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99 results for “Genetic Factor”
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EditorialOpen accessIn the abstractVisceral Pain: Basic Research Concepts and Therapeutic InterventionsVictor V. ChabanThe accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 7,148 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulti-Objective Evolutionary Optimization of Sandwich Structures: An Evaluation by Elitist Non-dominated Sorting Evolution StrategyIlyani Akmar, A.B, O. Kramer, T. RabczukIn this study, an application of evolutionary multi-objective optimization algorithms on the optimization of sandwich structures is presented. The solution strategy is known as Elitist Non-Dominated Sorting Evolution Strategy (ENSES) wherein Evolution Strategies (ES) as Evolutionary Algorithm (EA) in the elitist Non-dominated Sorting Genetic algorithm (NSGA-II) procedure. Evolutionary algorithm seems a compatible approach to resolve multi-objective optimization problems because it … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 1 · 22 Apr 2015 · 7,323 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractK121Q Polymorphism of the ENPP1 Gene is Related to Acute Coronary Syndrome in Ukrainian Patients with Normal but not Enhanced Body Mass IndexInna A. Rozumenko, Victoria Y. Garbusova, Yurij A. Ataman et al.Ectonucleotide Pyrophosphatase Phosphodiesterase 1 (ENPP1) is a class II membrane glycoprotein with two unrelated properties: It can hydrolyze extracellular nucleotides and downregulate insulin receptor signaling. The present study was carried out to investigate whether common single-nucleotide polymorphism K121Q (rs1044498) of the ENPP1 gene is associated with Acute Coronary Syndrome (ACS) in the representatives of Ukrainian population and to assess if … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 15 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetecting Patterns in 5’ Untranslated Regions of Genes Involved in the Regulation of Blood Pressure and Oxidative StressMaria Sanchez-Aguilar, Luz Ibarra-Lara, Beatriz Zamora-Lopez et al.Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored. In particular, the 5’ UTR of genes associated with the regulation of blood pressure and oxidative stress are analyzed … …Current Research in Medicine, Vol. 4, Issue 2 · 27 Nov 2013 · 7,283 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutrient and the Mind-Body Axis, in Relation to Omega-3 Fatty Acids and Amino AcidsToru Takahashi, Eri Toda, Ram B. Singh et al.Noncommunicable Diseases (NCDs); obesity, type 2 diabetes mellitus, Cardiovascular Diseases (CVDs) and cancer have become major health problems in both developing and developed countries. Physical inactivity and increased intake of energy rich proinflammatory foods in association with genetic predisposition are common primary risk factors for these problems. Mind-body interactions and mechanisms in relation to hypothalamus neurotransmitters and vagus nerve have … …Current Research in Medicine, Vol. 3, Issue 1 · 17 Feb 2012 · 7,322 accessesView PDFCite
Research ArticleOpen accessIn the abstractSoft Computing in Optimizing Assembly Lines BalancingMuhammad Zaini Matondang, Muhammad Ikhwan JambakAs part of manufacturing systems, the assembly line has become one of the most valuable researches to accomplish the real world problems related to them. Many efforts have been made to seek the best techniques in optimizing assembly lines. Problem statement: Since it was published by Salveson in 1955, some methods and techniques have been developed based on mathematical modeling. … …Journal of Computer Science, Vol. 6, Issue 2 · 28 Feb 2010 · 7,469 accessesView PDFCite
Research ArticleOpen accessIn the abstractFatigue Life Prediction of Screw Blade in Screw Sand Washing Machine under Random Load with Gauss DistributionJie Gong, Yun-Fei Fu, Wen Xia et al.The purpose of this study is to present a new method for estimating the fatigue life of the screw blade in the screw sand washing machine. To ensure the accuracy of numerical simulation, the loading area and the value of load are determined by means of the theoretical analysis. To ascertain the location of the stress peak and stress range, … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 22 Dec 2016 · 8,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractOPTIMAL RESOURCE ALLOCATION FOR LAYERED VIDEO MULTICASTING IN WIMAXHung-Yi Teng, Chun-Hung Wu, Ren-Hung HwangReal-time video disseminations over wireless links such as video telephony, video conferencing and mobile TV have become fast growing applications. In order to cope with the increasing users' demand, a new scalable and efficient wireless distribution platform is needed. With numerous advantages such as QoS assurance, high data rate and wide coverage, WiMAX has been regarded as an ideal choice … …Journal of Computer Science, Vol. 10, Issue 12 · 24 Dec 2014 · 7,410 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,773 accessesView PDFCite