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117 results for “Antibody”
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EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,629 accessesView PDFCite
Case ReportOpen accessIn the abstractEpistein-Barr Virus Infection with Concurrent Pancreatitis and Hepatitis: A Rare Disease EntityJered Cook, Megha Kothari, Andrew NguyenConcurrent acute hepatitis and acute pancreatitis is a rare disease entity. Most commonly it can be attributed to infectious etiologies such as hepatitis A, Hepatitis B and Hepatitis E. Although not as common, Epstein Barr Virus (EBV) should be considered in the differential diagnosis in patients with combined hepatitis and pancreatitis. We report a case of a 25 year-old male … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 18 Sep 2015 · 7,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractMOLECULAR CHARACTERIZATION ON THE BASIS OF HA, NA AND M GENE REVEALED CHANGES IN CRITICAL AMINO ACID POSITIONS OF INFLUENZA A (H3N2) VIRUS CIRCULATING IN INDIA DURING 2011-2013Sachin Kumar, Shashi Khare, Bano Saidullah et al.Influenza a (H1N1) virus is responsible for acute respiratory infection in human, which occasionally causes epidemic and rarely a pandemic. Full length DNA sequencing of HA, NA and M gene of H3N2 virus from year 2011-2013 was performed for determination of the circulating strains in India along with monitoring status of various mutations associated with drug resistance and virulence. Genetic … …American Journal of Infectious Diseases, Vol. 10, Issue 3 · 18 Oct 2014 · 6,842 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractDETECTABLE ANTI-DENGUE VIRUS IGM ANTIBODIES AMONG HEALTHY INDIVIDUALS IN OGBOMOSO, OYO STATE, NIGERIAE. K. Oladipo, C. Amanetu, T. A. Gbadero, J. K. OlokeDengue fever is a zoonosis maintained in nature by mosquitoes transmitting virus between non-human primate species, most of which develop clinically in apparent infection. It has been found to be endemic in Africa and beyond. A survey for Dengue virus IgM antibody was carried out in Ogbomoso (urban and rural areas) using Enzyme Linked Immunosorbent Assay (WKEA Med Supplies Corp, … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 3 May 2014 · 7,836 accessesView PDFCite
Research ArticleOpen accessIn the abstractISOLATION AND DETECTION OF HELICOBACTER PYLORI FROM PATIENTS SUFFERING FROM PEPTIC ULCER USING BIOCHEMICAL TESTS AND MOLECULAR TECHNIQUESRuba S. Abu-Sbeih, Azmi D. Hawari, Dhia S. Hassawi, Hala I. Al-DaghistaniHelicobacter pylori is the causative agent of most cases of gastritis. There is no established gold standard for the diagnosis of H. pylori infection. A reliable diagnosis is crucial to confirm that eradication therapy has been successful. Eighty gastric biopsy and blood samples were obtained from fasting Jordanian patients with Esophago-Gastro-Doudenoscopy (EGD). Several diagnosis tests for H. pylori infections were … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 28 Mar 2014 · 8,185 accessesView PDFCite
Research ArticleOpen accessIn the abstractPHENOTYPING, VIRULENCE CHARACTERISTICS OF AEROMONAS SPECIES AND THE EFFECTS OF ESSENTIAL PLANT OILS AS ANTIMICROBIAL AGENTS AGAINST PATHOGENIC ISOLATES FROM DIFFERENT SOURCESAhmed M.A. Mansour, Hoda M. Zaki, Nibal A. Hassan, Nihad A.M. El-NasharAeromonas species are increasingly recognized as enteric pathogens. Faecal samples from 20 cow, 45 sheep; 60 goat and 60 camels were examined for the presence of Aeromonas species, which was also sought in the available drinking water (55 well water and 52 drinking chlorinated tap water were also examined). Aeromonas species was isolated more frequently from goats (21.7%) than from … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 18 Jan 2014 · 8,024 accessesView PDFCite
Research ArticleOpen accessIn the abstractPRODUCTION OF CROSS-REACTIVE AUTOANTIBODY BINDING TO BOVINE SERUM ALBUMIN IN THE D-GALACTOSE-INDUCED AGING MOUSE MODELJi-Hun Park, Tae-Saeng ChoiThe D-galactose (D-gal)-induced animal model, generated by repeated subcutaneous D-gal injections over approximately 6 weeks, has been frequently used for diabetes and aging research. However, little research has investigated the direct correlation between D-gal and autoantibody formation despite several reports on diabetes-and aging-related autoantibodies. The purpose of this study was to determine whether repetitive injection of D-gal can induce autoantibody … …American Journal of Immunology, Vol. 10, Issue 1 · 13 Jan 2014 · 7,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,840 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvolvement of Bone Marrow Megakaryocytes in the Formation of the Bone Marrow-Blood Barrier in Transgenic MicePawel Laskowski, Karol Ostrowski, Beata Klim et al.Mature cell release takes place through the hypothetical barrier- the bone marrow-blood barrier. It consists of blood vessels and cells that surround them. Such cells are, among others, megakaryocytes. They are involved in the release of platelets or other cellular components of blood. The amount and the development of megakaryocytes and thus the maturity of barrier depends on many factors. … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 19 Sep 2013 · 7,185 accessesView PDFCite