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78 articles for “Neurons”
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Research ArticleOpen accessIn the abstractIn Vitro Interaction of 5-Hydroxytrptamine with Cytosolic Molybdenum Hydroxylases as a Potential Inhibitor for Initial Rates ActivitiesAbdullah M. Al-Mohizea, Abd El-Galil E. Amr, Mohamed A. Al-OmarProblem statement: The role of 5-HT has been investigated in many behavioral activities. Thus, studies using raphe lesion showed that 5-HT is involved in sleep, general activity levels, habituation, aggression, pain sensitivity and morphine analgesia, avoidance behavior, self-stimulation and water consumption. Approach: The metabolic interaction between serotonin (5- hydroxytrptamine) and indole-3-aldehyde and xanthine via aldehyde oxidase (EC 1.2.3.1) and xanthine … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractNasal Administration of Quercetin Liposomes Modulate Cognitive Impairment and Inhibit Acetylcholinesterase Activity in HippocampusTerdthai Tong-Un, Supaporn Muchimapura, Wathita Phachonpai, Jintanaporn WattanathornProblem statement: Oxidative stress is a major factor implicated in the degeneration of cholinergic neurons in Alzheimer’s Disease (AD). Several reports have indicated that antioxidant intake is beneficial to delay or inhibit the progression of this disease. Presently, Acetylcholinesterase (AChE) inhibitors are the mainstay of therapy for AD. Quercetin, one of the flavonoids in fruits and vegetables, has a powerful … …Neuroscience International, Vol. 1, Issue 1 · 30 Jun 2010 · 7,170 accessesView PDFCite
Research ArticleOpen accessIn the abstractMyocardial-Infraction Based on Intelligent TechniquesIbrahim Abdulrab AhmedProblem statement: Heart disease is the leading cause of death in the world. One of the most common types of heart diseases is Myocardial-Infraction. The ability to automatically identify Myocardial-Infraction from cardiac profiles test is important for clinical diagnosis and treatment. Approach: The aim of this study is to see whether the heart is healthy or not, in another words … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 7,607 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Constructive Neural Network Architecture for Pattern ClassificationS. S. Sridhar, M. PonnavaikkoProblem statement: Constructive neural network learning algorithms provide optimal ways to determine the architecture of a multi layer perceptron network along with learning algorithms for determining appropriate weights for pattern classification problems. These algorithms initially start with small network and dynamically allow the network to grow by adding and training neurons as needed until a satisfactory solution is found. The … …Journal of Computer Science, Vol. 5, Issue 11 · 30 Nov 2009 · 6,565 accessesView PDFCite
Research ArticleOpen accessIn the abstractDynamic Analysis of Structures Using Neural NetworksN. Ahmadi, R. Kamyab Moghadas, A. LavaeiIn the recent years, neural networks are considered as the best candidate for fast approximation with arbitrary accuracy in the time consuming problems. Dynamic analysis of structures against earthquake has the time consuming process. We employed two kinds of neural networks: Generalized Regression neural network (GR) and Back-Propagation Wavenet neural network (BPW), for approximating of dynamic time history response of … …American Journal of Applied Sciences, Vol. 5, Issue 9 · 30 Sep 2008 · 7,154 accessesView PDFCite
Research ArticleOpen accessIn the abstractCocaine: A Catalyst for Human Immunodeficiency Virus-Associated DementiaNavneet K. Dhillon, Milind Gadgil, Andy Rahardja et al.Injection drug use has been recognized as a major risk factor for AIDS from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States can both impair the functions of macrophages and CD4+ lymphocytes and also activate HIV-1 expression in these cells. Cocaine is a multifactorial agent that acts globally to impair the … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging from Cells to Cognition in Autism Pathophysiology: Biological Pathways to Defective Brain Function and PlasticityMatthew P. Anderson, Brian S. Hooker, Martha R. HerbertWe review evidence to support a model where the disease process underlying autism may begin when an in utero or early postnatal environmental, infectious, seizure, or autoimmune insult triggers an immune response that increases reactive oxygen species (ROS) production in the brain that leads to DNA damage (nuclear and mitochondrial) and metabolic enzyme blockade and that these inflammatory and oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,455 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,184 accessesView PDFCite