Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

101 results for “validation analysis”
Set a search alert
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOMBINATION OF CONVENTIONAL AND IN-SILICO APPROACH FOR IDENTIFYING AN INDUSTRIALLY IMPORTANT ISOLATE OF AEROMONASThungri Ghoshal, Sourav Ghosh, Amrita Saha et al.Ammonia is required for various commercial applications while its production by standard process is immensely energy intense. Dairy industry on the other hand produces huge volume of effluent needing treatment before discharge. This study aims at developing an eco-friendly microbial approach for conversion of dairy industry effluent into ammonia under atmospheric pressure and 37°C temperature at laboratory scale. Thus the … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Feb 2014 · 7,921 accessesView PDFCite
Research ArticleOpen accessIn the abstractPartial Least Squares Regression Based Variables Selection for Water Level PredictionsNoraini Ibrahim, Antoni WibowoFloods are common phenomenon in the state of Kuala Krai, specifically in Kelantan-Malaysia. Every year, floods affecting biodiversity on this region and also causing property loss of this residential area. The residents in Kelantan always suffered from floods since the water overflows to the areas adjoining to the rivers, lakes or dams. Months, average monthly rainfall, temperature, relative humidity and … …American Journal of Applied Sciences, Vol. 10, Issue 4 · 7 Apr 2013 · 6,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractTunnel Static Behavior Assessed by a Probabilistic Approach to the Back-AnalysisClaudio Oggeri, Pierpaolo OresteProblem statement: The steps of the validation procedure of the project of a tunnel are briefly illustrated in this study, starting from the geological and structural surveys on the excavation walls and the measurement of the physical and mechanical parameters during the excavation works. Unfortunately, however, the knowledge of the rock mass, which is fundamental to the project, is usually … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 4 Jun 2012 · 7,030 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Discrete Event Simulator for Extensive Defense Mechanism for Denial of Service Attacks AnalysisMaryam Tanha, Seyed Dawood Sajjadi Torshizi, S. ShamalaProblem statement: Seeking for defense mechanisms against low rate Denial of Service (DoS) attacks as a new generation of DoS attacks has received special attention during recent years. As a decisive factor, evaluating the performance of the offered mitigation techniques based on different metrics for determining the viability and ability of these countermeasures requires more research. Approach: The development of … …American Journal of Applied Sciences, Vol. 9, Issue 6 · 21 Mar 2012 · 7,470 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Sequence Based Validation of Gene Expression Microarray DataGerhard G. Thallinger, Eva Obermayr, Pornpimol Charoentong et al.Problem statement: Quantitative Reverse Transcription PCR (RT-qPCR) is often used to validate microarray data. Previous studies show different levels of correlation, without further investigation of influencing factors. Approach: We compared expression levels of 381 genes obtained from microarray hybridizations and from TaqMan based RT-qPCR assays. Correlation of expression levels was determined by comparing: (i) single genes across samples, (ii) all … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 19 Jan 2012 · 13,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractDurian Husk Properties and its Heating Value EquationPatomsok WilaiponProblem statement: Agricultural residue seems to be one of the most promising energy resources for developing countries. Among the other fruits, durian is a popular one for Thai people. Therefore, a large amount of durian husk is left at the shops or factories. This study was aimed to investigate the characteristics and heating value of durian husk and to develop … …American Journal of Applied Sciences, Vol. 8, Issue 9 · 1 Aug 2011 · 7,856 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Resistance to Human Immunodeficiency Virus Protease Inhibitors Using Molecular Mechanics and Machine Learning StrategiesA. Harishchander, D. Alex Anand, Sanjib SenapatiProblem statement: Drug resistance is the most important factor, which influences the failure of current HIV therapies. So, the ability to predict the drug resistance of HIV-1 protease mutants will be useful in developing more effective and longer lasting treatment regimens. Approach: Drug resistance of HIV-1 protease is predicted with two current protease inhibitors (Indinavir and Saquinavir). The problem was … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,204 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment and Early Score Validation of the Malaysian Educator’s Information Technology Attitude Scale (MEITAS)Wong Su LuanThe purpose of this study was to develop and provide initial validation evidence for an instrument to measure educators’ attitudes toward IT. Data were collected from 817 participants comprising both pre and in-service teachers in four phases. Two separate factor analyses were conducted for the pre-service teacher data and in-service teacher data. Principle component analysis, with varimax rotation, suggested three … …American Journal of Applied Sciences, Vol. 4, Issue 8 · 31 Aug 2007 · 7,204 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of an Automatic Blast Furnace through Integrated Simulation ModelingAli Azadeh, S. F. GhaderiThe objective of this study was to develop an integrated simulation model of an automatic blast furnace in a full-scale steelmaking factory. The integrated simulation model introduces a set of optimizing alternatives through sensitivity analysis. The simulation model is built by considering all major and detailed operations and interacting systems of the blast furnace workshop. The workshop is composed two … …Journal of Computer Science, Vol. 2, Issue 4 · 30 Apr 2006 · 7,092 accessesView PDFCite