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Research ArticleOpen accessIn the abstractAnticonvulsant Effect of Pitavastatin in Mice Induced by PentylenetetrazoleKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality by their lipid-lowering actions. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels. The aim of this study was to evaluation the effect of intraperitoneally injection of different doses of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,507 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,679 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impact of Air Pollution on Human Health: Focusing on the Rudnyi Altay Industrial AreaVitaliy G. Salnikov, Marat A. KaratayevProblem statement: Air pollution in Kazakhstan is significant environmental problem. The air pollution level of cities and industrial centers remains rather high. The highest level of air pollution is registered in Ridder, Ust-Kamenogorsk, Almaty, Zyryanovsk, Aktau, Atyrau, Shymkent, Taraz, Petropavlovsk and Temirtau. The enterprises of the Rudnyi Altay, Pavlodar Oblast and enterprises of oil and gas complex in West-Kazakhstan, Atyrau … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 21 Jul 2011 · 10,447 accessesView PDFCite
Research ArticleOpen accessIn the abstractMalaria and Climate Change: Discussion on Economic ImpactsMd. Shahin Mia, Rawshan Ara Begum, Ah-Choy Er et al.Problem statement: Climate change is a global environmental change that is adversely affecting human health by causing various health impacts in countries throughout the world. Climate is the most influential driving force of vector-borne diseases such as malaria. Changes in climate factors substantially affect reproduction, development, distribution and seasonal transmissions of malaria. Climate change increases the outbreak of malaria which … …American Journal of Environmental Sciences, Vol. 7, Issue 1 · 28 Feb 2011 · 6,584 accessesView PDFCite
Research ArticleOpen accessIn the abstractCerebrospinal Fluid (CSF) Ferritin for Differentiation of Aseptic and Bacterial Meningitis in AdultsZhinous Bayat Makoo, Nagmeh Ahadi, Akbar Hasani et al.Problem statement: Bacterial meningitis is one of the most important causes of mortality and morbidity. Rapid diagnosis of bacterial cause is very important and critical, because early antibiotic therapy prevents complications; different tests have been developed for rapid diagnosis of bacterial meningitis. One of them is CSF ferritin, which is evaluated in this study. Approach: During cross sectional study from … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 8,046 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Hematological and Alternate Markers in Human Immunodeficiency Virus Disease ProgressionK. V. Ramana, Jagadeeshwara Chary, V. Sabitha et al.Problem statement: The knowledge of HIV infection has expanded tremendously which has led to significant improvement in the treatment, leading to decrease in morbidity and mortality. Considering the limitations in using CD4+T-cell counts and HIV RNA viral load as markers in the HIV disease progression, physicians treating the HIV patients now look for alternate markers that predict HIV disease progression … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,372 accessesView PDFCite
Research ArticleOpen accessIn the abstractSepticemia: The Principal Killer of Burns PatientsB. R. Sharma, Virendar Pal Singh, Sumedha Bangar, Neha GuptaBurn injury is a major problem in many areas of the world and it has been estimated that 75% of all deaths following burns are related to infection. Burns impair the skin’s normal barrier function thus allowing microbial colonization of the burn wounds and even with the use of topical antimicrobial agents, contamination is almost unavoidable. It is therefore essential … …American Journal of Infectious Diseases, Vol. 1, Issue 3 · 30 Sep 2010 · 7,022 accessesView PDFCite
Research ArticleOpen accessIn the abstractBusiness Continuity Planning: Are We Prepared for Future DisastersNaill M. MomaniProblem statement: Natural and man-made disasters could cause a lot of monetary, mortality and morbidity losses for our business’ operations such as: Activities, products and services. In order to minimize losses from such disasters, it is essential to prepare and implement effective business continuity plans that could deal with abnormal conditions. Approach: In this study, a discussion of the major … …American Journal of Economics and Business Administration, Vol. 2, Issue 3 · 30 Sep 2010 · 7,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial Activity of Marine Source Extracts Against Multidrug Resistance OrganismsNagi A. AL-Haj, Nurmas I. Mashan, Mariana N. Shamsudin et al.Problem statement: Antimicrobial resistance is the major problem of global dimensions with a significant impact on morbidity, mortality and healthcare-associated costs. The problem has recently been worsened by the steady increase in multiresistant strains and by the restriction of antibiotic discovery and development programs. Methicillin-resistant Staphylococcus aureus, pseudomonads and Escherichia coli are a major nosocomial and community-acquired pathogens for which … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 10,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractBrain Abscess Complicating an Intracranial HemorrhageM.D. Vikramjit Mukherjee, M.D. Maria Elena RuizProblem statement: A brain abscess presenting after an Intracranial Hemorrhage (ICH) is an extremely rare occurrence. Diagnosis in this setting is difficult, given the absence of key clinical features, such as neurologic deficit and headaches. Since a delay in the diagnosis of a brain abscess leads to poor outcomes, there should be a high index of suspicion for abscess in … …American Journal of Infectious Diseases, Vol. 6, Issue 2 · 30 Jun 2010 · 7,548 accessesView PDFCite