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92 results for “Drug Resistance”
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Research ArticleOpen accessIn the abstractIn vitro and In vivo Anti-Microbial Effects of Nigella sativa Linn. Seed Extracts Against Clinical Isolates from Skin Wound InfectionsMariam A. Abu-Al-BasalcProblem statement: The developing microbial resistance to the existing anti-microbial agents has become a real challenge and a serious problem facing patients suffering from skin infections. Seeds of Nigella sativa have been used for a long time in folk medicine for the treatment of such infections. Production of new potent agents is urgently needed, especially for hospitals and health centers. … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 8,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of a 4th Generation-Cephalosporin Introduction upon the Incidence of Multidrug-Resistant Gram-Negative Bacteria in a Non-Teaching HospitalGuilherme Henrique Campos Furtado, Luciana Baria Perdiz, Eduardo Alexandrino Servolo MedeirosProblem statement: Antimicrobial resistance is a worrisome situation in hospitals around the world and the misuse of certain classes of antimicrobials has contributed for this situation. Approach: We performed a prospective surveillance study on the incidence of multi-drug resistant bacteria before (phase 1) and after (phase 2) the introduction of a 4th-generation cephalosporin in a non-teaching hospital. Results: There was … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,880 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial and Antioxidant Activities of Typhonium Flagelliforme (Lodd.) Blume TuberSyam Mohan, Ahmad Bustamam Abdul, Siddig Ibrahim Abdel Wahab et al.Problem Statement: Multiple drug resistance in human pathogenic micro organisms has developed due to indiscriminate use of modern antimicrobial drugs generally used in the management of infectious diseases. This increases the importance of exploiting the natural sources instead modern drugs. Approach: The antibacterial and antioxidant activity of different extracts from of Typhonium flagelliforme (L.) Blume tuber (family: Araceae) commonly called … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 10,427 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,962 accessesView PDFCite
Research ArticleOpen accessIn the abstractConsequence on Treatment of TB Patients Affected by HIV/AIDS A Conceptual ResearchSarder N. Uddin, S. J. Hossain, Md. N. Huda et al.Mycobacterium tuberculosis is an ancient malady, which is one of the world’s most wide spread infectious bacterial agents. Fully one-third of the world’s population is already infected with Mycobacterium tuberculosis, with the greatest burden of disease and infection borne by people in developing countries. Tuberculosis disease is still out of control. Alarming spread of Human Immunodeficiency Virus (HIV) and emergence … …American Journal of Infectious Diseases, Vol. 2, Issue 4 · 31 Dec 2006 · 7,023 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacodynamic Comparison of the Carbapenems Against E. coli and Klebsiella spp. Containing Extended spectrum β-lactamasesKathryn J. Eagye, Joseph L. Kuti, David P. NicolauCarbapenems are the treatment of choice for extended-spectrum β-lactamases (ESBLs). Ertapenem is a new member of the carbapenem class, and is often grouped with imipenem and meropenem as a recommended treatment for ESBLs. However, new in vitro data question ertapenem’s inclusion as a first line treatment for these bacteria, suggesting that ertapenem has a lower likelihood of obtaining appropriate pharmacodynamic … …American Journal of Infectious Diseases, Vol. 1, Issue 3 · 30 Sep 2005 · 6,890 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordColistin Resistance among Gram Negative Organisms; an Evolving Problem from Tertiary Care Hospital, Pakistan 2014Tuba Bashir, Altaf AhmedThis Study was design to report the evolving Colistin Resistant Gram Negative Organisms from Pakistan in 2014. From 885 isolates of hospitalized patients, 03 Colistin resistant isolates were reported, 02 were Escherichia coli and 01 was Acinetobacter specie. Colistin of all three isolates was tested by Disk diffusion method, MIC by Phoenix 100 (BD) and E-strip. This report contributes a … …Current Research in Microbiology, Vol. 7, Issue 1 · 15 Mar 2016 · 14,728 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordHerbal Compounds-An Alternative for Multi-Drug Resistant Vibrio CholeraeSabah Perveen, Hotam Singh ChaudharyVibrio cholerae is a causative agent of cholerae, many people dies every year, especially in developing countries around the world. The outbreaks of cholera are responsible for approximately 120,000 deaths annually. Cholera is a self limiting illness; however antibiotics are used as a part of treatment regimen. But at present, the treatment against cholera has become very critical issue worldwide, … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 12 Oct 2015 · 7,261 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordIdentification of Clonal Clusters of Klebsiella pneumoniae Isolates from Chennai by Extended Spectrum Beta Lactamase Genotyping and Antibiotic Resistance Phenotyping AnalysisC. Kamatchi, H. Magesh, Uma Sekhar, Rama VaidyanathanProblem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and spread of plasmid encoded extended spectrum beta lactamases and other genes conferring cross-resistance to other antibiotics. This is of concern due to the increasing cost of antibiotic treatment and the spread of multidrug resistance … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,958 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPrevalence and Antibiotic-Sensitivity of Methicillin-Resistant Staphylococcus aureus (MRSA) in Pyogenic Skin Affections of Animals and HumanMaha I. Hamed, Sylvia O. Ahmed, Doaa S. Sayed, Hossam-Elden M. HassanMRSA infections commonly present as skin and soft tissue infections in man and animals. Treatment usually includes opening of abscess and drainage with or without antibiotic therapy. MRSA is usually resistant to certain antibiotics including methicillin, oxacillin, penicillin and ampicillin. Therefore, the aim of the present study was to investigate the prevalence of MRSA in man and animals with suppurative … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 4 Apr 2019 · 7,193 accessesView PDFCite