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Research ArticleOpen accessIn the abstractAT1-IR-beta Association: A New Mechanism for the Inhibition of Insulin Receptor Function in Breast CancerLakshmi Pulakat, Ravindra Kolhe, Nara GaviniEpidemiological evidence show that increased mortality in breast cancer is linked to hypertension and insulin resistance. Because Angiotensin II (Ang II), a hormone implicated in hypertension and insulin resistance, is a normal mitogen for breast tissue and elevated expression of the Ang II receptor AT1 is seen in breast cancer, we analyzed the effects of Ang II exposure on the … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 1 · 31 Mar 2008 · 7,019 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relationship Between Location and Prognosis in Brain-Stem TumorsN. Fayed, P. J. Modrego, J. EirasThe objective of this study was to establish a correlation between histopathology and radiological characteristics as well as location of brain stem tumors. Results of therapy were also analysed in relation to the radiological characteristics. Forty four patients were evaluated from a clinical and neuroradiological viewpoint (CT and MRI). In 14 of them we ruled out a surgical therapy. However … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 6,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of Bacterial Strains Isolated Through Microbial Profiling of Urine SamplesPoulomi Nandy, A. R. Thakur, S. Ray ChaudhuriThe present study was conducted to determine the microbial profile in urine samples. Differential and selective chromogenic culture media were used for the rapid detection, identification and enumeration of urinary tract pathogens namely, E. coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecalis, Proteus mirabilis. Urine samples of normal healthy individuals as well as patients with Urinary Tract Infection (UTI) … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 31 Dec 2007 · 7,563 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessIn the abstractHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,493 accessesView PDFCite
Research ArticleOpen accessIn the abstractArabic Speech Pathology Therapy Computer Aided SystemZ. A. Benselama, M. Guerti, M. A. BencherifThis article concerns a computer aided pathological speech therapy program, based on speech models such as the hidden Markov model and artificial intelligence networks, in order to help persons, suffering from language pathologies, follow a correction learning process, with different interactive feedbacks, aiming to evaluate the degree of evolution of the illness or the therapy. We dealt with the Arabic … …Journal of Computer Science, Vol. 3, Issue 9 · 30 Sep 2007 · 6,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of Cholesterol Esterification Influences Cytokine Exspression in Lypopolisaccharide-activated P388D1 MacrophagesRosa Rita Bonatesta, Francesca Sanna, Sabrina Uda et al.Several in vivo and in vitro studies have demonstrated the involvement of infectious agents in the development of atherosclerosis. However, the mechanisms by which micro-organisms induce and/or aggravate atherosclerosis, are so far unclear. Accumulation of cholesterol esters and lipid laden cell formation are hallmark of the atherogenesis, however, the possible relationship between cholesterol esterification and the signal-transducing component of LPS … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 7,484 accessesView PDFCite
Research ArticleOpen accessIn the abstractStandard Versus Specific Therapy for Chronic Osteomyelitis TreatmentAngela Ingianni, Giorgio Lampis, Samuela Laconi et al.58 patients with chronic osteomyelitis were treated either with a standard therapy or with a specific targeted therapy based on the antibiogram assay. Standard therapy was performed by a 15-day course of a parenteral cephalosporin (usually ceftriaxone) in combination with an aminoglycoside (e.g. netilmicin), followed by oral therapy with a fluoroquinolone (generally ciprofloxacin) for 1 to 3 months; specific therapy … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,879 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Novel Chromosomal Abnormalities, inv(5)(p13q13) and t(7;18)(q32;q21), Associated with AutismZheng Chen, Xiao-bing Zou, Ya-nan Zhang et al.Autism is a neurodevelopmental disorder defined by impairments in social interaction, communication, as well as restricted and stereotyped behaviors. While the etiology of autism remains largely unknown, the existence of genetic components has been clearly demonstrated in autistic pathogenesis. The incidence of autism is 50-100 fold greater in the population with autistic family history than the general population. Chromosomal abnormalities … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 6,776 accessesView PDFCite
Research ArticleOpen accessIn the abstractSystem Interoperability Study for Healthcare Information System with Web ServicesJ. K. Zhang, W. Xu, D. EwinsThis paper describes the use of a new distributed middleware technology ‘Web Services’ in the proposed Healthcare Information System (HIS) to address the issue of system interoperability raised from existing Healthcare Information systems. With the development of HISs, hospitals and healthcare institutes have been building their own HISs for processing massive healthcare data, such as, systems built up for hospitals … …Journal of Computer Science, Vol. 3, Issue 7 · 31 Jul 2007 · 6,702 accessesView PDFCite