167 articles for “Oxidative Stress”

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Research ArticleOpen accessIn the keywordsEffects of Dietary Emamectin Benzoate at Recommended and Overdose Levels on the Pathophysiological Responses and Tolerability of Oreochromis niloticus at Fry StageJasmine Singha, Thangapalam Jawahar Abraham, Satyen Kumar Panda, Prasanna Kumar PatilEmamectin Benzoate (EB) has been recommended as a feed additive for the control of fish ectoparasites. This investigation examined the impact of dietary EB on physiological responses, antioxidant defence mechanisms, and histopathological changes in key organs, and on the kinetics of residue deposition and elimination in the muscle of Oreochromis niloticus fry. Fry were administered EB feeds at 50 µg … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 1 Jul 2026 · 1,486 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsTaxifolin Potently Diminishes Levels of Reactive Oxygen Species in Living Cells Possibly by Scavenging Peroxyl RadicalsSatoru Sakuma, Yui Kishiwaki, Mayu Matsumura et al.Taxifolin, a naturally occurring dihydroflavonol, has been reported to possess antioxidant activity, whereas there is little information regarding its antioxidant potency as a flavonoid. In the present study, the antioxidant efficacy of taxifolin in living cells was compared to that of catechin, a potent radical scavenger, by using flow cytometry with the redox-sensitive fluorescent dye, 2′,7′-dichlorodihydrofluorescein diacetate. Further, diminishing efficacy … …American Journal of Pharmacology and Toxicology, Vol. 13, Issue 1 · 18 Oct 2018 · 8,058 accessesView PDF Cite

Review ArticleOpen accessIn the keywordsMitochondria are Naturally Micro Robots - A reviewRaffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuThe mitochondrion is a natural robot (cell) with a length of about one micron. Between organisms (plant, animal or human) with its organs and the atomic and molecular components are positioned based cells, which are building all the necessary organs body. Years ago, medical specialists who are studying organ disease have considered that is caused by impaired organ or related … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 18 Nov 2016 · 8,838 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsOne Can Slow Down the Aging through AntioxidantsRaffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuFree radicals are natural nanoparticles which are doing their part well defined in the human cell, but then they must be annihilated or eliminated to not destroy the cell or another part of our body. It has been shown that residual free radicals in the body are responsible for the aging. The role to annihilate them is ful-filled by the … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 8 Dec 2016 · 10,076 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsBiochemical Efficacy of Nigella Sativa Oil and Metformin on Induced Diabetic Male RatsYassmina K. Mahmoud, Sherif Y. Saleh, Abd El Rehim A. El Ghannam, Ibrahim A. IbrahimThis study was carried out to investigate possible beneficial effects of Nigella sativa oil supplementation to diabetic rats. Fifty male Sprague-Dawley rats were randomly divided into five groups (n = 10/group) as follows: group I (normal control), group II (diabetic control), group III (diabetic rats treated with metformin), group IV (diabetic rats treated with metformin and Nigella sativa oil) and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,902 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsPossible Therapeutic Role of Jasonia Candicans and Jasonia Montana Extracts in the Regression of Alzheimer’s Disease in Experimental ModelHanaa H. Ahmed, Hoda F. Booles, Wagdy K.B. Khalil et al.The present article aimed to investigate the potential role of the ethanolic extracts of the aerial parts of Jasonia candicans and Jasonia montana in management of Alzheimer’s Disease (AD) in experimental model. Supplementation of drinking water AlCl3 (0.3%) for 16 weeks induced AD in male rats with siginifcant increase in brain Acetylcholinesterase (AchE) activity, Tumour Necrosis Factor (TNF-α), Transforming Growth … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,832 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsProphylactic Effects of Melatonin on Sodium Valproate-Induced Neural Tube Defects and Skeletal Malformations in Rat EmbryosOmolbanin Rahgazar, Reza Ranjbar, Hossien Najafzadeh Varzi, Mahmood Khaksary MahabadyProblem statement: Some reports showed the teratogenic effects of sodium valproate can be prevented by application of antioxidant drugs and stimulation of the maternal immune system. Therefore, in this study, the prophylactic effect of melatonin on teratogenic effects of sodium valproate was compared. Approach: This study was performed on 31 pregnant rats that were divided into five groups. Control group … …American Journal of Applied Sciences, Vol. 8, Issue 5 · 17 May 2011 · 7,286 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsEndothelial Dysfunction and Insulin Resistance as Pathophysiologic Mechanisms in a Rat Model of PreeclampsiaAyman Z. Elsamanoudy, Amr M. AbbasProblem statement: To assess the plasma concentrations and placental gene expression of soluble fms like tyrosine kinase (sFlt-1), Vascular Endothelial Growth Factor (VEGF), visfatin and Tumour Necrosis Factor α (TNFα) in a rat model of preeclampsia, induced by chronic Reduction of Uterine Perfusion Pressure (RUPP) and to investigate the involvement of Insulin Resistance (IR) in the pathophysiology of preeclampsia and … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,509 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,098 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Selenium Supplementation on Secretion of Reproductive Hormones and Immune Response to Trichostrongylidae Nematodes Infestation in Zulu Sheep Ewes During Oestrous CycleNoxolo Winile Nkunzi, Fhulufhelo V Ramukhithi, Ismaila Muritala et al.The growing resistance of nematodes to anthelmintics has prompted research into alternative control strategies, including nutritional supplementation with micronutrients such as Selenium (Se). Research focusing on the use of mineral supplementation would not only contribute to improvement of animal performance but also to acquaint stakeholders with alternative immune boosting strategies in livestock. Thus, this research assessed how immune response and … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 3 · 27 Oct 2026 · 51 accessesView PDF Cite