Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

98 results for “Wistar rats”
Set a search alert
Research ArticleOpen accessIn the abstractEffect of Dietary Kaempferia parviflora on Ischemic Brain Injury in the ratWathita Phachonpai, Sinthuporn Maharun, Supaporn Muchimapura et al.Problem statement: Stroke often causes irreversible neuronal damage and related behavioral deficits. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional plant medicines. We investigated the ability of consuming Kaempferia parviflora extract, a Thai medicinal plant reputed for neuroprotective effects against brain damage, reduced infarct volume and improve neurological … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 20 Mar 2012 · 9,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Functional Effect of Kaempferia Parviflora on Ischemic Stroke in RatsWathita Phachonpai, Sinthuporn Maharun, Terdthai Tong-Un et al.Problem statement: Oxidative stress has been implicated as important factors in the pathogenesis of cerebral ischemia-induced behavioral deficits particularly memory. Growing attention is being paid to traditional medicinal plants possessing antioxidant activity, as they have been proved therapeutically/prophylactically fruitful against stroke condition. Present study provides evidence of the neroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, against … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 16 Mar 2012 · 8,742 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,247 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Aluminium Chloride on Anxiety-Related BehaviourA.A. Buraimoh, S.A. Ojo, J.O. Hambolu, S.S. AdebisiProblem statement: Aluminium is presents in many manufactured foods, medicines and is also added to drinking water for purification purposes. It has the potential to be neurotoxic in human and animals but its contribution in Alzhemer’s disease remains contradictory. Anxiety affects one-eighth of the total population world-wide and has become an important area of research interest in psychopharmacology. Approach: The … …Neuroscience International, Vol. 2, Issue 2 · 27 Feb 2012 · 7,972 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Cerebral Ischemia of Passiflora foetidaJintanaporn Wattanathorn, Natcha Sattroopinat, Terdthai Tong-Un et al.Problem statement: Although cerebral ischemia induced by stroke has been regarded as the important problem worldwide, the therapeutic efficacy is still inadequate. Since the free radicals are implicated in the pathophysiology of cerebral ischemia, the prophylactic protection against stroke with neuroprotective agent possessing antioxidant effect has gained much attention. Therefore, this study was designed to determine whether the alcoholic extract … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 16 Feb 2012 · 8,245 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruit Mitigates Alcohol Neurotoxicity and Memory Impairment Induced by Chronic Alcohol IntakeJintanaporn Wattanathorn, Nattaporn Phunchago, Supaporn Muchimapura et al.Problem statement: To date, the therapeutic strategy efficacy against memory impairment induced by alcohol intoxication is still limited. The novel therapeutic strategy which is easy to approach, less toxic and less cost is required. Based on the role of oxidative stress in memory impairment induced by alcohol, the neuroprotective effect of substance possessing antioxidant has gained much attention. Therefore, we … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 8 Feb 2012 · 9,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatoprotective Effect of Taurine Against Oxidative Stress Due to Methotrexate in RatE. Issabeagloo, M. Taghizadiyeh, P. KermanizadehProblem statement: Taurine, 2-aminoethanesulphonic acid is an essential amino acid. It is present at high concentrations in many tissues. It plays important roles in numerous physiological functions including conjugation with bile acids, modulation of calcium levels and maintenance of osmolarity, antioxidation and stabilization of membranes. Methotrexate (MTX), as the most disease modifying anti-rheumatic drug used for Rheumatoid Arthritis (RA), has … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 16 Jan 2012 · 8,499 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Test for Two-Sample Repeated Measures Designs: Effect of High-Dimensional DataBoonyarit Choopradit, Samruam ChongcharoenProblem statement: High-dimensional repeated measures data are increasingly encountered in various areas of modern science since classical multivariate statistics, e.g,. Hotelling’s T2, are not well defined in the case of high-dimensional data. Approach: In this study, the test statistics with no specific form of covariance matrix for analyzing high-dimensional two-sample repeated measures designs with common equal covariance are proposed. The … …Journal of Mathematics and Statistics, Vol. 7, Issue 4 · 28 Oct 2011 · 7,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractScreening Neuropharmacological Activities of Kaempferia parviflora (Krachai Dam) in Healthy Adult Male RatsThaneeya Hawiset, Supaporn Muchimapura, Jintanaporn Wattanathorn, Bungorn SripanidkulchaiProblem statement: Although the global prevalence of psychological disorders is increasing continually, the efficacies of therapeutic strategies are still very limited. Oxidative stress has been implicated in the pathogenesis of psychiatric disorders and substance possessing antioxidant activity can alleviate the mentioned conditions. Therefore, we hypothesized that Kaempferia parviflora, a medicinal plant claimed for nerve tonic, also possessed the neuropharmacological activities … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 8,702 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicity evaluation of yoyo 'cleanser' bitters and fields Swedish bitters herbal preparations following sub-chronic administration in ratsMartins Ekor, Odusoga Adewale Osonuga, Adesina Olalekan Odewabi et al.Problem statement: Owing to numerous adverse effects of most orthodox pharmaceuticals, the use of herbal remedies in treatment and prevention of diseases is gaining much attention, especially in developing countries. The increase patronage of these remedies is often predicated on the assumption that they are harmless since they are prepared from natural sources. However, toxicity related to herbal medicines is … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 10,205 accessesView PDFCite