotic … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 3 Oct 2026 · 573 accessesView PDFCite
Literature ReviewOpen accessAll words, across the recordClinical Uses and Molecular Aspects of Ozone Therapy: A ReviewAna Paula Pivotto, Fernanda Weyand Banhuk, Izabela Virginia Staffen et al.Ozone was discovered over a hundred years ago and since then, it has been widely used in many areas, with the primary use as a disinfectant in various ways, but with applications in diverse conditions. More recently, the use of ozone has extended to other fronts, using it to treat different pathologies. Extensive studies have shown its effects, as well … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 26 Feb 2020 · 10,871 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordOn Application of Carhart Atom Pairs to Predict Anticonvulsant ActivityAlan Talevi, Julian J. Prieto, Luis E. Bruno-Blanch, Eduardo CastroAbout 50 million people in the world suffer from epilepsy, especially in childhood, adolescence and old age. Available treatment fails to control epilepsy in up to 30% of affected people. In developing countries, however, the amount of patients that do not receive adequate treatment climbs up to 75%. Moreover, the new generation of antiepileptic drugs (AEDs) causes important central and … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,862 accessesView PDFCite