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100 results for “Protective Effect”
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Research ArticleOpen accessIn the abstractASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractPOTENTIAL AMELIORATIVE ROLE OF N-ACETYLCYSTEINE AGAINST TESTICULAR DYSFUNCTION INDUCED BY TITANIUM DIOXIDE IN MALE ALBINO RATSAhmed Farag El-Kirdasy, Mohamed Abdo Nassan, Ahmed Abdel Aziz Baiomy et al.In this study, we examined the ameliorative action of N-Acetylcysteine (NAC) against Titanium Dioxide (TiO2) induced testicular degeneration in albino rats. Adult male albino rats were given saline as a control group, TiO2 (1200 mg kg-1 BW), NAC (100 mg kg-1 BW) and co-treatment of NAC and TiO2 as a protective group for 3 months. Testicular tissues were extracted for … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 31 Dec 2013 · 7,900 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Virgin Olive Oil (Olea europea. L) on Kidney Function Impairment and Oxidative Stress Induced by Mercuric Chloride in RatsYoucef Necib, Ahlem Bahi, Sakina Zerizer et al.The study was designed to investigate the possible protective role of virgin olive oil in mercuric chloride induced renal stress, by using biochemical approaches. The effects of virgin olive oil on mercuric chloride induced oxidative and renal stress were evaluated by serum creatinine, urea and uric acid levels, kidney tissue lipid peroxidation, GSH levels, GSH-Px and GST activities. Administration of … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 16,786 accessesView PDFCite
Research ArticleOpen accessIn the abstractVitamin E Mitigates Chronic Chlorpyrifos-Induced Oxidative Changes in Pituitary Glands and Testes in Wistar RatsM. Shittu, J. O. Ayo, S. F. Ambali et al.Problem statement: The sperm counts of men have declined by about 50% in the last few decades. The contribution of environmental contaminants to this decline cannot be overemphasized. Pesticide is one of the most pervasive environmental chemical contaminants that have been of increased use due to the compelling need to feed the ever-growing world human and animal population and protect … …American Journal of Applied Sciences, Vol. 9, Issue 1 · 19 Nov 2011 · 7,309 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of in vivo Antioxidant and Hepatoprotective Activity of Portulaca oleracea L. against Paracetamol-Induced Liver Toxicity in Male RatsMohamed H. AhmidaProblem statement: Oxidative stress plays a major role in paracetamol induced hepatotoxicity. Portulaca oleracea (P.O.) has been shown to exhibit antioxidant properties. The present study aimed to investigate the effect of P.O. on the oxidative stress in Paracetamol-induced hepatic toxicity in male rats. Approach: Forty male rats were divided into four groups. Group I served as control; Group II Received … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 7,327 accessesView PDFCite
Research ArticleOpen accessIn the abstractNasal Administration of Quercetin Liposomes Improves Memory Impairment and Neurodegeneration in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Supaporn Muchimapura, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the development of protective strategy against Alzheimer’s Disease (AD) is increasing its importance due to the high prevalence of AD, a limitation of therapeutic efficacy and its high impacts on economic and social aspects. The development of the preventive and therapeutic strategy to protect against the path physiology induced by free radicals in AD from antioxidant … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 7,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of N-Acetylcysteine on Auditory Brainstem Response Threshold Shift in Rabbits Exposed to Noise and Carbon MonoxideSeyedbagher Mortazavi, Masoud Motalebi Kashani, Ali Khavanin et al.Problem statement: Noise Induced Hearing Loss (NIHL) is one of the most important occupational disease in worldwide. NIHL has been found to be potentiated by simultaneous Carbon monoxide (CO) exposure. Exposure to noise plus CO is common in occupational and environmental settings. Free radicals have been implicated in cochlear damage resulting from exposure to noise and due to CO hypoxia … …American Journal of Applied Sciences, Vol. 7, Issue 2 · 28 Feb 2010 · 8,040 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstimation of Naturally Modified Mineral Water Protection Activity Against Experimental InfectionsEdward Vladimir Krizhanovsky, Kwong Choong LimAn estimation of protective efficiency of naturally modified mineral water (BAE Synergy Liquid preparation) was performed on animals in models of flue and anthrax infections. The preparation exhibited a significant effect as a preventive and therapeutic agent at these infections. …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,873 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of Oral Contraceptives and Abnormal Pap SmearSayedmohsen Sayednozadi, Mohammadreza Hassany, Mohammad Arash RamezaniTo assess the hypothesis that combined Oral Contraceptive (OCs) increase the risk of cervical neoplasia, we conducted a multicenter Case-Control study in Mashhad, the capital of Khorasan province. Seventy-eight women with moderate to severe dysplasia at Pap smear as case group and one hundred fifty nine women with normal Pap smear were selected as the control group for evaluation. The … …American Journal of Applied Sciences, Vol. 2, Issue 7 · 31 Jul 2005 · 6,772 accessesView PDFCite