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Research ArticleOpen accessIn the abstractOpiates Upregulate Adhesion Molecule Expression in Brain MicroVascular Endothelial Cells (BMVEC): Implications for Altered Blood Brain Barrier (BBB) PermeabilityMadhavan P.N. Nair, Supriya D. Mahajan, Jessica L. ReynoldsThe blood-brain barrier (BBB) is an intricate cellular system composed of vascular endothelial cells and perivascular astrocytes that restrict the passage of immunocompetent cells into the central nervous system (CNS). Expression of the adhesion molecules, intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on brain microvascular endothelial cells (BMVEC) and their interaction with human immunodeficiency virus (HIV-1) … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,614 accessesView PDFCite