76 articles for “Medication”

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Research ArticleOpen accessIn the abstractOsteoporosis Induction in Animal ModelKamran Kaveh, Rashid Ibrahim, Mohd Zuki AbuBakar, Tengku Azmi IbrahimProblem statement: Osteoporosis; the major health problem is an imperative disease requires a significant attention to discover different aspects of this threatening abnormality. There are some problems in osteoporotic human population to conduct researches such as lack of a homogenous sample size or ethical problems. So, there was a need to have protocol in animal model to let the scientists … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 9,305 accessesView PDF Cite

Research ArticleOpen accessIn the abstractApplication of CART Algorithm in Blood Donors ClassificationT. Santhanam, Shyam SundaramProblem statement: This study used data mining modeling techniques to examine the blood donor classification. The availability of blood in blood banks is a critical and important aspect in a healthcare system. Blood banks (in the developing countries context) are typically based on a healthy person voluntarily donating blood and is used for transfusions or made into medications. The ability … …Journal of Computer Science, Vol. 6, Issue 5 · 31 May 2010 · 8,624 accessesView PDF Cite

Research ArticleOpen accessIn the abstractVariability in Antihypertensive Drug Therapy and Compliance: Results from a Random Survey in the United Arab EmiratesSyed Azhar Syed Sulaiman, Muaed Jamal Alomar, Claire Caroline StrauchProblem statement: Hypertension is one of the most common diseases known as the ‘silent killer’ because it shows no clinical signs and symptoms. The high prevalence of hypertension in the United Arab Emirates stresses the importance to initiate a nation-wide effort to prevent and control high blood pressure in the population, especially since the prevalence rates are indicative of one … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,230 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTacrolimus Dosing Challenges in an African American ChildTeresa V. Lewis, Tracy M. Hagemann, Martin A. TurmanIt has been suggested that African Americans have decreased effectiveness with immunosuppressive drugs. Data regarding the pharmacokinetics of tacrolimus in African Americans are limited. We present the case of an African American child in whom management of nephrotic syndrome caused by focal segmental glomerulosclerosis has been challenging due to unpredictable patient specific pharmacokinetic disposition of tacrolimus. Racial differences have been … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2007 · 6,708 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMetabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase InhibitorsMadhu N. Rao, Grace A. Lee, Carl GrunfeldThe use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors for the treatment of HIV infection and AIDS has been associated with multiple abnormalities in glucose and lipid metabolism. Specifically, these abnormalities include insulin resistance, increased triglycerides and increased LDL cholesterol levels. The metabolic disturbances are due to a combination of factors, including the direct effect of medications, restoration to … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,936 accessesView PDF Cite