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Research ArticleOpen accessIn the abstractLeishmania donovani: Immunomodulatory Role of 63KDa Leishmania Antigen in the Promotion of IFN-gamma Response (VL vs HIV-VL Co-infection)Pranati, Sanjiva Bimal, K. Pandey et al.Cytokine behavior of T-lymphocytes is not very clear when a patient is co-infected with Leishmania donovani and HIV. To achieve this we studied groups of patients comprising of VL infected, HIV infected and HIV-VL co-infected cases. As compared to lone infections by either of the infecting agent, the co-infection cases showed greatly diminished CD4 T-cell counts and slightly enhanced values … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioceramics for Tissue Engineering Applications-A ReviewSunho Oh, Namsik Oh, Mark Appleford, Joo L. OngThree dimensional (3-D) scaffolds have been explored in an attempt to persuade the body to heal or repair tissues that do not do so spontaneously. Considerable advances in tissue engineering and regeneration have been accomplished over the last decade. However, the material and 3-D scaffolds ideal for optimal regeneration of missing or lost tissues has not been identified. While current … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 10,423 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmpirical Study on Applications of Data Mining Techniques in HealthcareHarleen Kaur, Siri Krishan WasanThe healthcare environment is generally perceived as being ‘information rich’ yet ‘knowledge poor’. There is a wealth of data available within the healthcare systems. However, there is a lack of effective analysis tools to discover hidden relationships and trends in data. Knowledge discovery and data mining have found numerous applications in business and scientific domain. Valuable knowledge can be discovered … …Journal of Computer Science, Vol. 2, Issue 2 · 28 Feb 2006 · 9,841 accessesView PDFCite
Research ArticleOpen accessIn the abstractSurvival in the Current Healthcare Environment How Close Are We to Socialized Medicine?Eldo E. FrezzaIn the 1980's, some hospitals established internal agencies to regulate cash flow and capital expense. State agencies promoted the evolution of healthcare facilities into more business-like organizations. Attention to the following matters will reduce hospital costs: 1) prevent or reduce nosocomial infections; 2) treat diseases at a stage amenable to outpatient therapy; 3) obtain complete information about the policies of … …Journal of Social Sciences, Vol. 1, Issue 4 · 31 Dec 2005 · 6,693 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory Treatment of Infertility in Men with Elevated Antisperm AntibodiesIvan Bubanovic, Slobodan Kojic, Stevo Najman, Zlatibor AndjelkovicPossible causes of subfertility or infertility in men are still poorly defined, but one important category may be elevated level of antisperm antibodies (ASA) caused by infective and/or autoimmune diseases, as well as injuries of male reproductive system. In this study, blood sera from 45 infertile men of different age with ASA positive ELISA test were examined for the serum … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 8,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractBalancing Treatment and Prevention: The Case of HIV/AIDSJoseph Y.T. MugishaA mathematical model is formulated to study the effect of treatment of HIV/AIDS patients on the spread of the epidemic in a two-age group’s population. The model assumes the sexual transmission mode. A proportion δ, of the adult HIV/AIDS infects is assumed to be receiving treatment. The analysis of the model shows that treatment that is not accompanied by a … …American Journal of Applied Sciences, Vol. 2, Issue 10 · 31 Oct 2005 · 7,035 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cytokines in the Regulation of Glioma Tumour Growth and AngiogenesisChristina Piperi, Athanasios Zisakis, Robert W. Lea, Anastasios KalofoutisMalignant glioblastomas are the most common type of primary brain tumors accounting for more than 50% of all intracranial gliomas. Due to their aggressive nature, recurrent growth, and their extremely poor prognosis for survival, research approaches have made little progress in advancing treatment of these tumours which have the ability of both modulating host immune function and neutralizing immune-based therapies. … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractTowards Identifying Immunogenic Targets in Visceral Leishmaniasis: Role of 17kDa and 63kDa PhosphoproteinsShubhankar K Singh, Sanjiva Bimal, Diwakar S. Dinesh et al.We observed predominant phosphorylation at Protein Kinase C (PKC-α) residue in seven immunoreactive proteins of virulent Leishmania donovani parasites. These phosphoproteins were tested for their ability to stimulate T-cells for secretion of Macrophage Migration Inhibition Factor (MIF) in comparision to crude soluble antigen in Visceral Leishmaniasis (VL) patients. Two of these phosphorylated L. donovani antigens led Leishmania to present these … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,759 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of Probability Curves Obtained from 2 Quantitative Allergen-specific IgE Assays: FEIA and 3gAllergyTMT. M. Li, T. Chuang, S. M. Li, D. Hovanec-BurnsThe validity and benefit of probability curves in allergen-specific IgE (sIgE) testing and their applicability to more than a few allergens are still pending. One study[1] presented probability curves for 4 food allergens and proposed decision points to rule out the need for food challenges in his clinic. Since then, such cutoffs were reported by Boyano-Martinez[2] to be dependent on … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractHistopathological Feature of Acute Appendicitis in Kerman-Iran from 1997 to 2003Fatemeh NabipourAcute appendicitis is one of the most common surgical conditions that affect about seven percent of the population. The histopathologic stages of appendicitis are important to regarding prognosis. To evaluate pathologic features of appendix after operation, this study was designed. 2753 appendices specimen that had been received to department of pathology of two major hospitals in Kerman-Iran during five years … …American Journal of Environmental Sciences, Vol. 1, Issue 2 · 30 Jun 2005 · 6,667 accessesView PDFCite