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64 results for “therapeutic agent”
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Research ArticleOpen accessAll words, across the recordDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,079 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordTherapeutic Potential of Medicinal Plants Grown in the Bundelkhand Region of India for Addressing Severe Non-communicable DiseasesNeelam Kashyap, Abha Sachan, Prakash Chandra et al.Herbal Medicines (HMs) have experienced exponential development in the past few years. Consequently, their natural origins and minimal side effects, the popularity of these medications is gradually growing across the globe. Ancient text Rigveda has well documented the remedial application of medicinal herbs for the management of a spectrum of disorders. Phytometabolites derived from plants are rich in bioactive agents, … …American Journal of Agricultural and Biological Sciences, Vol. 20, Issue 1 · 17 Jun 2025 · 6,958 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordSesame Oil As A Protective Agent Against Doxorubicin Induced Cardio Toxicity In RatKaneez F. Shad, Suhail Al-Salam, Alaaeldin A. HamzaThe therapeutic value of doxorubicin (DXO) as anticancer antibiotic is limited by its cardiotoxicity. This study aimed to investigate the protective effect of sesame oil against DXO-induced cardiotoxicity and oxidative stress. The administration of DXO (20 mg/kg) to Wister male rats, increased serum aspartate aminotransferase and creatine kinase activities (as cardiotoxicity indices) as well as cardiac malondialdehyde and protein carbonyl … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,672 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordNitric Oxide Donors with Therapeutic Strategic in Experimental Schistossomiasis MansoniWander Rogério Pavanelli, Jean Jerley Nogueira da Silva, Carolina Panis et al.Schistosomiasis, an immune disease, remains a major public health problem in endemic area. To determine the influence of Nitric Oxide (NO) on this disease, we tested two compounds (Trans-[Ru(bpy)2(NO)SO3](PF6)-PF6 and Na2[Fe(CN)5(NO)]-SNP, which releases NO when activated by biological reducing agents, in BALB/c mice infected subcutaneously by Schistosoma BH strains. The parasitic activity of NO-donors was evaluated in this model by … …American Journal of Immunology, Vol. 10, Issue 4 · 24 Feb 2015 · 7,852 accessesView PDFCite