Research ArticleOpen accessIn the abstractIMPACT OF DEHYDROEPIANDROSTERONE IN PREVENTION OF PARACETAMOL INDUCED NEPHROTOXICITY IN RATSAbbas O. ElkaribParacetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various human disorders. In this study, the … …Current Research in Medicine, Vol. 5, Issue 1 · 26 Mar 2014 · 7,566 accessesView PDFCite
Research ArticleOpen accessIn the abstractRnai Induced Wing Modification in Leon Mutant Drosophila: A Developmental AnalysisSandeep Satapathy, Cheng Ting ChienThe precision of growth of an animal is meticulously regulated by extrinsic and intrinsic factors, with focus on maintenance of organismal homeostasis. The clue to change in physiology or metabolism of an organism, at times can be derived from the changes in phenotypes. In the Drosophila melanogaster model system, GAL 4-overexpressed RNAi driver males (Mini-White Marker), targeted against specific genes, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 6,717 accessesView PDFCite
Research ArticleOpen accessIn the abstractFlow Cytometry Baseline on Peripheral Leukocyte Cell Profiles for Dairy Goat KidsDarcy M. Fletcher, Megan B. Vogt, Hannah E. Pirner et al.Small ruminants, like goats, would make excellent animal models for not only infectious diseases in large ruminants but also analogous diseases in humans, such as human tuberculosis, Crohn’s disease, melioidosis and brucellosis. The main disadvantage for the small ruminant model is the lack of sufficient baseline data on normal, healthy goat kids. Furthermore, most reagents (antibodies and the like) were … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 26 Sep 2013 · 7,572 accessesView PDFCite
Research ArticleOpen accessIn the abstractIs it Easy to go Green? Consumer Perception and Green ConceptGolnaz Rezai, Phuah Kit Teng, Zainalabidin Mohamed, Mad Nasir ShamsudinA series of health consciousness, environmental and animal welfare issues have brought about awareness among consumers to become conscious of their consumption behaviour. Consumers have begun to search for green products were produced under environmentally friendly conditions and considered green by nature. However, this is only the beginning of the development of the green concept in Malaysia. Thus the objective … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 8,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Leaves Extract Attenuates Male Sexual DysfunctionWipawee Thukhammee, Supaporn Muchimapura, Sitthichai Iamsa-ard et al.Problem statement: At present, the novel agent that is effective, cheap and easy to approach for treating male sexual dysfunction is required due to the current poor therapeutic efficacy. Though Moringa oleifera is reputed for aphrodisiac activity in traditional folklore, no scientific evidence is available. Therefore, we aimed to determine the effect of M.oleifera leaves extract on male sexual behaviors … …Neuroscience International, Vol. 3, Issue 1 · 1 Sep 2012 · 32,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractSilkworm Pupae Protect Against Alzheimer’s DiseaseJintanaporn Wattanathorn, Supaporn Muchimapura, Artit Boosel et al.Silkworm (Bombyx mori) pupae have long been used as food and medicine in Asian countries. It is reputed for the treatment of numerous neurological disorders related to oxidative stress including stroke. Therefore, we hypothesized that silkworm pupae could attenuate memory impairment and neurodegeneration in Alzheimer’s disease. In the present study, we determined the effect of silkworm pupae on the neurodegeneration … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 16 Aug 2012 · 9,697 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Protects Against Age-Related Cognitive DeclineJintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukhammee et al.Problem statement: The phenolic compounds and anthocyanin contents, the antioxidant and Acetylcholinesterase Inhibitor (AChI) activities of mulberry fruits were determined. Approach: Analysis of phenolic compounds and anthocyanin were performed using Folin Ciocalteu reagent and pH-differential method respectively. The antioxidant activity was determined using DPPH and FRAP assays while AChI activity was determined using Ellman method. Results: The mulberry fruit powder … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 8 Aug 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Lam Mitigates Oxidative Damage and Brain Infarct Volume in Focal Cerebral IschemiaWoranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: At present, the therapeutic outcome of cerebral ischemia is still not in the satisfaction level. Therefore, the preventive strategy is considered. Based on the protective effect against oxidative damage of Moringa oleifera Lam. Leaves extract, we hypothesized that this plant extract might protect against cerebral ischemia, one of the challenge problems nowadays. In order to test this hypothesis, … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 3 Aug 2012 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite