77 articles for “Amino Acids”

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Research ArticleOpen accessIn the abstractA Review: Microbiological, Physicochemical and Health Impact of High Level of Biogenic Amines in Fish SauceMuhammad Zukhrufuz Zaman, A. S. Abdulamir, Fatimah Abu Bakar et al.Problem statement: Biogenic amines are basic nitrogenous compounds present in a wide variety of foods and beverages. Their formations were mainly due to the amino acids decarboxylase activity of certain microorganisms. Excessive intake of biogenic amines could induce many undesirable physiological effects determined by their psychoactive and vasoactive action. Fish sauce which is considered as a good source of dietary … …American Journal of Applied Sciences, Vol. 6, Issue 6 · 30 Jun 2009 · 8,920 accessesView PDF Cite

Research ArticleOpen accessIn the abstractHydrophobic, Polar and Hydrogen Bonding Based Drug-Receptor Interaction of TetrahydroimidazobenzodiazepinonesV.K. Sahu, A.K.R. Khan, R.K. Singh, P.P. SinghAnti-HIV drug discovery has been increasingly focusing on HIV-1-RT (reverse transcriptase) as a potential therapeutic target. Tetrahydroimidazobenzodiazepinone (TIBO) belongs to non-nucleoside group of reverse transcriptase inhibitors (NNRTIs). A computational chemistry study has been performed on a series of tetrahydroimidazo-benzodiazepinones as HIV-1-NNRT inhibitors. Problem statement: In order to search out new drug of desired activity from the lead compounds, there was … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 8,839 accessesView PDF Cite

Research ArticleOpen accessIn the abstractC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,564 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPrediction of a Putative Functional Region in the Human Bax Protein by Computational AnalysisMaría Sánchez-Aguilar, Laurence A. Marchat, Absalom ZamoranoStructural domains are relevant elements for interactions between Bcl-2 family members to regulate apoptosis and cell survival. Although BH1-BH4 domains can be identified by their sequence and selective occurrence in Bcl-2-family members, structural regions have not been entirely determined yet. The functional residues of Bax, the most representative pro-apoptotic protein of the human Bcl-2 family, remain almost unknown. Here, we … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,235 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMolecular Characterization of Soybean Mosaic Virus NIa Protein and its Processing Event in Bacterial ExpressionBong K. Choi, Jae S. Park, Hye J. Ahn et al.Soybean mosaic virus (SMV)-CN18 is an Rsv resistance-breaking (RB) isolate to overcome soybean resistance genes Rsv1, Rsv3 and Rsv4. The aim of this study was to characterize nuclear inclusion protein a (NIa protein) of RB isolate at the molecular level and demonstrate its processing into genome-linked protein (VPg) and NIa-Pro domains in Esherichia coli containing a bacterial expression pET vector … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,906 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Meaning of a Redundant Codon: There is Protein Folding Information in Nucleic Acids in Addition to the Genetic CodeJan C. Biro, Josephine M.K. BiroAll the information necessary for protein folding is supposed to be present in the amino acid sequence. It is still not possible to provide specific ab initio structure predictions by bioinformatical methods. It is suspected that additional folding information is present in protein coding nucleic acid sequences, which is not represented by the known genetic code. Nucleic acid subsequences comprising … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 8,297 accessesView PDF Cite

Research ArticleOpen accessIn the abstractExpression, Purification and Activity Assay of Two New Recombinant Antagonists of Fibrinogen ReceptorJianbo Yang, Jia Yao, Kun Yang et al.The gene sequence of Decorsin which is extracted from a kind of North American leeches was synthesized. Two recombinant proteins, Annexin V plus Decorsin (AnnV-D39) and Annexin V plus the carboxyl terminal 27 amino acid residues of Decorsin(AnnV-D27), were constructed. And a 10 amino acids linker peptide of GGGGSGGGGS was inserted between Annexin V and Decorsin in AnnV-D39. Using pET-28(a+) … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,918 accessesView PDF Cite