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182 articles for “Diabetes”
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Research ArticleOpen accessIn the keywordsEffect of Streptozotocin-Induced Hyperglycemia on the Progression of Hepatocarcinogenesis in RatsChowdhury Mobaswar Hossain, Bhabani Sankar Satapathy, Laboni Mondal et al.Diabetes mellitus and hepatocellular carcinoma both have detrimental impact on health worldwide. Type II diabetes and liver cancer share many causative factors, but biological correlation between the two diseases still remains elusive. The study was aimed to evaluate the effect of induction of diabetes during the development of hepatocarcinogenesis in rats. Rats were divided into four groups namely, normal control, … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 4 Nov 2013 · 7,521 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCinnamon Extract Regulates Gene Expression of Lipid and Carbohydrate Metabolism in Streptozotocin Induced Diabetic Wistar RatsMohamed Mohamed Soliman, Mohamed Mohamed Ahmed, Samir Ahmed El-ShazlyCinnamon is a herbal medication plant used widely for many diseases in the Middle East and ancient countries. Cinnamon Extract (CE) contains many active substances that modulate insulin sensitivity and acts as anti-diabetic medication. Diabetes mellitus is a disease characterized by disturbance in carbohydrate and lipid metabolism. The aim of this study was to examine the effect of Cinnamon Extract … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,048 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of a Self-Management Support Program on Diabetic Foot Care BehaviorsWipa Sae-Sia, Khomapak Maneewat, Titis KurniawanDiabetic Foot Care Behaviors (DFCB) is the fundamental component of diabetic foot complications prevention. Many diabetic patients, however, did not perform foot care properly. Furthermore, Self-Management (SM) support program was noted as effective approach improving diabetes patients’ behaviors. Unfortunately, there have been no studies published applied this approach to improve DFCB in Indonesia. This study aimed to determine the effectiveness … …International Journal of Research in Nursing, Vol. 4, Issue 1 · 4 May 2013 · 12,946 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMicrornas are Not That Small to IgnoreSanjeev Kumar Srivastava, Sonal Somvanshi, Vivek Pratap SinghMicroRNAs (miRNAs) are small, noncoding RNA molecule that negatively regulates gene expression by causing either degradation or translational inhibition of their target mRNAs. These miRNAs are key regulators of various biological processes such as differentiation, maturation and maintenance of immune homeostasis. Furthermore, deregulated expression of miRNA has now been shown to regulate several disease processes by regulating tumorigenesis, angiogenesis, apoptosis … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,460 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSex, Health Behaviors and Social Support: Functional Decline among Older DiabeticsEmily Joy NicklettProblem statement: Men and women experience pronounced differences in functional decline as they age. The mechanisms behind these differences remain unclear, particularly among chronically ill populations. Drawing on the theory of the disablement process, this research examines sex differences in functional decline, focusing on two mechanisms suggested by the literature to partially mediate these disparities: health behaviors and social support. … …Current Research in Medicine, Vol. 3, Issue 2 · 19 May 2012 · 8,048 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Cardio-Metabolic Risk Factors among Young Adult FemalesSwati Dhruv, Uma Iyer, Kusum BhattProblem statement: Over the past two decades there has been a striking increase in the number of people with metabolic syndrome in developing countries. The current study was thus undertaken to map the prevalence of Metabolic Syndrome (MS) and to assess the cardio-metabolic risk factors among young adult females (n = 1303) aged 18-26y from four girls hostel of the … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 7,877 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBayesian Determination of Disease Associated Differences in Haplotype BlocksIvan Kozyryev, Jing ZhangProblem statement: While experimental ascertainment of haplotype blocks in the genome-scale case-control studies is expensive, accurate computational phasing is still a daunting task for bioinformatics approaches. We used a statistical method to determine differences, potentially associated with a certain disease, in linkage disequilibrium block boundaries in whole-genome Single Nucleotide Polymorphisms (SNPs) data. Approach: We utilized a Bayesian model for calculating … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 14 Feb 2012 · 8,428 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of Camel's Milk as a Vehicle for Insulin on Glycaemic Control and Lipid Profile in Type 1 DiabeticsMohamed-I Kotb-El-Sayed, Zakaria-Y Al-Shoeibi, Ahmed-A Abd El-Ghany, Zayed-A AtefProblem statement: To evaluate effects of oral insulin carried by camel’s milk on type 1 diabetes patient in comparison with both insulin injection requirements and camel’s milk alone. Approach: Total of fifty randomly selected type 1 diabetic subjects were divided into three groups; A, B and C (n = 15). All subjects received a usual care (diet, exercise and insulin … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 11 Feb 2012 · 8,472 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBiomarkers of Oxidative DNA Damage and Soluble Fas/Fas Ligand in Type 2 Diabetic PatientsMohamed H. Mahfouz, Ibrahim A. Emara, Ghada A. OmarProblem statement: Involvement of oxidative stress in the pathogenesis of diabetic complications has been proposed. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been reported to serve as a new sensitive biomarker of the oxidative DNA damage in vivo. Apoptosis via Fas/Fas Ligand (FasL) interactions has been proposed to be a major T-cell-mediated effector mechanism in autoimmune diabetes. This study was undertaken to investigate whether … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 3 Feb 2012 · 7,110 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Bayesian Method for Disentangling Dependent Structure of Epistatic InteractionJing Zhang, Qu Zhang, Darrin Lewis, Michael Q. ZhangProblem statement: We propose a Bayesian method (RBP) to recursively infer the independence structure of epistatic interactions in case-control study. Approach: Based on the results of BEAM2, RBP can powerfully detect the marginal and conditional independence within interacting SNPs even in the complicated interaction cases. Results: We did extensive simulations to test RBP and compare it with stepwise logistic regression. … …Current Research in Biostatistics, Vol. 2, Issue 1 · 13 Jan 2012 · 7,481 accessesView PDFCite