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158 articles for “genetic analysis”
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Research ArticleOpen accessIn the abstractGenetic Mutation Assessment of NPM1 Gene and Gene Expression of MDR1 in Iraqi Patients with Acute Myeloid LeukemiaAhmed Abduljabbar Suleiman, Ali Zaid Al-Saffar, Tamadher Abbas Rafaa, Hasan Abdulwahab JwadSince its discovery, mutations in NPM1 have been frequently associated with a large number of Acute Myeloid Leukemia (AML) patients. The vast majority of genetic changes were previously detected in exon 12, however little information report mutations in Nuclear Export Signal region (NES) of NPM1. Sequencing analysis included exon 2 and 3 for 75 Iraqi AML patients showed three SNPs, … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 11 Jan 2018 · 7,784 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimizing Pea Cultivation in Kazakhstan: Breeding Drought-Resistant Varieties for Sustainable AgricultureKudaibergenov Mukhtar Sarsenbekovich, Kanatkyzy Makpal, Saken Gaukhar Sakenkyzy et al.Peas (Pisum sativum L.) are a vital legume for global food security, yet its cultivation in Kazakhstan faces challenges due to arid conditions and limited moisture availability. Breeding high-yielding, stress resistant varieties is critical to enhance agricultural productivity in the region. This study aimed to develop pea varieties with improved yield, drought resistance, and mechanization adaptability under Kazakhstan's agroecological conditions. … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 25 Aug 2025 · 5,254 accessesView PDFCite
Research ArticleOpen accessIn the abstractAgronomic and Fibre Quality Assessment of Cotton Breeding Lines Under Verticillium Wilt ConditionsSabir Makhmadjanov, Amandyk Kostakov, Bakdaulet Asabaev et al.The aim of the study was to identify promising cotton samples with high yield, adaptability, and stable fibre quality. The present work presents the results of a comprehensive assessment of 91 breeding samples of cotton according to economically valuable and technological traits under the conditions of southern Kazakhstan and Uzbekistan in 2024. The comparative analysis identified several promising samples, with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 15 Sep 2026 · 662 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Biochemical and Hormonal Parameters in Male Patients with MigraineDua’a AlHassoon, Omar Atrooz, Husni FarahMigraine is a complex neurological disorder, including hormonal and biochemical imbalances. The physiological changes include neural variations due to genetic, environmental, and lifestyle factors. Therefore, the research aims to investigate total testosterone levels, Acetylcholine (Ach), prolactin, and clinical markers (calcium, magnesium, glucose, and lipid profile) across migraine patients. The research employed a case-control observational design conducted at Al-Ahliyya Amman University, … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 22 Jul 2026 · 823 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimalization of the Swim-Up Method for Bali Bull Sperm: Effect of Incubation Time and Medium on Sperm KineticsAthhar Manabi Diansyah, Muhammad Yusuf, Rahmat et al.Bali bulls (Bos javanicus) are an essential part of Indonesia’s indigenous livestock, prized for their ability to thrive in challenging environments, their natural disease resistance, and their strong reproductive capabilities. The aim of this study was to refine the swim-up technique for preparing Bali cattle sperm. We evaluated the effects of two commonly used media Tyrode's Albumin Lactate Pyruvate (TALP) … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 9 Feb 2026 · 1,696 accessesView PDFCite
InvestigationOpen accessIn the abstractGenetic Structure of Populations of Kazakh Whiteheaded and Hereford Cattles on the Basis of Microsatellite DNAAdas Tileubekovna Tyngoziyeva, Talgat Nikolaevich Karymsakov, Serik Doldashevich NurbaevThis work is aimed at determination of genetic dissimilarities between two allied cattle breeds: Kazakh Whiteheaded and Hereford. Hair follicles were analyzed, from which DNA was extracted with subsequent amplification. Identification of amplification products was performed using an ABI Prism 310 genetic analyzer. Allele 147 was detected in Kazakh Whiteheaded cattle in locus BM 2113, there was no such allele … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 6 Dec 2017 · 7,429 accessesView PDFCite
Research ArticleOpen accessIn the abstractBreeding Progress in Mugalzhar Horses: The Irtysh Type as a Model for Meat Production EfficiencyAkimbekov Amin, Uskenov Rashit, Nurgulsim Kaster et al.The Mugalzhar horse breed holds significant value for meat production in Kazakhstan. Developed through targeted selection, the new Irtysh stud type demonstrates outstanding adaptation and productivity, with stallions reaching an average live weight of 486.1 kg and mares 463.4 kg, an increase of up to 73 kg compared to the original group. The coefficient of variation for live weight and … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 29 Nov 2025 · 2,617 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Adaptive Procedure for the Limit Analysis of FRP Reinforced Masonry Vaults and ApplicationsAndrea Chiozzi, Gabriele Milani, Nicola Grillanda, Antonio TralliThe present paper discusses an adaptive procedure for the kinematic limit analysis of FRP reinforced masonry vaults through applications. The approach relies on a new Genetic Algorithm NURBS-based general framework, which has been recently presented by the authors. The basic idea consists into exploiting the NURBS structure of a CAD geometric 3D model of the selected reinforced masonry vault, in … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 3 · 5 Oct 2016 · 8,529 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico Analysis of three Committed-Steps Involved in Triterpenoid Biosynthesis from Ganoderma lucidumXiaorong Shui, Xiaozhong Lan, Wei LeiGanoderma lucidum is widely considered as one of the most valuable Traditional Chinese Medicines, with various bioactive constituents and pharmaceutical effects. Triterpenoids are important effective ingredients of G. lucidum, which are synthesized mainly through the mevalonate pathway. In this study, we aimed to characterize and analyze three committed-step enzymes of the mevalonate pathway, 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGR), Farnesyl Diphosphate Synthase … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 3 · 15 Aug 2016 · 7,349 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,761 accessesView PDFCite