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127 articles for “Diabetic”

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Research ArticleOpen accessIn the abstractExploration of Antidiabetic and Hypolipidemic Activity of Roots of Croton ZambesicusPrakash Kumar, Rahul Kumar, Manoj Kumar Rastogi, Krishna MurtiThe aim of this study was to investigate the potential antidiabetic and hypolipidaemic effects of aqueous and ethanolic extracts of roots of Croton zambesicus in alloxan induced diabetic models to ascertain its pharmacological applicability. The roots of Croton zambesicus were collected, dried and extracted. The phytochemical screening as well as Median Lethal Dose determination (LD50) was done. The ethanolic extract … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 12 Jun 2017 · 7,856 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Galactomannan Extracted from Iraqi Lycium barbarum L. Fruits against Alloxan-Induced Diabetes in RatsAdnan J.M. Al-FartosyLycium barbarum L. (Solanaceae) is widely used in Iraqi Ayurvedic medicine for the treatment of diabetes mellitus. The present investigation was done to evaluate the effects of polysaccharide (galactomannan) from Lycium barbarum L. Fruits (GLBF) on serum blood glucose, serum lipid profile and lipid peroxidation and antioxidant defence system in liver and kidney of alloxan-induced diabetic rats. GLBF was found … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 15 Dec 2014 · 7,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE EFFECTS OF ORAL ADMINISTRATION OF DIFFERENT DOSES OF HYDROALCOHOLIC EXTRACT OF SILYMARIN ON STATUS OF SERUM TRACE ELEMENTSJ. Sajedianfard, S. Nazifi, H. A. ShamsaeiIn this research, the effect of oral administration of different doses of hydroalcoholic extract of silymarin on the status of trace elements with antioxidant properties (Se, Cu, Zn, Mn and Fe) was studied. Fifty male rats were randomly used in five groups including healthy control group (treated by saline), diabetic control group (treated by saline) and three diabetic groups that … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 3 · 24 Oct 2014 · 6,646 accessesView PDFCite
Research ArticleOpen accessIn the abstractAPIGENIN CAUSES BIOCHEMICAL MODULATION, GLUT4 AND CD38 ALTERATIONS TO IMPROVE DIABETES AND TO PROTECT DAMAGES OF SOME VITAL ORGANS IN EXPERIMENTAL DIABETESChowdhury Mobaswar Hossain, Miltu Kumar Ghosh, Bhabani Sankar Satapathy et al.Diabetes mellitus gradually leads to dysfunction and failure of some vital organs specially the eyes, kidneys, pancreas, brain, heart, liver and lungs. The study was aimed to evaluate the antidiabetic potential of apigenin and its mechanistic role in controlling damages of vital tissues in streptozotocin-induced diabetic rats. Streptozotocin-induced diabetic rats were treated with apigenin and glipizide. Various biochemical changes, GLUT4 … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 13 Jan 2014 · 15,680 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Streptozotocin-Induced Hyperglycemia on the Progression of Hepatocarcinogenesis in RatsChowdhury Mobaswar Hossain, Bhabani Sankar Satapathy, Laboni Mondal et al.Diabetes mellitus and hepatocellular carcinoma both have detrimental impact on health worldwide. Type II diabetes and liver cancer share many causative factors, but biological correlation between the two diseases still remains elusive. The study was aimed to evaluate the effect of induction of diabetes during the development of hepatocarcinogenesis in rats. Rats were divided into four groups namely, normal control, … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 4 Nov 2013 · 7,521 accessesView PDFCite
Research ArticleOpen accessIn the abstractStatin Therapy in the Management of Diabetes Mellitus; How Relevant?Fasanmade Olufemi Adetola, Odeniyi Ifedayo AdeolaDiabetes is associated with the development of premature cardiovascular disease. There have been many clinical trials of statin treatment conducted in patients with Coronary Heart Disease (CHD). Taking a closer look at the subset of those patients with diabetes mellitus puts no doubt on the beneficial effect of lowering cholesterol with statin in these patients. Earlier studies done dwell more … …Current Research in Medicine, Vol. 4, Issue 1 · 25 Mar 2013 · 7,869 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa oleifera Leaves Extract Attenuates Neuropathic Pain Induced by Chronic Constriction InjuryJurairat Khongrum, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Problem statement: Neuropathic pain, a challenge of this decade, has been reported to be associated with the diversity conditions including diabetes. At present, there are no conventional analgesics that can effectively treat neuropathic pain with a satisfactory outcome. Due to the limitation of therapeutic efficacy, the searching for novel effective remedies in the management of neuropathic pain is required. Approach: … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 18 Jun 2012 · 17,253 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Resistance of Community and Hospital Acquired Methicillin-Resistant Staphylococcus aureus Isolates from Clinical SpecimensAza Bahadeen Taha, Sabria M. Said Al-SalihiProblem statement: Methicillin-Resistant Staphylococcus aureus (MRSA) is responsible for an increasing number of serious hospital and community acquired infections. Increased emergence in MRSA resistance to antibiotics is a growing problem. Approach: The resistance of MRSA to 20 antibiotics agents were studied. Also comparison of antibiotics resistance of community and hospital acquired MRSA were performed. Meanwhile the profile of antibiotics resistance … …Current Research in Medicine, Vol. 2, Issue 2 · 4 Oct 2011 · 7,885 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiological Study on the Effect of Acalypha wilkesiana Leaves Extract on Streptozotocin-Induced Experimental Diabetes in Male MiceAtef M. Al-AttarProblem statement: Diabetes mellitus is a chronic disease that causes serious health complications and it is now one of the most common non-communicable diseases globally. It is the fourth or fifth leading cause of death in most high-income countries and there is substantial evidence that it is epidemic in many economically developing and newly industrialized nations. Recently, there has been … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 74,650 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of Adiponectin Receptors in Human Placenta and Its Possible Implication in Gestational DiabetesNaglaa Fathy Al Husseini, Mosaad M. Odaa, M.A. Mohamed et al.Problem statement: Similar to obese patients and type 2 diabetic patients, adiponectin levels are reduced in former Gestational Diabetes Mellitus (GDM) patients and are lower in GDM women during late pregnancy compared with pregnant control subjects matched for BMI. Diabetic insult at later stages in gestation, such as may occur in gestational diabetes, will foremost lead to short-term changes in … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 8,199 accessesView PDFCite