85 results for “Functional Structure”

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Research ArticleOpen accessIn the abstractThe Biology of p21Waf1/Cip1 - Review PaperRenald A. Blundellp21WAF1/Cip1 belongs to the Cip/Kip family of cyclin kinase inhibitors (CKI) (p21Waf1/Cip1, p27Kip1, p57Kip1). p21Waf1/Cip1 was first described as a potent and universal inhibitor of cyclin-dependent kinases (Cdks). Two forms of functionally active p21 has been localized and described: a nuclear and a cytoplasmic forms. In this paper the structures of p21 has been described and as well as it … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,012 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Feasibility Study of Challenges and Opportunities in Computational Biology: A Malaysian PerspectiveR. J.A. Richard, N. SriraamThe term computational biology refers to the knowledge derived from a computer analysis of biological data that includes identification of genes in DNA sequence of different organisms, prediction of structural and functional mechanism of proteins, feature extraction and classification of genomics and proteomics. Computational biology is a rapidly developing branch of science and is highly interdisciplinary, using techniques and Concepts … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,924 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordExtraction Process Optimization and Functional Characteristics of by Papain Solubilized Collagen from Large Yellow Croaker (Pseudosciaena crocea) SkinBiaoshi Wang, Wenfeng Li, Shumin Liu et al.Through collagen extraction from large yellow croaker (Pseudosciaena crocea) skin using an enzymatic method, the extraction optimization and characterization of collagen from raw materials after papain hydrolysis pretreatment are studied. The extraction process was optimized using the response surface methodology in this study. The findings show that the optimal conditions are a ratio (solvent to solid) of 25.0 mL/g, a … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 26 Dec 2023 · 5,553 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordPrediction of a Putative Functional Region in the Human Bax Protein by Computational AnalysisMaría Sánchez-Aguilar, Laurence A. Marchat, Absalom ZamoranoStructural domains are relevant elements for interactions between Bcl-2 family members to regulate apoptosis and cell survival. Although BH1-BH4 domains can be identified by their sequence and selective occurrence in Bcl-2-family members, structural regions have not been entirely determined yet. The functional residues of Bax, the most representative pro-apoptotic protein of the human Bcl-2 family, remain almost unknown. Here, we … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,230 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordIdentification and functional characterization of a novel lysine-rich protein from Entamoeba histolyticaAlka Mehra, Sudha Bhattacharya, Alok BhattacharyaIn an attempt to understand the role of genes with no known function, in the protozoan parasite Entamoeba histolytica, an analysis of the proteome was carried out and a Lysine-Rich protein (KRP) was identified for further study. This protein has a modular structure with four domains and was found to be expressed and localized to the cell surface of E. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,707 accessesView PDF Cite