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Research ArticleOpen accessEvery word in the titleCryptococcosis Neuro-Brain in 42 Patients at the University Hospital of BrazzavilleOssibi Ibara Bienvenu Rolland, Mabiala Babela Jean Robert, Attinsounon Cossi Angelo et al.To describe epidemiological, clinical, therapeutic; and evolutionary aspects of Neuromeningeal Cryptococcus (NMC) at Brazzaville University Hospital and to find out factors associated to death. A descriptive and analytical retrospective study of NMC files in the infectious diseases department between January 1 and December 31, 2013. 973 patients were hospitalized, 42 NMC cases (4.3%) were compiled. The mean age was 40.2±10.4 … …American Journal of Infectious Diseases, Vol. 13, Issue 4 · 2 Mar 2018 · 7,411 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleQuantitative Analysis of Hypothalamic Proline-Rich Peptide-1 in Blood Serum of Patients with Malignant TumorsNarine Tumasyan, Silva Abrahamyan, Nune Kocharyan et al.The proline-rich-peptides are a class of neurosecretory hypothalamic bioactive polypeptides derived from cattle and comprise the content of bovine posterior pituitary neurosecretory granules. These peptides are co-validated through a single precursor protein neurophysin-vasopressin-associated glycoprotein. Proline-Rich-Polypeptide-1 (PRP-1) is a 15-amino acid peptide with anti-neurodegenerative, immunoregulatory, hematopoietic, antimicrobial, and antitumor activity. The aim of this study, accordingly, is to elaborate an assay … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 27 Nov 2025 · 2,287 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCorrelation of Some Biochemical Parameters between Serum and Saliva of Patients with Breast CancerOmar Atrooz, Huthaifa TarawnehRegular breast cancer laboratory examination of serum is aburden on patients, therefore understanding salivary test methods' featuresand limits is important for diagnosis. The study aims to evaluate thebiochemical parameters in the serum and saliva of breast cancer and controlindividuals. Furthermore, to investigate the correlation between two biofluidlevels in both groups. This cross-sectional study recruited Jordanian femalesincluding 40 breast cancer patients … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 20 May 2025 · 4,493 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFactors Associated with Death in Patients COVID-19 at the Epidemic Treatment Center of the Fann National University Hospital, DakarViviane Marie Pierre Cisse, Khardiata Diallo Mbaye, Ndèye Maguette Fall et al.The aim of this study was to identify the factors associated with death in patients monitored for COVID-19 at the Epidemic Treatment Center (ETC) of the Fann National University Hospital (FNUH). This was a cross-sectional, retrospective, descriptive, and analytical study of patients hospitalized for COVID-19 during the period from 1 July 2021 to 31 March 2022. Patients aged 16 years … …American Journal of Infectious Diseases, Vol. 20, Issue 2 · 4 Nov 2024 · 4,263 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCorrelation of Some Tumor Markers Between Serum and Saliva of Patients with Breast CancerHuthaifa Tarawneh, Omar AtroozBreast cancer, which affects 36% of all female oncological patients, is the most frequent cancer in the world among women. Since routine laboratory evaluation of serum can be stressful for patients, it is critical to comprehend the features and limitations of salivary test methods in order to achieve an accurate diagnosis of breast cancer. The purpose of the study is … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 12 Oct 2024 · 4,909 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,494 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNursing Management of Frail Patients with Hematologic Malignancies During COVID-19 Pandemia in the Viterbo Domiciliary Care Unit: Data Analysis from March 2020 to March 2021Silvia Ciambella, Vincenza Innocenti, Elisa Emanueli Cippitelli et al.Background In the Viterbo province, a Domiciliary Hematologic Care Unit (DHCU) for assistance to frail patients (pts) with hemopathies Methods To evaluate the role of nursing management for frail pts followed by DHCU during the first year of the COVID-19 pandemia, all nursing activities from 3/2020 to 3/2021 were analyzed. Results Overall, 107 pts in 43 municipalities of Viterbo province … …International Journal of Research in Nursing, Vol. 15, Issue 1 · 26 Feb 2024 · 8,836 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,825 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClassification of Thoracic X-Ray Images of COVID-19 Patients Using the Convolutional Neutral Network (CNN) MethodRamacos Fardela, Dian Milvita, Mawanda Almuhayar et al.Recently, radiology modalities have been widely used to detect COVID-19. Thoracic X-rays and CT scans are the primary radiological tools utilized in the diagnosis and treatment of individuals with COVID-19. In addition, chest CT scans are more accurate and sensitive in early COVID-19 identification. A new problem arises in diagnosing the results of CT scan images of COVID-19 by radiologists … …Journal of Computer Science, Vol. 20, Issue 4 · 1 Feb 2024 · 5,761 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssociations of HSD17B1 Gene Expression with its DNA Methylation and Estradiol Level in Polycystic Ovary Syndrome Indonesian PatientsRina Puspita, Andon Hestiantoro et al.PCOS's origin and mechanism are still unknown. Epigenetics has been linked to PCOS in an increasing number of studies in recent years. The most extensively researched epigenetic alteration is DNA methylation. During organismal development, DNA methylation can control gene expression by altering transcription factor binding. The alterations in DNA methylation are directly associated with follicular development in PCOS. Studies show … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 8 Jan 2024 · 5,405 accessesView PDFCite