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103 results for “Differentiation”
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Research ArticleOpen accessIn the abstractMicrornas as Double Edged Sword in CancerBaby Joseph, Vrundha M. NairCancer is the leading causes of death world wide. Basically it can be defined as the disease of the cell. One among the mechanism of transfer of a normal cell to cancerous is the alteration in the genetic material DNA. Treatment for cancer remains as a biggest challenge. Here comes the importance of miRNAs. They are endogenous RNA which regulates … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 24 May 2013 · 6,953 accessesView PDFCite
Research ArticleOpen accessIn the abstractVariability and Genetic Structure in a Commercial Field of Tequila Plants, Agave tequilana Weber (Agavaceae)Martha Isabel Torres-Moran, Ana Paulina Velasco-Ramirez, Salvador Antonio Hurtado-de la Pena et al.Crops of the tequila plant (Agave tequilana) are produced mainly from offshoots of mother plants in established commercial fields. This propagation method is significant, as it is believed that it facilitates the spread of disease because of the crop’s low genetic variability and is also necessary because it is regulate the use of just that variety in tequila industry. Different … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 22 Feb 2013 · 8,093 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization of Goats Using Random Amplified Polymorphic DnaNandani Kumari, L. B. Singh, Subodh KumarBlack Bengal goat is a very valuable goat breed in India. The present investigation was proposed to be undertaken to evaluate gene flow, phylogeographic history, genetic structure and differentiation of both the goat populations to study genetic variation prevailing among Black Bengal and Black Bengal type goat in west Bengal and Jharkhand respectively and to study genetic relationship between both … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 20 Feb 2013 · 7,846 accessesView PDFCite
Research ArticleOpen accessIn the abstractSclerostin: A Novel Key to Bone and Dental TreatmentGalli Carlo, Lumetti Simone, Manfredi Edoardo et al.Problem statement: Tooth loss can induce dramatical remodeling of alveolar bone because of mechanical loading impairment and strategies to help maintain adequate bone levels for subsequent therapies are sorely needed. Recent discoveries have shown that osteocytes, matrix-embedded cells in bone, respond to mechanical stimulation by modulating the expression of the Sost gene, which encodes for the protein sclerostin. This protein … …Current Research in Dentistry, Vol. 3, Issue 1 · 1 Jan 2013 · 8,157 accessesView PDFCite
Research ArticleOpen accessIn the abstractRegulation of Retinol Binding Protein 4 Expression and its Relation to Adipogenesis in Bovine AdipocytesMabrouk Ragab EL-Sabagh, Abd Eldaim Mabrouk AttiaAdipogenesis is of great importance in beef cattle. Recent findings indicate that glucose, a substrate for fatty acid biosynthesis and retinoic acid enhance adipogenesis in bovine intramuscular adipocytes. However, other recent findings indicate that Retinol-Binding Protein 4 (RBP4) interferes with glucose uptake and utilization by rodents’ adipocytes. In this study we examined the regulation of RBP4 expression and its relation … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 8,399 accessesView PDFCite
Research ArticleOpen accessIn the abstractRat Model for Poly-AutoimmunityMaria StaykovaAround 30% of the male PVG rats have very low testosterone levels. Upon immunisation with myelin basic protein in complete Freund’s adjuvant they develop experimental autoimmune encephalomyelitis and adjuvant arthritis. The androgen insensitive syndrome in these rats could be used in studies on poly-autoimmunity as well as in studies on variations in the sexual differentiation of brain and behavior. …American Journal of Immunology, Vol. 8, Issue 3 · 7 Sep 2012 · 7,549 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpatial Distribution of Fibroblast Growth Factor Receptor 2 in Normal and Lesioned Central Nervous System of Pleurodeles waltliiMarie Moftah, Marc Landry, Frederic Nagy, Jean-Marie CabelguenFibroblast Growth Factors (FGFs) have been implicated in numerous cellular processes including proliferation, migration, differentiation and neuronal survival. One of these growth factors, Fibroblast Growth Factor 2 (FGF2), is apparently implicated in the ability of the adult salamander (Pleurodeles waltlii) to recover locomotion following complete transection of the spinal cord. In a previous study, we reported up regulation of FGF2 … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 7,145 accessesView PDFCite
Research ArticleOpen accessIn the abstractMonocytes and their Role in Human Immunodeficiency Virus PathogenesisTara Sassé, Jingqin Wu, Li Zhou, Nitin K. SaksenaMonocytes play several significant immunological roles during HIV infection. The phenotypic pliability and the cellular differentiation ability monocytes possess are crucial to the ways they combat infections and control inflammatory processes. The purpose of this review is to provide a comprehensive snapshot of the importance of monocytes in HIV-1 infection and pathogenesis. Moreover, this review also provides newly emerging data … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 8,018 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrornas are Not That Small to IgnoreSanjeev Kumar Srivastava, Sonal Somvanshi, Vivek Pratap SinghMicroRNAs (miRNAs) are small, noncoding RNA molecule that negatively regulates gene expression by causing either degradation or translational inhibition of their target mRNAs. These miRNAs are key regulators of various biological processes such as differentiation, maturation and maintenance of immune homeostasis. Furthermore, deregulated expression of miRNA has now been shown to regulate several disease processes by regulating tumorigenesis, angiogenesis, apoptosis … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,456 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy of Ambient and Indoor Air Quality in the Building Built on the Former LandfillAnuar Ithnin, Nazipah Zakaria, Nor Azura Sulong et al.Problem statement: The air quality study of PPR Taman Wahyu II, Selayang, Selangor was a residential project that was built on the former landfill site. The landfill site will produce landfill gases which can influence the air quality level in and outside the building. Approach: This air quality study also involving PPR Intan Baiduri, Batu Caves, Selangor as a control … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 21 Jun 2012 · 6,989 accessesView PDFCite