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69 results for “Stimulation”
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Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,578 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Model of Intestinal Anaphylaxis in Whey Sensitized Balb/c MiceNegaoui Hanane, Kaddouri Hanane, Kheroua Omar, Saidi DjamelProblem statement: Cow’s Milk Allergy (CMA) is a common disease in childhood. Pathophysiological mechanisms involved in gastrointestinal symptoms are relatively poorly understood. Approach: Therefore, an experimental model of intestinal anaphylaxis was needed to approach the problem. The aim of this study was to examine the effect of the parenteral sensitization to whey proteins through immune response and local intestine inflammation … …American Journal of Immunology, Vol. 5, Issue 2 · 30 Jun 2009 · 7,126 accessesView PDFCite
Research ArticleOpen accessIn the abstractDengue Virus Infection Induced NF-κB-dependent Macrophage Migration Inhibitory Factor ProductionLien-Cheng Chen, Huey-Wen Shyu, Huan-Yao Lei et al.Dengue virus (DV) infection can cause mild dengue fever or severe dengue hemorrhage fever and dengue shock syndrome. Macrophage migration inhibitory factor (MIF) is a cytokine that plays an important role in the modulation of inflammatory and immune responses and serum levels of MIF are correlated with disease severity in dengue patients. However, the mechanism that induces MIF production during … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,290 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Alloxan-Diabetes on Gastrin-Releasing Peptide (GRP) Immunoreactivity in the Gastrointestinal Tract, of Sprague Dawley Rats and How This May Affect Some of the Diabetic ComplicationsEdward O. Uche-Nwachi, Camille V. MitchellGastrin-releasing peptide (GRP) is the mammalian analogue of bombesin. Both neuroendocrine peptides have similar distribution, functions and immunoreactivity. The immunoreactivity for GRP has been demonstrated in the esophagus, stomach and small intestine. This peptide is reported to have various biological and pharmacological properties, which include the release of gastrointestinal hormones, control of satiety, gastrointestinal motility and stimulation of cellular proliferation … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 31 Dec 2007 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduction of a Soluble Anti-HIV-1 factor (s) with IFN-γ, IL-10, and β-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic MixtureJosé W. Rodríguez, Nat O. Pagan, Mar C. Ocasio et al.Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inactivated influenza and bacterial vaccines called polyantigenic immunomodulator (PAI), possesses strong immunoregulatory and anti- HIV-1 activities. In the present study, we show that culture fluids … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Immunomodulatory Properties of a Calf Lipid Thymus Extract and Standardization of a Method for Quantification of its Biological ActivityMiodrag Colic, Radmila Popovic, Dusanka Mrdakovic et al.The aim of this study was to test the immunobiological properties of a new formulation of the lipid thymus calf extract (Thymsol), prepared for in vitro cell culture experiments. At first, we showed that Thymsol enhanced the antigen specific immune response in AO rats in vitro, using Keyhole limpet hemocyanin (KLH). At lower concentrations (0.5-2.5 μg mL-1) the extract increased … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 7,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign of CHWHG Type Low Frequency Magnetic Fields GeneratorBo Cheng, Ahmed N. Abdalla, Xi Huang et al.Highly considering the invariability of magnetic field strength in the Magnetic Field Generators, which used to stimulate rat's nerve cell, surely improve the stimulation performance outcome. A new technique to get an invariable magnetic field strength within Magnetic Field Generator has been proposed, Furthermore it had implemented on microcontroller-based system providing an Alternating Magnetic Field Generator (AMFG) with a high … …Journal of Computer Science, Vol. 3, Issue 2 · 28 Feb 2007 · 6,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Deep Ensemble Framework for DDoS Attack Recognition and Mitigation in Cloud SDN EnvironmentS. Annie Christila, R. SivakumarMuch research has been done in the recent past on the absolute shift of Internet infrastructure in order to make it more significantly programmable, configurable and make it more conveniently feasible. Software Defined Networking (SDN) forms the basis for this absolute shift in Internet infrastructure. When you look at the benefits of an SDN-based cloud environment they are monumental. Namely, … …Journal of Computer Science, Vol. 20, Issue 10 · 5 Aug 2024 · 5,337 accessesView PDFCite