109 articles for “cell count”

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Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,016 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,960 accessesView PDF Cite

Research ArticleOpen accessIn the abstractClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,111 accessesView PDF Cite

EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnalyze the Absorption Properties and I-V Characterization of Dye Sensitized Solar Cell Using Ruthenium DyeAnees Ur Rehman, Farooq Aslam, Haseeb Ahmad KhanIn this study, Dye Sensitized Solar Cells (DSSC) has been fabricated using natural organic dye extracted from Ruthenium Dye and its I-V characterization and absorption properties have been analyzed. It is observed that the selected natural dye absorbed all visible light and supports electrons motion across the semiconductor interface. The dye acts as sensitizer because the titanium dioxide (TiO2) cannot … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 4 · 30 Dec 2014 · 7,395 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStructural and Evolutionary Analysis of PARPs in D. discoideumA. Mehadvi Kawal, Hina A. Mir, Chethan Kumar Ramniklal et al.Problem statement: Dictyostelium discoideum, a unicellular eukaryote, exhibits multicellularity upon nutrient starvation, making it a better model for developmental studies and for the study of various signal transduction pathways. The most felicitous point of interest is that many of its genes show high degree of similarity to vertebrate genes. Poly (ADP-ribose) polymerase (PARP), a ubiquitous and abundant nuclear protein, has … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,855 accessesView PDF Cite

Research ArticleOpen accessIn the abstractC-Reactive Protein and Serum Procalcitonin Levels as Markers of Bacterial Upper Respiratory Tract InfectionsDiamantis P. Kofteridis, George Samonis, Alexander D. Karatzanis et al.Problem statement: Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain relatively low in viral infections and inflammatory diseases and have … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 7,140 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEmetine produce Entamoeba histolytica Death by Inducing a Programmed Cell DeathJ.D. Villalba-Magdaleno, R. Rojas, C. Gómez et al.Amoebiasis is a major public health problem in tropical and subtropical countries. Although a number of antiamoebic agents are used for its treatment and the molecular targets of these drugs have been identified, the biochemical and physiological mechanisms that produce trophozoite death are little known. The present study dates the in vitro induction of programmed cell death (PCD) in E. … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,214 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGrowth Performance and Blood Profiles of Indigenous Venda Chickens Under Intensive and Semi-Intensive Rearing SystemsBoasiako Oris Antwi, Ifeanyichukwu Princewill Ogbuewu, Christian Anayo MbajiorguA 91-day trial examined the impact of two production systems on crop content, growth performance, hematology, and blood chemistry of indigenous Venda chickens. One-day-old Venda chickens (n = 100) were randomly assigned to two treatments (T1 and T2) and replicated five times with 10 birds per replication. Venda chickens in each group were placed in five replicate pens, each having … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 12 Apr 2026 · 1,428 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGRAPHENE OXIDE AS ANTIMICROBIAL AGAINST TWO GRAM-POSITIVE AND TWO GRAM-NEGATIVE BACTERIA IN ADDITION TO ONE FUNGUSRoda F. Al-Thani, Noorunnisa Khanam Patan, Mariam A. Al-MaadeedGraphene based materials have wide potential applications in biology, biomedical, agriculture environmental and biotechnology. Graphene Oxide (GO) is one of those materials and has a promising substance as antimicrobial agents. GO in this study was prepared by a modified Hummers method and was characterized by different techniques for confirmation of formation of GO. To study the antimicrobial activities of GO, … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 14 Oct 2014 · 9,246 accessesView PDF Cite